TY  - JOUR
AU  - Mašković, Pavle
AU  - Dragišić Maksimović, Jelena
AU  - Maksimović, Vuk
AU  - Blagojević, Jelena
AU  - Vujošević, Mladen
AU  - Manojlović, Nedeljko T.
AU  - Radojković, Marija
AU  - Cvijović, Milica
AU  - Solujić, Slavica
PY  - 2012
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4675
AB  - The objective of this study was to evaluate the efficacy of the ethanolic extract of endemic plant Halacsya sendtneri in inhibiting the growing of the test fungi and bacteria as well as to determine its genotoxic potential and toxicity using the Allium anaphase-telophase assay. Minimum inhibitory concentrations (MIC) were determined for 15 indicator strains of pathogens, representing both bacteria and fungi. The highest susceptibility to the ethanolic extract of H. sendtneri was   exhibited by Pseudomonas glycinea (FSB4), (MIC=0.09 mg/ml) among the bacteria, and by Phialophora fastigiata (FSB81), (MIC=1.95 mg/ml) among the fungi. The composition of H. sendtneri extracts was also determined using HPLC analysis. Rosmarinic acid was found to be the dominant phenolic compound. The Allium anaphase-telophase genotoxicity assay revealed that the ethanolic extract of H. sendtneri at concentrations of 31.5 mg/l and below does not produce toxic or genotoxic effects. This is the first report of chemical constituents, genotoxic and antimicrobial activities of the endemic species, H.  sendtneri.
PB  - Warsaw: Versita
T2  - Central European Journal of Biology
T1  - Biological activities of phenolic compounds and ethanolic extract of Halacsya sendtneri(Boiss) Dőrfler
IS  - 2
VL  - 7
DO  - 10.2478/s11535-012-0021-8
SP  - 327
EP  - 333
ER  - 

@article{
author = "Mašković, Pavle and Dragišić Maksimović, Jelena and Maksimović, Vuk and Blagojević, Jelena and Vujošević, Mladen and Manojlović, Nedeljko T. and Radojković, Marija and Cvijović, Milica and Solujić, Slavica",
year = "2012",
abstract = "The objective of this study was to evaluate the efficacy of the ethanolic extract of endemic plant Halacsya sendtneri in inhibiting the growing of the test fungi and bacteria as well as to determine its genotoxic potential and toxicity using the Allium anaphase-telophase assay. Minimum inhibitory concentrations (MIC) were determined for 15 indicator strains of pathogens, representing both bacteria and fungi. The highest susceptibility to the ethanolic extract of H. sendtneri was   exhibited by Pseudomonas glycinea (FSB4), (MIC=0.09 mg/ml) among the bacteria, and by Phialophora fastigiata (FSB81), (MIC=1.95 mg/ml) among the fungi. The composition of H. sendtneri extracts was also determined using HPLC analysis. Rosmarinic acid was found to be the dominant phenolic compound. The Allium anaphase-telophase genotoxicity assay revealed that the ethanolic extract of H. sendtneri at concentrations of 31.5 mg/l and below does not produce toxic or genotoxic effects. This is the first report of chemical constituents, genotoxic and antimicrobial activities of the endemic species, H.  sendtneri.",
publisher = "Warsaw: Versita",
journal = "Central European Journal of Biology",
title = "Biological activities of phenolic compounds and ethanolic extract of Halacsya sendtneri(Boiss) Dőrfler",
number = "2",
volume = "7",
doi = "10.2478/s11535-012-0021-8",
pages = "327-333"
}

Mašković, P., Dragišić Maksimović, J., Maksimović, V., Blagojević, J., Vujošević, M., Manojlović, N. T., Radojković, M., Cvijović, M.,& Solujić, S.. (2012). Biological activities of phenolic compounds and ethanolic extract of Halacsya sendtneri(Boiss) Dőrfler. in Central European Journal of Biology
Warsaw: Versita., 7(2), 327-333.
https://doi.org/10.2478/s11535-012-0021-8

Mašković P, Dragišić Maksimović J, Maksimović V, Blagojević J, Vujošević M, Manojlović NT, Radojković M, Cvijović M, Solujić S. Biological activities of phenolic compounds and ethanolic extract of Halacsya sendtneri(Boiss) Dőrfler. in Central European Journal of Biology. 2012;7(2):327-333.
doi:10.2478/s11535-012-0021-8 .

Mašković, Pavle, Dragišić Maksimović, Jelena, Maksimović, Vuk, Blagojević, Jelena, Vujošević, Mladen, Manojlović, Nedeljko T., Radojković, Marija, Cvijović, Milica, Solujić, Slavica, "Biological activities of phenolic compounds and ethanolic extract of Halacsya sendtneri(Boiss) Dőrfler" in Central European Journal of Biology, 7, no. 2 (2012):327-333,
https://doi.org/10.2478/s11535-012-0021-8 . .