Miletić, Srdjan

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  • Miletić, Srdjan (2)
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Redox properties of transitional milk from mothers of preterm infants.

Minić, Simeon; Ješić, Miloš; Đurović, Dijana; Miletić, Srdjan; Lugonja, Nikoleta; Marinković, Vesna; Nikolić-Kokić, Aleksandra; Spasić, Snežana; Vrvić, Miroslav M

(2018)

TY  - JOUR
AU  - Minić, Simeon
AU  - Ješić, Miloš
AU  - Đurović, Dijana
AU  - Miletić, Srdjan
AU  - Lugonja, Nikoleta
AU  - Marinković, Vesna
AU  - Nikolić-Kokić, Aleksandra
AU  - Spasić, Snežana
AU  - Vrvić, Miroslav M
PY  - 2018
UR  - http://doi.wiley.com/10.1111/jpc.13676
UR  - http://www.ncbi.nlm.nih.gov/pubmed/28791778
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2997
AB  - AIM There is a discrepancy between the amount of transitional milk produced by mothers of preterm infants and the low capacity of premature infants to consume it. This milk can be used in milk banks, but previous studies found that there are large variations in the level of host-defence proteins in individual samples of milk from mothers of premature infants, which implies that large individual variations in antioxidative defence composition are also possible. METHODS Milk samples were collected from 20 healthy mothers of preterm infants. We determined the values for non-enzymatic antioxidative capacity parameters (oxygen radical absorbance capacity (ORAC)), static oxidation-reduction potential (ORP), activities of antioxidant defence enzymes and the amount of vitamin C in whole milk, skim and whey fractions of transitional milk. RESULTS The main low-molecular-weight antioxidant in transitional milk is vitamin C and most of it is contained in whey. ORAC is higher in whole transitional milk than in skim milk and whey, and ORP is lower in whole transitional milk than that in skim milk and whey. Antioxidative enzyme activities are similar in all individual samples of transitional milk from mothers of preterm infants. CONCLUSIONS Our results indicate that transitional milk of mothers of preterm infants shows slow individual variations in antioxidative defence composition; therefore, it can be used in human milk banks.
T2  - Journal of Paediatrics and Child Health
T1  - Redox properties of transitional milk from mothers of preterm infants.
IS  - 2
VL  - 54
DO  - 10.1111/jpc.13676
SP  - 160
EP  - 164
ER  - 
@article{
author = "Minić, Simeon and Ješić, Miloš and Đurović, Dijana and Miletić, Srdjan and Lugonja, Nikoleta and Marinković, Vesna and Nikolić-Kokić, Aleksandra and Spasić, Snežana and Vrvić, Miroslav M",
year = "2018",
abstract = "AIM There is a discrepancy between the amount of transitional milk produced by mothers of preterm infants and the low capacity of premature infants to consume it. This milk can be used in milk banks, but previous studies found that there are large variations in the level of host-defence proteins in individual samples of milk from mothers of premature infants, which implies that large individual variations in antioxidative defence composition are also possible. METHODS Milk samples were collected from 20 healthy mothers of preterm infants. We determined the values for non-enzymatic antioxidative capacity parameters (oxygen radical absorbance capacity (ORAC)), static oxidation-reduction potential (ORP), activities of antioxidant defence enzymes and the amount of vitamin C in whole milk, skim and whey fractions of transitional milk. RESULTS The main low-molecular-weight antioxidant in transitional milk is vitamin C and most of it is contained in whey. ORAC is higher in whole transitional milk than in skim milk and whey, and ORP is lower in whole transitional milk than that in skim milk and whey. Antioxidative enzyme activities are similar in all individual samples of transitional milk from mothers of preterm infants. CONCLUSIONS Our results indicate that transitional milk of mothers of preterm infants shows slow individual variations in antioxidative defence composition; therefore, it can be used in human milk banks.",
journal = "Journal of Paediatrics and Child Health",
title = "Redox properties of transitional milk from mothers of preterm infants.",
number = "2",
volume = "54",
doi = "10.1111/jpc.13676",
pages = "160-164"
}
Minić, S., Ješić, M., Đurović, D., Miletić, S., Lugonja, N., Marinković, V., Nikolić-Kokić, A., Spasić, S.,& Vrvić, M. M.. (2018). Redox properties of transitional milk from mothers of preterm infants.. in Journal of Paediatrics and Child Health, 54(2), 160-164.
https://doi.org/10.1111/jpc.13676
Minić S, Ješić M, Đurović D, Miletić S, Lugonja N, Marinković V, Nikolić-Kokić A, Spasić S, Vrvić MM. Redox properties of transitional milk from mothers of preterm infants.. in Journal of Paediatrics and Child Health. 2018;54(2):160-164.
doi:10.1111/jpc.13676 .
Minić, Simeon, Ješić, Miloš, Đurović, Dijana, Miletić, Srdjan, Lugonja, Nikoleta, Marinković, Vesna, Nikolić-Kokić, Aleksandra, Spasić, Snežana, Vrvić, Miroslav M, "Redox properties of transitional milk from mothers of preterm infants." in Journal of Paediatrics and Child Health, 54, no. 2 (2018):160-164,
https://doi.org/10.1111/jpc.13676 . .
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Apple pectin-derived oligosaccharides produce carbon dioxide radical anion in Fenton reaction and prevent growth of Escherichia coli and Staphylococcus aureus

Martinov, Jelena; Krstić, Miodrag; Spasić, Snežana; Miletić, Srdjan; Stefanović-Kojić, Jovana; Nikolić-Kokić, Aleksandra; Blagojević, Duško; Spasojević, Ivan; Spasić, Mihajlo

(2017)

TY  - JOUR
AU  - Martinov, Jelena
AU  - Krstić, Miodrag
AU  - Spasić, Snežana
AU  - Miletić, Srdjan
AU  - Stefanović-Kojić, Jovana
AU  - Nikolić-Kokić, Aleksandra
AU  - Blagojević, Duško
AU  - Spasojević, Ivan
AU  - Spasić, Mihajlo
PY  - 2017
UR  - http://linkinghub.elsevier.com/retrieve/pii/S0963996917304787
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2843
AB  - Pectin is the main soluble fiber in apples or citruses. It may be fermented by gut microbiota to metabolites showing local intestinal and systemic effects. A wide range of beneficial effects of dietary pectin includes impacts on the redox milieu and microbiota profile. We prepared pectin-derived oligosaccharides (apple (APDO) and citrus) and polygalacturonic acid-derived oligosaccharides, using alkaline hydrolysis by hydrogen peroxide, and analyzed them by Fourier Transform Infrared spectrometry. Furthermore, we analyzed the effects of pectin-derived oligosaccharides on hydroxyl radical (HO)-generating Fenton reaction using electron paramagnetic resonance spin-trapping spectroscopy, and the effects on the growth of Escherichia coli and Staphylococcus aureus in the presence of dietary-relevant HO-generating system (iron+ascorbate). The oligosaccharides react with HO radical to produce carbon dioxide radical anion (CO 2 - ). A comparative analysis showed that APDO has the most prominent bacteriostatic effect. This might be at least partially related to the higher capacity of APDO to produce CO 2 - , which specifically targets proteins and appears to have a longer lifetime and larger diffusion radius in biological systems compared to HO.
T2  - Food Research International
T1  - Apple pectin-derived oligosaccharides produce carbon dioxide radical anion in Fenton reaction and prevent growth of Escherichia coli and Staphylococcus aureus
DO  - 10.1016/j.foodres.2017.08.040
ER  - 
@article{
author = "Martinov, Jelena and Krstić, Miodrag and Spasić, Snežana and Miletić, Srdjan and Stefanović-Kojić, Jovana and Nikolić-Kokić, Aleksandra and Blagojević, Duško and Spasojević, Ivan and Spasić, Mihajlo",
year = "2017",
abstract = "Pectin is the main soluble fiber in apples or citruses. It may be fermented by gut microbiota to metabolites showing local intestinal and systemic effects. A wide range of beneficial effects of dietary pectin includes impacts on the redox milieu and microbiota profile. We prepared pectin-derived oligosaccharides (apple (APDO) and citrus) and polygalacturonic acid-derived oligosaccharides, using alkaline hydrolysis by hydrogen peroxide, and analyzed them by Fourier Transform Infrared spectrometry. Furthermore, we analyzed the effects of pectin-derived oligosaccharides on hydroxyl radical (HO)-generating Fenton reaction using electron paramagnetic resonance spin-trapping spectroscopy, and the effects on the growth of Escherichia coli and Staphylococcus aureus in the presence of dietary-relevant HO-generating system (iron+ascorbate). The oligosaccharides react with HO radical to produce carbon dioxide radical anion (CO 2 - ). A comparative analysis showed that APDO has the most prominent bacteriostatic effect. This might be at least partially related to the higher capacity of APDO to produce CO 2 - , which specifically targets proteins and appears to have a longer lifetime and larger diffusion radius in biological systems compared to HO.",
journal = "Food Research International",
title = "Apple pectin-derived oligosaccharides produce carbon dioxide radical anion in Fenton reaction and prevent growth of Escherichia coli and Staphylococcus aureus",
doi = "10.1016/j.foodres.2017.08.040"
}
Martinov, J., Krstić, M., Spasić, S., Miletić, S., Stefanović-Kojić, J., Nikolić-Kokić, A., Blagojević, D., Spasojević, I.,& Spasić, M.. (2017). Apple pectin-derived oligosaccharides produce carbon dioxide radical anion in Fenton reaction and prevent growth of Escherichia coli and Staphylococcus aureus. in Food Research International.
https://doi.org/10.1016/j.foodres.2017.08.040
Martinov J, Krstić M, Spasić S, Miletić S, Stefanović-Kojić J, Nikolić-Kokić A, Blagojević D, Spasojević I, Spasić M. Apple pectin-derived oligosaccharides produce carbon dioxide radical anion in Fenton reaction and prevent growth of Escherichia coli and Staphylococcus aureus. in Food Research International. 2017;.
doi:10.1016/j.foodres.2017.08.040 .
Martinov, Jelena, Krstić, Miodrag, Spasić, Snežana, Miletić, Srdjan, Stefanović-Kojić, Jovana, Nikolić-Kokić, Aleksandra, Blagojević, Duško, Spasojević, Ivan, Spasić, Mihajlo, "Apple pectin-derived oligosaccharides produce carbon dioxide radical anion in Fenton reaction and prevent growth of Escherichia coli and Staphylococcus aureus" in Food Research International (2017),
https://doi.org/10.1016/j.foodres.2017.08.040 . .
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