Anti-melanoma effects of ingenanes isolated from Euphorbia species
2022
Authors:
Krstić, GordanaJadranin, Milka
Jovanović Stojanov, Sofija
Pešić, Milica
Tešević, Vele
Milosavljević, Slobodan
Document Type:
Conference object (Published version)
,
© 2023 North-Western Journal of Zoology University of Oradea
Metadata
Show full item recordAbstract:
In this research, from two species, E. palustris and E. lucida, four ingenane derivatives were isolated. Their anticancer effects were evaluated in the human melanoma – 518A2 cell line and compared with the effects of ingenolmebutate. Selectivity towards human melanoma cells was determined using normal human keratinocytes – HaCaT.
Keywords:
anticancer; isolation; plantsFunding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200168 (University of Belgrade, Faculty of Chemistry) (RS-MESTD-inst-2020-200168)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) (RS-MESTD-inst-2020-200026)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
In:
- 11th Conference on Medicinal and Aromatic Plants of Southeast European Countries 2022: CMAPSEEC 2022; 2022 Oct 6-10; Ohrid, Republic of North Macedonia. Skopje: Macedonian Pharmaceutical Association, 2022. p. 23-4. (Macedonian Pharmaceutical Bulletin; Vol. 68. Suppl. 2).