TY  - JOUR
AU  - Sinan, Kouadio Ibrahime
AU  - Zengin, Gokhan
AU  - Fiorentino, Antonio
AU  - Vuotto, Chiara
AU  - Mahomoodally, Mohamad Fawzi
AU  - Jugreet, Sharmeen
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
AU  - Etienne, Ouattara Katinan
AU  - Pereira, Catarina Guerreiro
AU  - Custódio, Luísa
AU  - Rengasamy, Kannan R.R.
AU  - D'Abrosca, Brigida
PY  - 2022
UR  - https://linkinghub.elsevier.com/retrieve/pii/S221242922200219X
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4985
AB  - Piliostigma thonningii (Fabaceae) is a versatile medicinal plant used as a traditional remedy, especially in African countries. In the present study, ethyl acetate, methanolic and water extracts of different parts of (fruits, leaves, stem barks) P. thonningii were evaluated for their bioactive contents, enzyme inhibitory, antioxidant and antimicrobial activities. Antioxidant potentials were also displayed in various methods like phosphomolybdenum assay (0.79–5.94 mmol TE/g), radical scavenging assays (DPPH: 20.39–471.28 mg TE/g; ABTS: 42.43–654.14 mg TE/g); reducing assays (CUPRAC: 102.98–1207.42 mg TE/g; FRAP: 45.30–656.25 mg TE/g) and metal chelating activity (2.55–22.32 mg EDTAE/g). In particular, the methanolic and water extracts showed better antioxidant potential. Except for a few, the extracts were also found to act as inhibitors of enzymes such as acetylcholinesterase (2.35–5.35 mg GALAE/g), butyrylcholinesterase (0.83–13.80 mg GALAE/g), tyrosinase (4.03–143.86 mg KAE/g), amylase (0.21–1.39 mmol ACAE/g) and glucosidase (3.52–7.13 mmol ACAE/g). Additionally, all the tested extracts possessed significant antibacterial (minimum inhibitory concentration (MIC) and minimum bactericidal concentration: 0.11–0.61 mg/ml) and antifungal (MIC and minimum fungicidal concentration: 0.04–0.61 mg/ml) effects. Indeed, the data garnered from the present study provides a bright scope for the advanced investigation on this particular plant possessing pharmacologically active traits.
PB  - Elsevier Ltd
T2  - Food Bioscience
T1  - Shining the spotlight on NMR metabolic profiling and bioactivities of different solvent extracts of Piliostigma thonningii
DO  - 10.1016/j.fbio.2022.101760
SP  - 101760
ER  - 

@article{
author = "Sinan, Kouadio Ibrahime and Zengin, Gokhan and Fiorentino, Antonio and Vuotto, Chiara and Mahomoodally, Mohamad Fawzi and Jugreet, Sharmeen and Glamočlija, Jasmina and Soković, Marina and Etienne, Ouattara Katinan and Pereira, Catarina Guerreiro and Custódio, Luísa and Rengasamy, Kannan R.R. and D'Abrosca, Brigida",
year = "2022",
abstract = "Piliostigma thonningii (Fabaceae) is a versatile medicinal plant used as a traditional remedy, especially in African countries. In the present study, ethyl acetate, methanolic and water extracts of different parts of (fruits, leaves, stem barks) P. thonningii were evaluated for their bioactive contents, enzyme inhibitory, antioxidant and antimicrobial activities. Antioxidant potentials were also displayed in various methods like phosphomolybdenum assay (0.79–5.94 mmol TE/g), radical scavenging assays (DPPH: 20.39–471.28 mg TE/g; ABTS: 42.43–654.14 mg TE/g); reducing assays (CUPRAC: 102.98–1207.42 mg TE/g; FRAP: 45.30–656.25 mg TE/g) and metal chelating activity (2.55–22.32 mg EDTAE/g). In particular, the methanolic and water extracts showed better antioxidant potential. Except for a few, the extracts were also found to act as inhibitors of enzymes such as acetylcholinesterase (2.35–5.35 mg GALAE/g), butyrylcholinesterase (0.83–13.80 mg GALAE/g), tyrosinase (4.03–143.86 mg KAE/g), amylase (0.21–1.39 mmol ACAE/g) and glucosidase (3.52–7.13 mmol ACAE/g). Additionally, all the tested extracts possessed significant antibacterial (minimum inhibitory concentration (MIC) and minimum bactericidal concentration: 0.11–0.61 mg/ml) and antifungal (MIC and minimum fungicidal concentration: 0.04–0.61 mg/ml) effects. Indeed, the data garnered from the present study provides a bright scope for the advanced investigation on this particular plant possessing pharmacologically active traits.",
publisher = "Elsevier Ltd",
journal = "Food Bioscience",
title = "Shining the spotlight on NMR metabolic profiling and bioactivities of different solvent extracts of Piliostigma thonningii",
doi = "10.1016/j.fbio.2022.101760",
pages = "101760"
}

Sinan, K. I., Zengin, G., Fiorentino, A., Vuotto, C., Mahomoodally, M. F., Jugreet, S., Glamočlija, J., Soković, M., Etienne, O. K., Pereira, C. G., Custódio, L., Rengasamy, K. R.R.,& D'Abrosca, B.. (2022). Shining the spotlight on NMR metabolic profiling and bioactivities of different solvent extracts of Piliostigma thonningii. in Food Bioscience
Elsevier Ltd., 101760.
https://doi.org/10.1016/j.fbio.2022.101760

Sinan KI, Zengin G, Fiorentino A, Vuotto C, Mahomoodally MF, Jugreet S, Glamočlija J, Soković M, Etienne OK, Pereira CG, Custódio L, Rengasamy KR, D'Abrosca B. Shining the spotlight on NMR metabolic profiling and bioactivities of different solvent extracts of Piliostigma thonningii. in Food Bioscience. 2022;:101760.
doi:10.1016/j.fbio.2022.101760 .

Sinan, Kouadio Ibrahime, Zengin, Gokhan, Fiorentino, Antonio, Vuotto, Chiara, Mahomoodally, Mohamad Fawzi, Jugreet, Sharmeen, Glamočlija, Jasmina, Soković, Marina, Etienne, Ouattara Katinan, Pereira, Catarina Guerreiro, Custódio, Luísa, Rengasamy, Kannan R.R., D'Abrosca, Brigida, "Shining the spotlight on NMR metabolic profiling and bioactivities of different solvent extracts of Piliostigma thonningii" in Food Bioscience (2022):101760,
https://doi.org/10.1016/j.fbio.2022.101760 . .