Temporal patterns of extremely low frequency magnetic field-induced motor behavior changes in Mongolian gerbils of different age
2012
Authors:
Petković, BrankaSelaković, Vesna
Rauš Balind, Snežana
Radenović, Lidija
Zrnić, Mila
Prolić, Zlatko
Document Type:
Article (Published version)
,
© 2012 Informa UK, Ltd.
Metadata
Show full item recordAbstract:
Purpose: The aim of this study was to investigate the influence of extremely low frequency magnetic field (ELF-MF) on different behavior parameters (locomotion, stereotypy, and immobility) in 3- and 10-month-old male Mongolian gerbils. Materials and methods: The animals were continuously exposed to ELF-MF (50 Hz; 0.1, 0.25 and 0.5 mT) for seven days. Their behavior was monitored for 60 min in the open field after the 1st, 2nd, 4th, and 7th day of exposure (immediate effect), and three days after ELF-MF exposure had been ceased (delayed effect). Results : In 3-month-old gerbils, exposure to ELF-MF (0.1, 0.25 and 0.5 mT) increased motor behavior (locomotion and stereotypy), and consequently decreased immobility. Additionally, ELF-MF had delayed effect (except 0.25 mT) on stereotypy and immobility. In 10-month-old gerbils, ELF-MF of 0.1, 0.25 and 0.5 mT induced decrease, slight increase, and pronounced stimulation of motor behavior, respectively. Regardless of magnetic induction value, increased motor behavior was observed three days after ELF-MF exposure has been ceased (delayed effect). Conclusions: It can be proposed that the specific temporal patterns of ELF-MF-induced motor behavior changes in 3- and 10-month-old gerbils are a consequence of age-dependent morpho-functional differences in the brain structures responsible for a control of motor behavior.
Keywords:
Magnetic field; 50 Hz; Locomotion; Stereotypy; Immobility; Aging; GerbilsSource:
International Journal of Radiation Biology, 2012, 88, 4, 359-366Funding / projects:
- The effects of magnetic fields and other environmental stressors on the physiological responses and behavior of different species (RS-MESTD-Basic Research (BR or ON)-173027)
- MMA Grant (VMA/06-10/B.4)
DOI: 10.3109/09553002.2012.652725
ISSN: 0955-3002
PubMed: 22221164
WoS: 000302163000008
Scopus: 2-s2.0-84859347938
URI
https://www.tandfonline.com/doi/full/10.3109/09553002.2012.652725https://radar.ibiss.bg.ac.rs/handle/123456789/3802