Prenylated Flavonoids of the Moraceae Family: A Comprehensive Review of Their Biological Activities
Аутори:
Morante-Carriel, JaimeŽivković, Suzana
Nájera, Hugo
Sellés-Marchart, Susana
Martínez-Márquez, Ascensión
Martínez-Esteso, María José
Obrebska, Anna
Samper-Herrero, Antonio
Bru-Martínez, Roque
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
Prenylated flavonoids (PFs) are natural flavonoids with a prenylated side chain attached to the flavonoid skeleton. They have great potential for biological activities such as anti-diabetic, anti-cancer, antimicrobial, antioxidant, anti-inflammatory, enzyme inhibition, and anti-Alzheimer’s effects. Medicinal chemists have recently paid increasing attention to PFs, which have become vital for developing new therapeutic agents. PFs have quickly developed through isolation and semi- or full synthesis, proving their high value in medicinal chemistry research. This review comprehensively summarizes the research progress of PFs, including natural PFs from the Moraceae family and their pharmacological activities. This information provides a basis for the selective design and optimization of multifunctional PF derivatives to treat multifactorial diseases.
Кључне речи:
flavonoids; prenylated compounds; Moraceae family; bioactivitiesИзвор:
Plants, 2024, 13, 9, 1211-Финансирање / пројекти:
- Spanish Ministry of Science and Innovation, MCIN/AEI/10.13039/501100011033
- Valencian Conselleria d’Innovació, Universitats, Ciencia y Societat Digital grant CIAICO/2021/167
- RDF A way of making Europe, and European Union NextGenerationEU/PRTR grants PID2020-113438RB-I00 and TED2021-129617B-I00
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200007 (Универзитет у Београду, Институт за биолошка истраживања 'Синиша Станковић') (RS-MESTD-inst-2020-200007)