Comparative study on the phenolic composition and in vitro bioactivity of medicinal and aromatic plants from the Lamiaceae family
2022
Аутори:
Mascoloti Spréa, RafaelCaleja, Cristina
Pinela, José
Tiane C., Finimundya
Calhelha, Ricardo C.
Kostić, Marina
Soković, Marina
Prieto, Miguel A.
Pereira, Eliana
Amarala, Joana S.
Barros, Lillian
Тип документа:
Чланак у часопису (Објављена верзија)
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© 2022 Elsevier Ltd.
Метаподаци
Приказ свих података о документуАпстракт:
Medicinal and aromatic plants (MAP) have been described as a source of phenolic compounds with potential as antioxidant, antiproliferative and antimicrobial agents. MAP from the Lamiaceae family (Origanum vulgare L., Thymus vulgaris L., Ocimum basilicum L., Salvia officinalis L., Melissa officinalis L., and Matricaria chamomilla L.) were selected to perform a phytochemical and biological screening for their further exploitation as natural bioactive ingredients. The total content of phenolic compounds varied from 184.02 mg/g extract in M. officinalis to 17.97 mg/g extract in M. chamomilla. Caffeic and rosmarinic acids were the main phenolic acids found in the respective hydroalcoholic extracts. The extracts showed a promising antioxidant activity in vitro, being related the phenolic compositions of the extracts, furthermore, all extracts being able to combat lipid peroxidation in TBARS assays with an IC50 under 26 μg/mL, moreover all the plant extract has prevented the oxidative haemolysis in OxHLIA assays at concentrations below 67 μg/mL in a Δt 60 min and under 118 μg/mL for a Δt 120 min. Regarding to the bactericidal and fungicidal action the plant extracts were able to inhibit growth against bacteria associated with food hazards, such as Salmonella typhimurium (MIC < 1) and Listeria monocytogenes (MIC < 1), regarding to fungicidal activity it can be highlighted the MIC values under to 0.25 for Aspergillus versicolor and Trichoderma viride. Overall, the selected Lamiaceae plants stood out as a source of active phytochemicals that can be used by different industries, such as food and cosmetics.
Кључне речи:
Biological bioactivity; Phytochemical composition; Lamiaceae family; Medicinal and aromatic plants; Phenolic compoundsИзвор:
Food Research International, 2022, 161, 111875-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200007 (Универзитет у Београду, Институт за биолошка истраживања 'Синиша Станковић') (RS-MESTD-inst-2020-200007)
- Foundation for Science and Technology (FCT, Portugal)
- BEONNAT (BBI-2019-SO1-R1 -887917)
- Healthy-PETFOOD (POCI-01-0247-FEDER-047073)
- "BIOMA - Bioeconomy integrated solutions for the mobilization of the Agro-food market" (POCI-01-0247-FEDER-046112)
DOI: 10.1016/j.foodres.2022.111875
PubMed: 36192910