@conference{
editor = "Đurić, Dragan, Jakovljević, Vladimir",
author = "Balind, Snežana and Manojlović-Stojanoski, Milica and Milošević, Verica and Todorović, Dajana and Nikolić, Ljiljana and Petković, Branka",
year = "2014",
abstract = "Presence of an alternating magnetic field of extremely low frequency (ELF-MF, <300
Hz) is correlated with technological development in a modem world. ELF-MF shows
its influence on different cell types and organs and leads to changes in ion cuffents, neurotransmission
and behavior. Modern medicine uses some positive aspects of ELF-MF
action for treating some conditions like anxiety, depression, and schizophrenia. Bearing
in mind that hlpothalamo-pituitary- adrenal (HPA) axis is a system responsible for maintaining
homeostasis in organisms, the aim of the present study was to determine does
extremely low frequency magnetic field (50 Hz, 0.5 mT) affect pituitary adrenocorticotroph
(ACTH) cells in adult animals. The following experiments were perfonned: 3
month old rats were shofi-term exposed to ELF-MF either for I or 7 days, while longterm
exposure to ELF-MF was conducted on rats from their conception to 3 months of
age. Stereological analysis was performed on immunolabeled pituitary ACTH cells.
Specifically, we measured total number and volume ofACTH cells, the volume of theiL
nuclei and pituitary volume. Obtained data showed that ELF-MF exposure for 1 da1'
significantly decreased total number and volume of ACTH cells, the volume of their
nuclei, as well as pituitary volume. Furlhermore, 7 days ELF-MF exposure significantir
reduced only the ACTH cells volume. Life-long exposure to ELF-MF decreased thc
volume of ACTH cells as well as the pituitary volume. Based on these results we can
conclude that the applied ELF-MF has a strong influence on the pituitary ACTH cells
tnotphometrical parameters and could be characterized as a stressogenic factor.",
publisher = "Belgrade: Serbian Physiological Society",
journal = "3rd Congress of Physiological Sciences of Serbia With International Participation",
title = "Exposure to alternating magnetic field (50 Hz, 0.5 mT) affects rat pituitary ACTH cells",
pages = "178",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_4026"
}