Phytochemical characterisation, in vitro antioxidant and antidiabetic activity of Rosa arvensis Huds. extracts
2022
Authors:
Žarković, Lazar D.Mileski, Ksenija S.
Matejić, Jelena S.
Gašić, Uroš
Rajčević, Nemanja F.
Marin, Petar
Džamić, Ana M.
Document Type:
Article (Published version)
,
© 2022 Elsevier Ltd.
Metadata
Show full item recordAbstract:
In this study, the chemical composition, antioxidant, and hypoglycemic activity of Rosa arvensis Huds. leaves and fruits collected from Zlatibor, Željin, Veliki Krš mountains and Petnica village (Serbia) were analysed. Phenolic and vitamin profiles, as well as in vitro antioxidant potential and enzyme inhibitory activity on α-amylase and α-glucosidase, were studied. Phytochemical analysis showed higher phenolic content in leaf extracts than in those obtained from fruits. Gallic, chlorogenic and syringic acids were the most abundant phenolic acids, while catechin was the major flavonoid compound. Furthermore, the highest level of α-tocopherol (1.94 mg/100 g fw) in achenes and ascorbic acid (9.60 mg/100 g fw) in hypanthium were quantified in the fruits sampled on the Veliki Krš Mt. High antioxidant capacity was observed for the leaf extracts. It was highly correlated with their chemical composition and primarily referred to the catechin content (r > 0.95, p < 0.01), while the quinic acid had the opposite effect (r > −0.97, p < 0.01). Leaf extracts also showed good α-glucosidase and moderate α-amylase inhibitory potential in contrast to hypanthium and achenes extracts with lower antidiabetic activity. The high phenolic content and noted antioxidative potential were strongly correlated with the α-glucosidase inhibitory activity (r > 0.80, p < 0.01), while the α-amylase inhibition was only moderately correlated with those compounds (r > 0.49, p < 0.01). Among the tested R. arvensis samples, those from Zlatibor Mt. contained the highest amount of target compounds and expressed the highest biological activity. The obtained results suggest that R. arvensis extracts present a new source of bioactive compounds that could be implemented as novel food ingredients.
Keywords:
Antioxidant activity; Enzyme inhibition; HPLC; Phenolics; Vitamins; Wild rosesSource:
Food Bioscience, 2022, 50, 102125-Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200178 (University of Belgrade, Faculty of Biology) (RS-MESTD-inst-2020-200178)
DOI: 10.1016/j.fbio.2022.102125
ISSN: 2212-4292
WoS: 000896011500008
Scopus: 2-s2.0-85143500662
URI
https://linkinghub.elsevier.com/retrieve/pii/S2212429222005855http://radar.ibiss.bg.ac.rs/handle/123456789/5347