Bioactive formulations prepared from fruiting bodies and submerged culture mycelia of the Brazilian edible mushroom Pleurotus ostreatoroseus Singer
2015
Authors:
Gomes Correa, Rubia CarvalhoHenrique Pereira de Souza, Aloisio
Calhelha, Ricardo C.
Barros, Lillian
Glamočlija, Jasmina
Soković, Marina
Peralta, Rosane Marina
Bracht, Adelar
Ferreira, Isabel C. F. R.
Document Type:
Article (Published version)
,
© The Royal Society of Chemistry 2015
Metadata
Show full item recordAbstract:
Pleurotus ostreatoroseus is a Brazilian edible mushroom whose chemical
characterization and bioactivity still remain underexplored. In this
study, the hydrophilic and lipophilic compounds as well as the
antioxidant, anti-inflammatory and antimicrobial activities of
formulations (ethanol extracts) prepared with its fruiting bodies and
submerged culture mycelia were compared. The bioactive formulations
contain at least five free sugars, four organic acids, four phenolic
compounds and two tocopherols. The fruiting body-based formulation
revealed higher reducing power, DPPH scavenging activity, beta-carotene
bleaching inhibition and lipid peroxidation inhibition in brain
homogenates than the mycelium-based preparation, as well as higher
anti-inflammatory and antimicrobial activities. The absence of
hepatotoxicity was confirmed in porcine liver primary cells. These
functional responses can be related to the levels of bioactive
components including phenolic acids, organic acids and tocopherols.
Source:
Food & Function, 2015, 6, 7, 2155-2164Funding / projects:
- Characterization and application of fungal metabolites and assessment of new biofungicides potential (RS-MESTD-Basic Research (BR or ON)-173032)
- Pest-OE/AGR/UI0690/2014
- SFRH/BPD/68344/2010
- CAPES fellow, process number BEX3974/14-6
DOI: 10.1039/c5fo00465a
ISSN: 2042-650X