Evaluation of parasite and host phenolic composition and bioactivities − The Practical Case of Cytinus hypocistis (L.) L. and Halimium lasianthum (Lam.) Greuter
2022
Аутори:
Silva, Ana RitaAyuso, Manuel
Pereira, Carla
Dias, Maria Inês
Kostić, Marina
Calhelha, Ricardo C.
Soković, Marina
García, Pablo A.
Ferreira, Isabel C.F.R.
Barros, Lillian
Тип документа:
Чланак у часопису (Објављена верзија)
,
© 2021 Elsevier B.V.
Метаподаци
Приказ свих података о документуАпстракт:
Cytinus hypocistis (L.) L. is a comestible holoparasite with great potential for cosmeceutical application. Although its high tannin content has been associated with its bioactive and inhibitory enzyme properties, this is the first report establishing a relationship between parasite and host (Halimium lasianthum (Lam.) Greuter) phenolic profile and bioactive properties. Thus, five extracts (aerial and root extracts of non-parasited and parasited H. lasianthum and C. hypocistis) were evaluated. The tentative identification of both species comprises 39 phenolic compounds. Hydrolysable tannins and flavonoids were the main identified groups in C. hypocistis and H. lasianthum extracts, respectively. Regarding bioactivities, C. hypocistis exhibited excellent antioxidant results both in Oxidative Haemolysis (OxHLIA) and inhibition of Thiobarbituric Acid Reactive Substances Formation (TBARS). The tested extracts presented antimicrobial inhibition, anti-inflammatory activity, and effective cytotoxicity against tumour cells. C. hypocistis exhibited the lowest cytotoxicity on a non-tumour cell line. Principal Component Analysis (PCA) was a suitable approach to analyse differences among samples, explaining up to 67% of data variability and suggesting no similarities between parasite and host phenolic composition and bioactivities. Therefore, this comparative study emphasises the significance of both species as a source of biologically active compounds.
Кључне речи:
Antimicrobial; Antioxidant; Cytotoxicity; Flavonoids; Tannins; Tyrosinase inhibitionИзвор:
Industrial Crops and Products, 2022, 176, 114343-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200007 (Универзитет у Београду, Институт за биолошка истраживања 'Синиша Станковић') (RS-MESTD-inst-2020-200007)
DOI: 10.1016/j.indcrop.2021.114343
ISSN: 0926-6690
WoS: 000736972500007
Scopus: 2-s2.0-85120947076
URI
https://linkinghub.elsevier.com/retrieve/pii/S0926669021011080http://radar.ibiss.bg.ac.rs/handle/123456789/4746