TY  - JOUR
AU  - Kaluđerović, Milena R.
AU  - Mojić, Marija
AU  - Gómez-Ruiz,  Santiago
AU  - Mijatović, Sanja
AU  - Maksimović-Ivanić, Danijela
PY  - 2016
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3826
AB  - In vitro antitumor activity of various organogallium(III) complexes (1-8) has been tested against CT26CL25, HCT116, SW480 colon cancer cell lines. CV and MTT assays were used to assess on the antiproliferative effect of investigated organogallium(III) complexes. From the investigated complexes, the most active was found to be tetranuclear compound 8 against CT26CL25 cells. Flow cytometric analysis of the CT26CL25 cells upon the treatment with 8 was performed in order to determine the role of apoptosis, caspase activation, autophagy and proliferation rate on the cell death caused with this compound. Results indicate cytotoxic potential of the tetranuclear complex 8 by inducing caspase independent apoptosis and blocking most of the cells before first division.
PB  - Sharjah: Bentham Science Publishers
T2  - Anticancer Agents Med Chem
T1  - Anticancer Activity of Organogallium(III) Complexes in Colon Cancer Cells
IS  - 3
VL  - 16
DO  - 10.2174/1871520615666151007160319
SP  - 359
EP  - 364
ER  - 

@article{
author = "Kaluđerović, Milena R. and Mojić, Marija and Gómez-Ruiz,  Santiago and Mijatović, Sanja and Maksimović-Ivanić, Danijela",
year = "2016",
abstract = "In vitro antitumor activity of various organogallium(III) complexes (1-8) has been tested against CT26CL25, HCT116, SW480 colon cancer cell lines. CV and MTT assays were used to assess on the antiproliferative effect of investigated organogallium(III) complexes. From the investigated complexes, the most active was found to be tetranuclear compound 8 against CT26CL25 cells. Flow cytometric analysis of the CT26CL25 cells upon the treatment with 8 was performed in order to determine the role of apoptosis, caspase activation, autophagy and proliferation rate on the cell death caused with this compound. Results indicate cytotoxic potential of the tetranuclear complex 8 by inducing caspase independent apoptosis and blocking most of the cells before first division.",
publisher = "Sharjah: Bentham Science Publishers",
journal = "Anticancer Agents Med Chem",
title = "Anticancer Activity of Organogallium(III) Complexes in Colon Cancer Cells",
number = "3",
volume = "16",
doi = "10.2174/1871520615666151007160319",
pages = "359-364"
}

Kaluđerović, M. R., Mojić, M., Gómez-Ruiz,  ., Mijatović, S.,& Maksimović-Ivanić, D.. (2016). Anticancer Activity of Organogallium(III) Complexes in Colon Cancer Cells. in Anticancer Agents Med Chem
Sharjah: Bentham Science Publishers., 16(3), 359-364.
https://doi.org/10.2174/1871520615666151007160319

Kaluđerović MR, Mojić M, Gómez-Ruiz  , Mijatović S, Maksimović-Ivanić D. Anticancer Activity of Organogallium(III) Complexes in Colon Cancer Cells. in Anticancer Agents Med Chem. 2016;16(3):359-364.
doi:10.2174/1871520615666151007160319 .

Kaluđerović, Milena R., Mojić, Marija, Gómez-Ruiz,  Santiago, Mijatović, Sanja, Maksimović-Ivanić, Danijela, "Anticancer Activity of Organogallium(III) Complexes in Colon Cancer Cells" in Anticancer Agents Med Chem, 16, no. 3 (2016):359-364,
https://doi.org/10.2174/1871520615666151007160319 . .