TY  - JOUR
AU  - Kostić, Marina
AU  - Ivanov, Marija
AU  - Sanković Babić, Snežana
AU  - Tepavčević, Zvezdana
AU  - Radanović, Oliver
AU  - Soković, Marina
AU  - Ćirić, Ana
PY  - 2022
UR  - https://www.mdpi.com/2079-6382/11/12/1747
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5353
AB  - Chronic tonsillitis (CT) is a global health issue which can impair patient’s quality of life and has an important socioeconomic impact due to the nonrational use of antibiotics, increased antimicrobial resistance and frequent need for surgical treatment. In order to isolate and identify the causing agents of CT, a total of 79 postoperative palatine and adenoid tissue samples were obtained from the ENT Clinic, KBC Zvezdara, Belgrade, Serbia. Culture identification was performed by MALDI-TOF MS and the Staphylococcus aureus isolates were tested for biofilm forming capability and antibiotic susceptibility. Additionally, a histological examination of palatine and adenoid tissue was performed in order to detect the presence of CT-causing bacteria. The slight majority of participants were females with median age of 28 years for adult patients (group I) and 6 years for children (group II). Analysis of the incidence of bacteria isolated from tissue samples in both groups showed the highest prevalence of S. aureus, Streptococcus oralis and Streptococcus parasanquinis. In addition to interfollicular hyperplasia, colonies of species S. aureus were detected in histological material. The presence of biofilm might be the reason for the recurrence of infection. Therefore, searching for a new treatment of CT is of great importance.
PB  - Basel: MDPI
T2  - Antibiotics
T1  - Analysis of Tonsil Tissues from Patients Diagnosed with Chronic Tonsillitis—Microbiological Profile, Biofilm-Forming Capacity and Histology
IS  - 12
VL  - 11
DO  - 10.3390/antibiotics11121747
SP  - 1747
ER  - 

@article{
author = "Kostić, Marina and Ivanov, Marija and Sanković Babić, Snežana and Tepavčević, Zvezdana and Radanović, Oliver and Soković, Marina and Ćirić, Ana",
year = "2022",
abstract = "Chronic tonsillitis (CT) is a global health issue which can impair patient’s quality of life and has an important socioeconomic impact due to the nonrational use of antibiotics, increased antimicrobial resistance and frequent need for surgical treatment. In order to isolate and identify the causing agents of CT, a total of 79 postoperative palatine and adenoid tissue samples were obtained from the ENT Clinic, KBC Zvezdara, Belgrade, Serbia. Culture identification was performed by MALDI-TOF MS and the Staphylococcus aureus isolates were tested for biofilm forming capability and antibiotic susceptibility. Additionally, a histological examination of palatine and adenoid tissue was performed in order to detect the presence of CT-causing bacteria. The slight majority of participants were females with median age of 28 years for adult patients (group I) and 6 years for children (group II). Analysis of the incidence of bacteria isolated from tissue samples in both groups showed the highest prevalence of S. aureus, Streptococcus oralis and Streptococcus parasanquinis. In addition to interfollicular hyperplasia, colonies of species S. aureus were detected in histological material. The presence of biofilm might be the reason for the recurrence of infection. Therefore, searching for a new treatment of CT is of great importance.",
publisher = "Basel: MDPI",
journal = "Antibiotics",
title = "Analysis of Tonsil Tissues from Patients Diagnosed with Chronic Tonsillitis—Microbiological Profile, Biofilm-Forming Capacity and Histology",
number = "12",
volume = "11",
doi = "10.3390/antibiotics11121747",
pages = "1747"
}

Kostić, M., Ivanov, M., Sanković Babić, S., Tepavčević, Z., Radanović, O., Soković, M.,& Ćirić, A.. (2022). Analysis of Tonsil Tissues from Patients Diagnosed with Chronic Tonsillitis—Microbiological Profile, Biofilm-Forming Capacity and Histology. in Antibiotics
Basel: MDPI., 11(12), 1747.
https://doi.org/10.3390/antibiotics11121747

Kostić M, Ivanov M, Sanković Babić S, Tepavčević Z, Radanović O, Soković M, Ćirić A. Analysis of Tonsil Tissues from Patients Diagnosed with Chronic Tonsillitis—Microbiological Profile, Biofilm-Forming Capacity and Histology. in Antibiotics. 2022;11(12):1747.
doi:10.3390/antibiotics11121747 .

Kostić, Marina, Ivanov, Marija, Sanković Babić, Snežana, Tepavčević, Zvezdana, Radanović, Oliver, Soković, Marina, Ćirić, Ana, "Analysis of Tonsil Tissues from Patients Diagnosed with Chronic Tonsillitis—Microbiological Profile, Biofilm-Forming Capacity and Histology" in Antibiotics, 11, no. 12 (2022):1747,
https://doi.org/10.3390/antibiotics11121747 . .