TY  - JOUR
AU  - Ransome, Emma
AU  - Hobbs, Faye
AU  - Jones, Scot
AU  - Coleman, C.M.
AU  - Harris, Danielle N.
AU  - Woodward, Guy
AU  - Bell, Thomas
AU  - Trew, Jahcub
AU  - Kolarević, Stoimir
AU  - Kračun-Kolarević, Margareta
AU  - Savolainen, Vincent
PY  - 2023
UR  - http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC9525188
UR  - https://linkinghub.elsevier.com/retrieve/pii/S004896972206260X
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5234
AB  - The presence of SARS-CoV-2 in untreated sewage has been confirmed in many countries but its incidence and infection risk in contaminated waters is poorly understood. The River Thames in the UK receives untreated sewage from 57 Combined Sewer Overflows (CSOs), with many discharging dozens of times per year. This study investigated if such discharges provide a pathway for environmental transmission of SARS-CoV-2. Samples of wastewater, surface water, and sediment collected close to six CSOs on the River Thames were assayed over eight months for SARS-CoV-2 RNA and infectious virus. Bivalves were also sampled as an indicator species of viral bioaccumulation. Sediment and water samples from the Danube and Sava rivers in Serbia, where raw sewage is also discharged in high volumes, were assayed as a positive control. No evidence of SARS-CoV-2 RNA or infectious virus was found in UK samples, in contrast to RNA positive samples from Serbia. Furthermore, this study shows that infectious SARS-CoV-2 inoculum is stable in Thames water and sediment for <3 days, while SARS-CoV-2 RNA is detectable for at least seven days. This indicates that dilution of wastewater likely limits environmental transmission, and that detection of viral RNA alone is not an indication of pathogen spillover.
PB  - Elsevier B.V.
T2  - Science of The Total Environment
T1  - Evaluating the transmission risk of SARS-CoV-2 from sewage pollution
IS  - Pt 2
VL  - 858
DO  - 10.1016/j.scitotenv.2022.159161
SP  - 159161
ER  - 

@article{
author = "Ransome, Emma and Hobbs, Faye and Jones, Scot and Coleman, C.M. and Harris, Danielle N. and Woodward, Guy and Bell, Thomas and Trew, Jahcub and Kolarević, Stoimir and Kračun-Kolarević, Margareta and Savolainen, Vincent",
year = "2023",
abstract = "The presence of SARS-CoV-2 in untreated sewage has been confirmed in many countries but its incidence and infection risk in contaminated waters is poorly understood. The River Thames in the UK receives untreated sewage from 57 Combined Sewer Overflows (CSOs), with many discharging dozens of times per year. This study investigated if such discharges provide a pathway for environmental transmission of SARS-CoV-2. Samples of wastewater, surface water, and sediment collected close to six CSOs on the River Thames were assayed over eight months for SARS-CoV-2 RNA and infectious virus. Bivalves were also sampled as an indicator species of viral bioaccumulation. Sediment and water samples from the Danube and Sava rivers in Serbia, where raw sewage is also discharged in high volumes, were assayed as a positive control. No evidence of SARS-CoV-2 RNA or infectious virus was found in UK samples, in contrast to RNA positive samples from Serbia. Furthermore, this study shows that infectious SARS-CoV-2 inoculum is stable in Thames water and sediment for <3 days, while SARS-CoV-2 RNA is detectable for at least seven days. This indicates that dilution of wastewater likely limits environmental transmission, and that detection of viral RNA alone is not an indication of pathogen spillover.",
publisher = "Elsevier B.V.",
journal = "Science of The Total Environment",
title = "Evaluating the transmission risk of SARS-CoV-2 from sewage pollution",
number = "Pt 2",
volume = "858",
doi = "10.1016/j.scitotenv.2022.159161",
pages = "159161"
}

Ransome, E., Hobbs, F., Jones, S., Coleman, C.M., Harris, D. N., Woodward, G., Bell, T., Trew, J., Kolarević, S., Kračun-Kolarević, M.,& Savolainen, V.. (2023). Evaluating the transmission risk of SARS-CoV-2 from sewage pollution. in Science of The Total Environment
Elsevier B.V.., 858(Pt 2), 159161.
https://doi.org/10.1016/j.scitotenv.2022.159161

Ransome E, Hobbs F, Jones S, Coleman C, Harris DN, Woodward G, Bell T, Trew J, Kolarević S, Kračun-Kolarević M, Savolainen V. Evaluating the transmission risk of SARS-CoV-2 from sewage pollution. in Science of The Total Environment. 2023;858(Pt 2):159161.
doi:10.1016/j.scitotenv.2022.159161 .

Ransome, Emma, Hobbs, Faye, Jones, Scot, Coleman, C.M., Harris, Danielle N., Woodward, Guy, Bell, Thomas, Trew, Jahcub, Kolarević, Stoimir, Kračun-Kolarević, Margareta, Savolainen, Vincent, "Evaluating the transmission risk of SARS-CoV-2 from sewage pollution" in Science of The Total Environment, 858, no. Pt 2 (2023):159161,
https://doi.org/10.1016/j.scitotenv.2022.159161 . .