TY  - JOUR
AU  - Baur, Julian
AU  - Koppik, Mareike
AU  - Savković, Uroš
AU  - Đorđević, Mirko
AU  - Stojković, Biljana
AU  - Berger, David
PY  - 2024
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6820
AB  - An often-overlooked aspect of life-history optimization is the allocation of resources to protect the germline and secure safe transmission of genetic information. While failure to do so renders significant fitness consequences in future generations, germline maintenance comes with substantial costs. Thus, germline allocation should trade off with other life-history decisions and be optimized in accordance with an organism’s reproductive schedule. Here, we tested this hypothesis by studying germline maintenance in lines of seed beetle, selected for early (E) or late (L) reproduction for 350 and 240 generations, respectively. Female animals provide maintenance and screening of male gametes in their reproductive tract and oocytes. Here, we reveal the ability of young and aged E- and L-females to provide this form of germline maintenance by mating them to males with ejaculates with artificially elevated levels of protein and DNA damage. We find that germline maintenance in E-females peaks at young age and then declines, while the opposite is true for L-females, in accordance with the age of reproduction in the respective regime. These findings identify the central role of allocation to secure germline integrity in life-history evolution and highlight how females can play a crucial role in mitigating the effects of male germline decisions on mutation rate and offspring quality.
PB  - The Royal Society
T2  - Proceedings of the Royal Society. B: Biological Sciences
T1  - Coevolution of longevity and femalegermline maintenance
IS  - 2024
VL  - 291
DO  - 10.1098/rspb.2024.0532
SP  - 20240532
ER  - 

@article{
author = "Baur, Julian and Koppik, Mareike and Savković, Uroš and Đorđević, Mirko and Stojković, Biljana and Berger, David",
year = "2024",
abstract = "An often-overlooked aspect of life-history optimization is the allocation of resources to protect the germline and secure safe transmission of genetic information. While failure to do so renders significant fitness consequences in future generations, germline maintenance comes with substantial costs. Thus, germline allocation should trade off with other life-history decisions and be optimized in accordance with an organism’s reproductive schedule. Here, we tested this hypothesis by studying germline maintenance in lines of seed beetle, selected for early (E) or late (L) reproduction for 350 and 240 generations, respectively. Female animals provide maintenance and screening of male gametes in their reproductive tract and oocytes. Here, we reveal the ability of young and aged E- and L-females to provide this form of germline maintenance by mating them to males with ejaculates with artificially elevated levels of protein and DNA damage. We find that germline maintenance in E-females peaks at young age and then declines, while the opposite is true for L-females, in accordance with the age of reproduction in the respective regime. These findings identify the central role of allocation to secure germline integrity in life-history evolution and highlight how females can play a crucial role in mitigating the effects of male germline decisions on mutation rate and offspring quality.",
publisher = "The Royal Society",
journal = "Proceedings of the Royal Society. B: Biological Sciences",
title = "Coevolution of longevity and femalegermline maintenance",
number = "2024",
volume = "291",
doi = "10.1098/rspb.2024.0532",
pages = "20240532"
}

Baur, J., Koppik, M., Savković, U., Đorđević, M., Stojković, B.,& Berger, D.. (2024). Coevolution of longevity and femalegermline maintenance. in Proceedings of the Royal Society. B: Biological Sciences
The Royal Society., 291(2024), 20240532.
https://doi.org/10.1098/rspb.2024.0532

Baur J, Koppik M, Savković U, Đorđević M, Stojković B, Berger D. Coevolution of longevity and femalegermline maintenance. in Proceedings of the Royal Society. B: Biological Sciences. 2024;291(2024):20240532.
doi:10.1098/rspb.2024.0532 .

Baur, Julian, Koppik, Mareike, Savković, Uroš, Đorđević, Mirko, Stojković, Biljana, Berger, David, "Coevolution of longevity and femalegermline maintenance" in Proceedings of the Royal Society. B: Biological Sciences, 291, no. 2024 (2024):20240532,
https://doi.org/10.1098/rspb.2024.0532 . .

TY  - JOUR
AU  - Martinossi-Allibert, Ivain
AU  - Savković, Uroš
AU  - Đorđević, Mirko
AU  - Arnqvist, Göran
AU  - Stojković, Biljana
AU  - Berger, David
PY  - 2018
UR  - http://doi.wiley.com/10.1111/evo.13412
UR  - http://www.ncbi.nlm.nih.gov/pubmed/29238970
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2963
AB  - Whether sexual selection generally promotes or impedes population persistence remains an open question. Intralocus sexual conflict (IaSC) can render sexual selection in males detrimental to the population by increasing the frequency of alleles with positive effects on male reproductive success but negative effects on female fecundity. Recent modeling based on fitness landscape theory, however, indicates that the relative impact of IaSC may be reduced in maladapted populations and that sexual selection therefore might promote adaptation when it is most needed. Here, we test this prediction using bean beetles that had undergone 80 generations of experimental evolution on two alternative host plants. We isolated and assessed the effect of maladaptation on sex-specific strengths of selection and IaSC by cross-rearing the two experimental evolution regimes on the alternative hosts and estimating within-population genetic (co)variance for fitness in males and females. Two key predictions were upheld: males generally experienced stronger selection compared to females and maladaptation increased selection in females. However, maladaptation consistently decreased male-bias in the strength of selection and IaSC was not reduced in maladapted populations. These findings imply that sexual selection can be disrupted in stressful environmental conditions, thus reducing one of the potential benefits of sexual reproduction in maladapted populations.
T2  - Evolution
T1  - The consequences of sexual selection in well-adapted and maladapted populations of bean beetles.
DO  - 10.1111/evo.13412
ER  - 

@article{
author = "Martinossi-Allibert, Ivain and Savković, Uroš and Đorđević, Mirko and Arnqvist, Göran and Stojković, Biljana and Berger, David",
year = "2018",
abstract = "Whether sexual selection generally promotes or impedes population persistence remains an open question. Intralocus sexual conflict (IaSC) can render sexual selection in males detrimental to the population by increasing the frequency of alleles with positive effects on male reproductive success but negative effects on female fecundity. Recent modeling based on fitness landscape theory, however, indicates that the relative impact of IaSC may be reduced in maladapted populations and that sexual selection therefore might promote adaptation when it is most needed. Here, we test this prediction using bean beetles that had undergone 80 generations of experimental evolution on two alternative host plants. We isolated and assessed the effect of maladaptation on sex-specific strengths of selection and IaSC by cross-rearing the two experimental evolution regimes on the alternative hosts and estimating within-population genetic (co)variance for fitness in males and females. Two key predictions were upheld: males generally experienced stronger selection compared to females and maladaptation increased selection in females. However, maladaptation consistently decreased male-bias in the strength of selection and IaSC was not reduced in maladapted populations. These findings imply that sexual selection can be disrupted in stressful environmental conditions, thus reducing one of the potential benefits of sexual reproduction in maladapted populations.",
journal = "Evolution",
title = "The consequences of sexual selection in well-adapted and maladapted populations of bean beetles.",
doi = "10.1111/evo.13412"
}

Martinossi-Allibert, I., Savković, U., Đorđević, M., Arnqvist, G., Stojković, B.,& Berger, D.. (2018). The consequences of sexual selection in well-adapted and maladapted populations of bean beetles.. in Evolution.
https://doi.org/10.1111/evo.13412

Martinossi-Allibert I, Savković U, Đorđević M, Arnqvist G, Stojković B, Berger D. The consequences of sexual selection in well-adapted and maladapted populations of bean beetles.. in Evolution. 2018;.
doi:10.1111/evo.13412 .

Martinossi-Allibert, Ivain, Savković, Uroš, Đorđević, Mirko, Arnqvist, Göran, Stojković, Biljana, Berger, David, "The consequences of sexual selection in well-adapted and maladapted populations of bean beetles." in Evolution (2018),
https://doi.org/10.1111/evo.13412 . .