TY  - JOUR
AU  - Zec, Manja
AU  - Debeljak Martačić, Jasmina
AU  - Ranković, Slavica
AU  - Pokimica, Biljana
AU  - Tomić, Mirko
AU  - Ignjatović, Đurđica
AU  - Glibetić, Maria
AU  - Popović, Tamara
PY  - 2017
UR  - http://www.degruyter.com/view/j/acve.2017.67.issue-1/acve-2017-0010/acve-2017-0010.xml
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2731
AB  - A nutritional placebo-controlled study was performed in Wistar rats in order to investigate the effects of 5-weeks aronia juice consumption towards fatty acid (FA) composition of phospholipids in the plasma and liver, as well as plasma glucose (Glu) and cholesterol levels. The animals were divided into 3 groups of 8 animals each, and randomized to receive either the full polyphenol dose of Aronia melanocarpa juice (AMJ), 4 times less polyphenol dose (1/4-AMJ) or polyphenol-lacking placebo beverage (PLB). Each group of 8 male adult Wistar rats received the liquid ad libitum. AMJ decreased the levels of low-density lipoprotein (LDL) (P < 0.05) vs. PLB. AMJ increased dihomo-γ-linoleic acid (DGLA, 20:3n-6) (P < 0.05) and decreased arachidonic acid content (AA, 20:4n-6) (P < 0.05) vs. PLB in liver phospholipids. AMJ significantly increased monounsaturated fatty acids (MUFA) levels both in the liver (P < 0.05) and plasma (P < 0.05). Both aronia juice doses elevated the levels of beneficial n-3 polyunsaturated fatty acids (PUFA) in the plasma and liver. There was a dose-dependent, significant increase (P < 0.001) in cis-vaccenic acid (VA, 18:1n-7) in phospholipids in the plasma and liver. Our results indicate favorable effects of aronia juice intake on lipid parameters in Wistar rats. These findings suggest the potential of aronia dietary intake in cardiometabolic diseases primary prevention strategies in the human population.
T2  - Acta Veterinaria
T1  - Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats
IS  - 1
VL  - 67
DO  - 10.1515/acve-2017-0010
SP  - 107
EP  - 120
ER  - 

@article{
author = "Zec, Manja and Debeljak Martačić, Jasmina and Ranković, Slavica and Pokimica, Biljana and Tomić, Mirko and Ignjatović, Đurđica and Glibetić, Maria and Popović, Tamara",
year = "2017",
abstract = "A nutritional placebo-controlled study was performed in Wistar rats in order to investigate the effects of 5-weeks aronia juice consumption towards fatty acid (FA) composition of phospholipids in the plasma and liver, as well as plasma glucose (Glu) and cholesterol levels. The animals were divided into 3 groups of 8 animals each, and randomized to receive either the full polyphenol dose of Aronia melanocarpa juice (AMJ), 4 times less polyphenol dose (1/4-AMJ) or polyphenol-lacking placebo beverage (PLB). Each group of 8 male adult Wistar rats received the liquid ad libitum. AMJ decreased the levels of low-density lipoprotein (LDL) (P < 0.05) vs. PLB. AMJ increased dihomo-γ-linoleic acid (DGLA, 20:3n-6) (P < 0.05) and decreased arachidonic acid content (AA, 20:4n-6) (P < 0.05) vs. PLB in liver phospholipids. AMJ significantly increased monounsaturated fatty acids (MUFA) levels both in the liver (P < 0.05) and plasma (P < 0.05). Both aronia juice doses elevated the levels of beneficial n-3 polyunsaturated fatty acids (PUFA) in the plasma and liver. There was a dose-dependent, significant increase (P < 0.001) in cis-vaccenic acid (VA, 18:1n-7) in phospholipids in the plasma and liver. Our results indicate favorable effects of aronia juice intake on lipid parameters in Wistar rats. These findings suggest the potential of aronia dietary intake in cardiometabolic diseases primary prevention strategies in the human population.",
journal = "Acta Veterinaria",
title = "Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats",
number = "1",
volume = "67",
doi = "10.1515/acve-2017-0010",
pages = "107-120"
}

Zec, M., Debeljak Martačić, J., Ranković, S., Pokimica, B., Tomić, M., Ignjatović, Đ., Glibetić, M.,& Popović, T.. (2017). Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats. in Acta Veterinaria, 67(1), 107-120.
https://doi.org/10.1515/acve-2017-0010

Zec M, Debeljak Martačić J, Ranković S, Pokimica B, Tomić M, Ignjatović Đ, Glibetić M, Popović T. Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats. in Acta Veterinaria. 2017;67(1):107-120.
doi:10.1515/acve-2017-0010 .

Zec, Manja, Debeljak Martačić, Jasmina, Ranković, Slavica, Pokimica, Biljana, Tomić, Mirko, Ignjatović, Đurđica, Glibetić, Maria, Popović, Tamara, "Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats" in Acta Veterinaria, 67, no. 1 (2017):107-120,
https://doi.org/10.1515/acve-2017-0010 . .

TY  - CONF
AU  - Ranković, Slavica
AU  - Popović, Tamara
AU  - Debeljak Martačić, Jasmina
AU  - Pokimica, Biljana
AU  - Petrović-Oggiano, Gordana
AU  - Tomić, Mirko
AU  - Ignjatović, Đurđica
AU  - Tovilović-Kovačević, Gordana
AU  - Glibetić, Marija
PY  - 2016
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6770
AB  - Gender related differences in fatty acid composition of different lipid classes are well established. Changes in the proportions of specific long-chain PUFA in membrane phospholipids can alter cell and tissue function.
	The aim of our study was to examine the effects of different diets on phospholipids fatty acids composition in rat's liver of both sexes and to compare them.
	Adult Wistar rats of both sexes (n=8, 300g+5) were used in this study. Animals were fed with different type of diets (standard, fish-based and milk- based). The phospholipids fatty acid composition of liver was determined by Gas Chromatography using Shimadzu GC.
	Diet changes the ratio of SFA, MUFA and PUFA but the effects were sex specific. Milk based diet lowered the amount of SFA (p<0.05) and elevated the ratio of MUFA (ANOVA diet effect, p<0.001) in males (ANOVA sex effect p<0.001, and interaction S x D, p<0.05), and PUFA, in females (ANOVA sex effect p<0.05, and diet effect p<0.05) comparing to standard diet. Milk based diet decreased n-3 (p<0.001), and increased n-6 (p<0.001) and n-6/n-3 (p<0.001) ratio in males comparing to the other type of diets. On the other hand, in females, fish based diet increased n-3 (p<0.001), decreased n-6 (p<0.001) and n-6/n-3 ratio (p<0.001) comparing to standard and milk based diets (ANOVA diet effect, p< 0.001, S x D effect, p<0.001, Tukey's post hoc).
	Our results showed that each type of diet changes the composition of lipids and their ratio in the liver of rats. Fish based diet improving EPA and DHA fatty acid profiles and overall PUFA and has beneficial health effect.
PB  - Belgrade: Serbian Nutrition Society
C3  - Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia
T1  - Effects of different types of diet on liver fatty acids profiles in Wistar rats
SP  - 277
ER  - 

@conference{
author = "Ranković, Slavica and Popović, Tamara and Debeljak Martačić, Jasmina and Pokimica, Biljana and Petrović-Oggiano, Gordana and Tomić, Mirko and Ignjatović, Đurđica and Tovilović-Kovačević, Gordana and Glibetić, Marija",
year = "2016",
abstract = "Gender related differences in fatty acid composition of different lipid classes are well established. Changes in the proportions of specific long-chain PUFA in membrane phospholipids can alter cell and tissue function.
	The aim of our study was to examine the effects of different diets on phospholipids fatty acids composition in rat's liver of both sexes and to compare them.
	Adult Wistar rats of both sexes (n=8, 300g+5) were used in this study. Animals were fed with different type of diets (standard, fish-based and milk- based). The phospholipids fatty acid composition of liver was determined by Gas Chromatography using Shimadzu GC.
	Diet changes the ratio of SFA, MUFA and PUFA but the effects were sex specific. Milk based diet lowered the amount of SFA (p<0.05) and elevated the ratio of MUFA (ANOVA diet effect, p<0.001) in males (ANOVA sex effect p<0.001, and interaction S x D, p<0.05), and PUFA, in females (ANOVA sex effect p<0.05, and diet effect p<0.05) comparing to standard diet. Milk based diet decreased n-3 (p<0.001), and increased n-6 (p<0.001) and n-6/n-3 (p<0.001) ratio in males comparing to the other type of diets. On the other hand, in females, fish based diet increased n-3 (p<0.001), decreased n-6 (p<0.001) and n-6/n-3 ratio (p<0.001) comparing to standard and milk based diets (ANOVA diet effect, p< 0.001, S x D effect, p<0.001, Tukey's post hoc).
	Our results showed that each type of diet changes the composition of lipids and their ratio in the liver of rats. Fish based diet improving EPA and DHA fatty acid profiles and overall PUFA and has beneficial health effect.",
publisher = "Belgrade: Serbian Nutrition Society",
journal = "Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia",
title = "Effects of different types of diet on liver fatty acids profiles in Wistar rats",
pages = "277"
}

Ranković, S., Popović, T., Debeljak Martačić, J., Pokimica, B., Petrović-Oggiano, G., Tomić, M., Ignjatović, Đ., Tovilović-Kovačević, G.,& Glibetić, M.. (2016). Effects of different types of diet on liver fatty acids profiles in Wistar rats. in Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia
Belgrade: Serbian Nutrition Society., 277.

Ranković S, Popović T, Debeljak Martačić J, Pokimica B, Petrović-Oggiano G, Tomić M, Ignjatović Đ, Tovilović-Kovačević G, Glibetić M. Effects of different types of diet on liver fatty acids profiles in Wistar rats. in Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia. 2016;:277..

Ranković, Slavica, Popović, Tamara, Debeljak Martačić, Jasmina, Pokimica, Biljana, Petrović-Oggiano, Gordana, Tomić, Mirko, Ignjatović, Đurđica, Tovilović-Kovačević, Gordana, Glibetić, Marija, "Effects of different types of diet on liver fatty acids profiles in Wistar rats" in Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia (2016):277.