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Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs
dc.creator | Omar, Kouatli | |
dc.creator | Geronikaki, Athina | |
dc.creator | Zoumpoulakis, Panagiotis | |
dc.creator | Camoutsis, Charalabos | |
dc.creator | Soković, Marina | |
dc.creator | Ćirić, Ana | |
dc.creator | Glamočlija, Jasmina | |
dc.date.accessioned | 2020-01-31T09:36:20Z | |
dc.date.available | 2020-01-31T09:36:20Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 0968-0896 | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/3588 | |
dc.description.abstract | As part of ongoing studies in developing new antimicrobials, a class of structurally novel 4-thiazolidinone derivatives incorporating three known bioactive nuclei such as thiazole, thiazolidinone and adamantane was synthesized by the multi-step reaction protocol, already reported in the literature. NMR and Molecular Modeling techniques were employed for structure elucidation and Z/E potential isomerism configuration of the analogues. Evaluation of antibacterial and antifungal activity showed that almost all compounds exhibited better results than reference drugs thus they could be promising candidates for novel drugs. | en |
dc.publisher | Elsevier BV | en |
dc.rights | restrictedAccess | |
dc.source | Bioorganic & Medicinal Chemistry | en |
dc.subject | 4-Thiazolidinone | |
dc.subject | Antibacterial | |
dc.subject | Antifungal | |
dc.subject | Z/E isomerism | |
dc.title | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs | en |
dc.type | article | en |
dc.rights.license | ARR | |
dcterms.abstract | Цамоутсис, Цхаралабос; Ћирић, Aна; Соковић, Марина; Героникаки, Aтхина; Гламочлија, Јасмина; Омар, Коуатли; Зоумпоулакис, Панагиотис; | |
dc.rights.holder | © 2009 Elsevier Ltd. | |
dc.citation.issue | 1 | |
dc.citation.volume | 18 | |
dc.identifier.doi | 10.1016/j.bmc.2009.10.041 | |
dc.identifier.pmid | 19914077 | |
dc.identifier.scopus | 2-s2.0-72149105339 | |
dc.identifier.wos | 000272892100046 | |
dc.citation.spage | 426 | |
dc.citation.epage | 432 | |
dc.type.version | publishedVersion | |
dc.citation.rank | M21 |
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