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Organ-specificity and genotype-dependency of secoiridoid glucosides’ constitutive biosynthesis in Centaurium erythraea Rafn
dc.contributor | Uzelac, Branka | |
dc.creator | Nikolić, Tijana | |
dc.creator | Matekalo, Dragana | |
dc.creator | Skorić, Marijana | |
dc.creator | Novaković, Lazar | |
dc.creator | Božunović, Jelena | |
dc.creator | Aničić, Neda | |
dc.creator | Mišić, Danijela | |
dc.date.accessioned | 2021-09-01T13:05:21Z | |
dc.date.available | 2021-09-01T13:05:21Z | |
dc.date.issued | 2018 | |
dc.identifier.isbn | 978-86-912591-4-3 | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/4291 | |
dc.description.abstract | Plant species Centaurium erythraea Rafn (fam. Gentianaceae) is characterized by the presence of secoiridoid glucosides (SGs) as dominant secondary metabolites. The SG biosynthetic pathway has not yet been fully elucidated, despite the great pharmacological importance of this species. Here, an insight into the SG biosynthesis is achieved by comparing chemical profiles and secoiridoid- related gene expression patterns of different C. erythraea genotypes and plant organs. The results revealed that leaves are the main site of secoiridoid biosynthesis and accumulation in C. erythraea. The key function in the secoiridoid glucoside biosynthetic pathway has been assigned to genes encoding GES, G8O, 8HGO, 7DLGT and 7DLH2, while for SLS and CPR a potential biosynthetic- flux regulatory role has been determined. The correlation between the levels of these genes’ expression and SG content is evident in different plant organs. Also, the analysis of SG high- and low-productive genotypes of C. erythraea points out that chemical variability existing at intra-species level is, at least partially, determined by the different patterns of expression of SG-related genes in different genotypes. Taking into consideration the biological activity of secoiridoid glucosides, not only is the information obtained in this study of importance for further SG biosynthesis elucidation, but it also shows a great potential for future biotechnology-based sustainable production of these valuable metabolites. | sr |
dc.language.iso | en | sr |
dc.publisher | Belgrade: Serbian Plant Physiology Society | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173024/RS// | sr |
dc.rights | openAccess | sr |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | Joint Meeting of 3rd International Conference on Plant Biology, 22nd Symposium of the Serbian Plant Physiology Society. Belgrade, Serbia. Book of abstracts | sr |
dc.subject | Centaurium erythraea Rafn | sr |
dc.subject | secoiridoid glycosides | sr |
dc.subject | qPCR | sr |
dc.subject | UHPLC-MS/MS | sr |
dc.title | Organ-specificity and genotype-dependency of secoiridoid glucosides’ constitutive biosynthesis in Centaurium erythraea Rafn | sr |
dc.type | conferenceObject | sr |
dc.rights.license | ARR | sr |
dcterms.abstract | Матекало, Драгана; Скорић, Маријана; Новаковић, Лазар; Божуновић, Јелена; Aничић, Неда; Мишић, Данијела; Николић, Тијана; | |
dc.rights.holder | © 2018 by the Serbian Plant Physiology Society | sr |
dc.description.other | Uzelac B, editor. Book of abstracts. 3rd International Conference on Plant Biology (22nd SPPS Meeting); 2018 Jun 9-12; Belgrade, Serbia. Belgrade: Serbian Plant Physiology Society; Institute for Biological Research "Siniša Stanković"; Faculty of Biology; 2018. p. 126. | sr |
dc.citation.spage | 126 | |
dc.type.version | publishedVersion | sr |
dc.identifier.cobiss | 264415756 | |
dc.identifier.fulltext | https://radar.ibiss.bg.ac.rs/bitstream/id/8743/3-IntConfPlantBiology_2018-126.pdf | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_ibiss_4291 |