dc.creator | Selaković, Vesna | |
dc.creator | Rauš Balind, Snežana | |
dc.creator | Radenović, Lidija | |
dc.creator | Prolić, Zlatko | |
dc.creator | Petković, Branka | |
dc.date.accessioned | 2020-07-20T09:01:30Z | |
dc.date.available | 2900-01-01 | |
dc.date.issued | 2013 | |
dc.identifier.issn | 1085-9195 | |
dc.identifier.uri | https://link.springer.com/article/10.1007/s12013-012-9498-z | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/3785 | |
dc.description.abstract | The aim of study was to investigate the effects of extremely low frequency magnetic field (ELF-MF; 50 Hz; 0.1, 0.25 and 0.5 mT) on oxidative stress in the brain of 3- (adult) and 10-month-old (middle-aged) gerbils. Nitric oxide (NO) level, superoxide (O2-) production, superoxide dismutase (SOD) activity, and index of lipid peroxidation (ILP) were measured in the forebrain cortex, striatum, hippocampus, and cerebellum immediately and 3 days after cessation of 7-day exposure. In all gerbils, ELF-MF significantly increased oxidative stress in all tested brain regions. This effect was correlated with the value of magnetic induction and was higher in middle-aged gerbils. Three days after cessation of exposure, the values of examined parameters were closer to control levels. In adult gerbils, the effect of ELF-MF of 0.1 mT on NO level, O2- production and SOD activity was almost fully disappeared, and ILP was at the control level regardless of the value of magnetic induction. In middle-aged gerbils, the effect of ELF-MF was still present but to a lesser degree than those observed immediately after cessation of exposure. These findings pointed out the ability of ELF-MF to induce age- and magnetic induction-dependent modification of oxidative stress in the brain. | en |
dc.language.iso | en | sr |
dc.publisher | Humana Press Inc. | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173027/RS// | sr |
dc.relation | MMA Grant (VMA/06-10/B.4) | sr |
dc.rights | restrictedAccess | sr |
dc.source | Cell Biochemistry and Biophysics | sr |
dc.subject | 50 Hz magnetic field | sr |
dc.subject | Oxidative stress | sr |
dc.subject | Brain | sr |
dc.subject | Aging | sr |
dc.subject | Gerbils | sr |
dc.title | Age-Dependent Effects of ELF-MF on Oxidative Stress in the Brain of Mongolian Gerbils | en |
dc.type | article | sr |
dc.rights.license | ARR | sr |
dcterms.abstract | Селаковић, Весна; Петковић, Бранка; Пролић, Златко; Раденовић, Лидија; Рауш Балинд, Снежана; | |
dc.rights.holder | © Springer Science+Business Media New York 2013 | sr |
dc.citation.issue | 3 | |
dc.citation.volume | 66 | |
dc.identifier.doi | 10.1007/s12013-012-9498-z | |
dc.identifier.pmid | 23292355 | |
dc.identifier.scopus | 2-s2.0-84880934332 | |
dc.identifier.wos | 000322526500009 | |
dc.citation.spage | 513 | |
dc.citation.epage | 521 | |
dc.type.version | publishedVersion | sr |
dc.citation.rank | M21 | |