TY  - JOUR
AU  - Keković, Goran
AU  - Sekulić, S.
PY  - 2019
UR  - http://link.springer.com/10.1007/s11062-019-09783-y
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3368
AB  - We investigated change point detection (CPD) in time series composed of harmonic functions driven by Gaussian noise (in EEGs, in particular) and proposed a method of moving average filters in conjunction with wavelet transform. Numerical simulations showed that CPD runs over 90% within the frequency band <40 Hz. This means that detection of structural change points is almost guaranteed in the respective cases. The mean absolute error (MAE) as a measure of performance of the method was below 5%. The method is rather robust against noise. It has been demonstrated that CPD is possible at the noise amplitude exceeding 25% of the amplitude of harmonic functions. In application of the proposed method on the signals, CPD appeared in 74% of the analyzed EEGs.
T2  - Neurophysiology
T2  - Neurophysiology
T1  - Detection of Change Points in Time Series with Moving Average Filters and Wavelet Transform: Application to EEG Signals
IS  - 1
VL  - 51
DO  - 10.1007/s11062-019-09783-y
SP  - 2
EP  - 8
ER  - 

@article{
author = "Keković, Goran and Sekulić, S.",
year = "2019",
abstract = "We investigated change point detection (CPD) in time series composed of harmonic functions driven by Gaussian noise (in EEGs, in particular) and proposed a method of moving average filters in conjunction with wavelet transform. Numerical simulations showed that CPD runs over 90% within the frequency band <40 Hz. This means that detection of structural change points is almost guaranteed in the respective cases. The mean absolute error (MAE) as a measure of performance of the method was below 5%. The method is rather robust against noise. It has been demonstrated that CPD is possible at the noise amplitude exceeding 25% of the amplitude of harmonic functions. In application of the proposed method on the signals, CPD appeared in 74% of the analyzed EEGs.",
journal = "Neurophysiology, Neurophysiology",
title = "Detection of Change Points in Time Series with Moving Average Filters and Wavelet Transform: Application to EEG Signals",
number = "1",
volume = "51",
doi = "10.1007/s11062-019-09783-y",
pages = "2-8"
}

Keković, G.,& Sekulić, S.. (2019). Detection of Change Points in Time Series with Moving Average Filters and Wavelet Transform: Application to EEG Signals. in Neurophysiology, 51(1), 2-8.
https://doi.org/10.1007/s11062-019-09783-y

Keković G, Sekulić S. Detection of Change Points in Time Series with Moving Average Filters and Wavelet Transform: Application to EEG Signals. in Neurophysiology. 2019;51(1):2-8.
doi:10.1007/s11062-019-09783-y .

Keković, Goran, Sekulić, S., "Detection of Change Points in Time Series with Moving Average Filters and Wavelet Transform: Application to EEG Signals" in Neurophysiology, 51, no. 1 (2019):2-8,
https://doi.org/10.1007/s11062-019-09783-y . .

TY  - JOUR
AU  - Sekulić, S.
AU  - Keković, G.
AU  - Filipović, Danka
AU  - Drapšin, M.
AU  - Podgorac, Jelena
AU  - Martać, Ljiljana
AU  - Novakov-Mikić, Aleksandra
PY  - 2013
PY  - 2013
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/350
AB  - The aim of this work was to determine the changes in the duration of spontaneous movements in the guinea pig fetus after the appearance of its first movements. Every day from the 25th to the 35th gestation day, one fetus from each of twenty pregnant animals was examined by ultrasound. Fetal movements were observed for 5 min. The episode with the longest period of movement was taken into consideration and was recorded as: <1 s, 1-3 s, and >3 s. Days 25 and 26 were characterized by episodes lasting <1 s; days 29 to 31 were dominated by episodes lasting 1-3 s, and days 34 and 35 by episodes lasting >3 s (χ2 = 140.51 p <0.05). Tracking the dynamics of progressive increases in the longest episode of spontaneous movement could be a useful factor in estimating the maturity and condition of a fetus.
T2  - Archives of Biological Sciences
T1  - Monitoring the progressive increase of the longest episode of spontaneous movements in Guinea pig fetus
IS  - 4
VL  - 65
SP  - 1459
EP  - 1462
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_350
ER  - 

@article{
author = "Sekulić, S. and Keković, G. and Filipović, Danka and Drapšin, M. and Podgorac, Jelena and Martać, Ljiljana and Novakov-Mikić, Aleksandra",
year = "2013, 2013",
abstract = "The aim of this work was to determine the changes in the duration of spontaneous movements in the guinea pig fetus after the appearance of its first movements. Every day from the 25th to the 35th gestation day, one fetus from each of twenty pregnant animals was examined by ultrasound. Fetal movements were observed for 5 min. The episode with the longest period of movement was taken into consideration and was recorded as: <1 s, 1-3 s, and >3 s. Days 25 and 26 were characterized by episodes lasting <1 s; days 29 to 31 were dominated by episodes lasting 1-3 s, and days 34 and 35 by episodes lasting >3 s (χ2 = 140.51 p <0.05). Tracking the dynamics of progressive increases in the longest episode of spontaneous movement could be a useful factor in estimating the maturity and condition of a fetus.",
journal = "Archives of Biological Sciences",
title = "Monitoring the progressive increase of the longest episode of spontaneous movements in Guinea pig fetus",
number = "4",
volume = "65",
pages = "1459-1462",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_350"
}

Sekulić, S., Keković, G., Filipović, D., Drapšin, M., Podgorac, J., Martać, L.,& Novakov-Mikić, A.. (2013). Monitoring the progressive increase of the longest episode of spontaneous movements in Guinea pig fetus. in Archives of Biological Sciences, 65(4), 1459-1462.
https://hdl.handle.net/21.15107/rcub_ibiss_350

Sekulić S, Keković G, Filipović D, Drapšin M, Podgorac J, Martać L, Novakov-Mikić A. Monitoring the progressive increase of the longest episode of spontaneous movements in Guinea pig fetus. in Archives of Biological Sciences. 2013;65(4):1459-1462.
https://hdl.handle.net/21.15107/rcub_ibiss_350 .

Sekulić, S., Keković, G., Filipović, Danka, Drapšin, M., Podgorac, Jelena, Martać, Ljiljana, Novakov-Mikić, Aleksandra, "Monitoring the progressive increase of the longest episode of spontaneous movements in Guinea pig fetus" in Archives of Biological Sciences, 65, no. 4 (2013):1459-1462,
https://hdl.handle.net/21.15107/rcub_ibiss_350 .

TY  - JOUR
AU  - Martać, Ljiljana
AU  - Podgorac, Jelena
AU  - Sekulić, S.
PY  - 2010
PY  - 2010
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/261
AB  - Our previous investigations on an animal model of neurotoxicity show that increased power in the delta range is connected with the neurotoxic effect of aluminum exposure. In this study we used several aluminum-treated animals as a reliable model for the evaluation of the neurotoxic effects of aluminum on neurons, and compared it with a control group. We conclude that spectral analysis and the ratio between the delta and theta ranges might be reliable for a qualitative description of the neurotoxic effect of aluminum, and that the t test might be used to evaluate the change in brain activity between the treated and control groups of animals. The animal model under anesthesia was used to describe the state of brain activity with neurotoxicity with suppressed functional connectivity in the brain structure. We also performed fractal analysis to quantitatively describe neurotoxic effect in different pathophysiological states of animals treated with different doses of aluminum. A decrease in the fractal dimension is an indicator of neurodegeneration in the state of stress. This animal model is suitable for evaluation of the neurodegenerative processes in Alzheimer's dementia and Parkinson's disease.
AB  - Prethodna istraživanja na animalnom modelu neurotoksičnosti aluminijuma pokazuju da povećanje spektralne snage u delta opsegu je indikator neurotoksičnosti. U ovoj studiji smo koristili nekoliko životinja koje su pogodne za procenu neurotoksičnog efekta aluminijuma u poređenju sa kontrolom. Za kvalitativni opis neurotoksičnosti koristili smo odnos delta i teta opsega i t test za opis promene između tretiranih i kontrolnih pacova. Korišćen je animalni model u uslovima anestezije je opis moždane aktivnosti sa suprimiranim funkcionalnim vezama između moždanih struktura. Koristili smo i fraktalnu dimenziju za kvantitativni opis neurotoksičnog efekta u različitim patofiziološkim stanjima. Smanjenje fraktalne dimenzije je izraz neurodegeneracije u uslovima stresa. Ovaj model je komparabilan sa neurodegenerativnim i neurotransmiterskim promenama u Alchejmerovoj bolesti i Parkinsonovoj bolesti.
T2  - Archives of Biological Sciences
T1  - Procena neurotoksičnog efekta aluminijuma u animalnom modelu Wistar pacova
T1  - Evaluation of the neurotoxical effect of aluminum on the Wistar rat
IS  - 3
VL  - 62
SP  - 585
EP  - 588
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_261
ER  - 

@article{
author = "Martać, Ljiljana and Podgorac, Jelena and Sekulić, S.",
year = "2010, 2010",
abstract = "Our previous investigations on an animal model of neurotoxicity show that increased power in the delta range is connected with the neurotoxic effect of aluminum exposure. In this study we used several aluminum-treated animals as a reliable model for the evaluation of the neurotoxic effects of aluminum on neurons, and compared it with a control group. We conclude that spectral analysis and the ratio between the delta and theta ranges might be reliable for a qualitative description of the neurotoxic effect of aluminum, and that the t test might be used to evaluate the change in brain activity between the treated and control groups of animals. The animal model under anesthesia was used to describe the state of brain activity with neurotoxicity with suppressed functional connectivity in the brain structure. We also performed fractal analysis to quantitatively describe neurotoxic effect in different pathophysiological states of animals treated with different doses of aluminum. A decrease in the fractal dimension is an indicator of neurodegeneration in the state of stress. This animal model is suitable for evaluation of the neurodegenerative processes in Alzheimer's dementia and Parkinson's disease., Prethodna istraživanja na animalnom modelu neurotoksičnosti aluminijuma pokazuju da povećanje spektralne snage u delta opsegu je indikator neurotoksičnosti. U ovoj studiji smo koristili nekoliko životinja koje su pogodne za procenu neurotoksičnog efekta aluminijuma u poređenju sa kontrolom. Za kvalitativni opis neurotoksičnosti koristili smo odnos delta i teta opsega i t test za opis promene između tretiranih i kontrolnih pacova. Korišćen je animalni model u uslovima anestezije je opis moždane aktivnosti sa suprimiranim funkcionalnim vezama između moždanih struktura. Koristili smo i fraktalnu dimenziju za kvantitativni opis neurotoksičnog efekta u različitim patofiziološkim stanjima. Smanjenje fraktalne dimenzije je izraz neurodegeneracije u uslovima stresa. Ovaj model je komparabilan sa neurodegenerativnim i neurotransmiterskim promenama u Alchejmerovoj bolesti i Parkinsonovoj bolesti.",
journal = "Archives of Biological Sciences",
title = "Procena neurotoksičnog efekta aluminijuma u animalnom modelu Wistar pacova, Evaluation of the neurotoxical effect of aluminum on the Wistar rat",
number = "3",
volume = "62",
pages = "585-588",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_261"
}

Martać, L., Podgorac, J.,& Sekulić, S.. (2010). Procena neurotoksičnog efekta aluminijuma u animalnom modelu Wistar pacova. in Archives of Biological Sciences, 62(3), 585-588.
https://hdl.handle.net/21.15107/rcub_ibiss_261

Martać L, Podgorac J, Sekulić S. Procena neurotoksičnog efekta aluminijuma u animalnom modelu Wistar pacova. in Archives of Biological Sciences. 2010;62(3):585-588.
https://hdl.handle.net/21.15107/rcub_ibiss_261 .

Martać, Ljiljana, Podgorac, Jelena, Sekulić, S., "Procena neurotoksičnog efekta aluminijuma u animalnom modelu Wistar pacova" in Archives of Biological Sciences, 62, no. 3 (2010):585-588,
https://hdl.handle.net/21.15107/rcub_ibiss_261 .

TY  - JOUR
AU  - Martać, Ljiljana
AU  - Stojadinović, Gordana
AU  - Keković, G.
AU  - Podgorac, Jelena
AU  - Ćulić, Milka
AU  - Sekulić, S.
AU  - Lalošević, D.
AU  - Čapo, I.
PY  - 2010
PY  - 2010
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/243
AB  - Exposure to aluminium during gestation causes changes in mammalian brain development and behavior. Our aim was to perform spectral analysis on electrocortical activity of Sprague Dawley male pups (30±3 days of age) whose mothers were treated with aluminium during gestation and lactation. There was a higher presence of power spectra in the delta range of parietal electrocortical activity, a lower presence in the theta range and increased values of the parameter DT as the ratio of delta to theta range in pups indirectly exposed to aluminium (whose mothers were drinking a 0.5% water solution of aluminium chloride during the gestation and lactation periods), compared to controls.
AB  - Izlaganje dejstvu aluminijuma tokom gestacije i laktacije može dovesti do promena u razviću mozga i ponašanja kod sisara. Naš cilj je bio da se uradi spektralna analiza elektrokortikalne aktivnosti mladih Sprague Dawley pacova muškog pola (starosti 30±3 dana) čije su majke bile tretirane aluminijumom tokom gestacije i laktacije. U poređenju sa kontrolom, kod mladih pacova koji su bili indirektno trovani aluminijumom (čije su majke pile 0,5 % vodeni rastvor AlCl3 tokom gestacionog i laktacionog perioda) postoji veća zastupljenost delta ritma aktivnosti kore velikog mozga, manje prisustvo teta ritma, kao i porast parametra DT kao odnos između delta i teta opsega.
T2  - Archives of Biological Sciences
T1  - Spektralne promene moždane aktivnosti kod mladunaca pacova izloženih dejstvu aluminijuma tokom gestacije i laktacije
T1  - Spectral changes of brain activity in rat offspring exposed to aluminium during gestation and lactation
IS  - 1
VL  - 62
SP  - 9
EP  - 13
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_243
ER  - 

@article{
author = "Martać, Ljiljana and Stojadinović, Gordana and Keković, G. and Podgorac, Jelena and Ćulić, Milka and Sekulić, S. and Lalošević, D. and Čapo, I.",
year = "2010, 2010",
abstract = "Exposure to aluminium during gestation causes changes in mammalian brain development and behavior. Our aim was to perform spectral analysis on electrocortical activity of Sprague Dawley male pups (30±3 days of age) whose mothers were treated with aluminium during gestation and lactation. There was a higher presence of power spectra in the delta range of parietal electrocortical activity, a lower presence in the theta range and increased values of the parameter DT as the ratio of delta to theta range in pups indirectly exposed to aluminium (whose mothers were drinking a 0.5% water solution of aluminium chloride during the gestation and lactation periods), compared to controls., Izlaganje dejstvu aluminijuma tokom gestacije i laktacije može dovesti do promena u razviću mozga i ponašanja kod sisara. Naš cilj je bio da se uradi spektralna analiza elektrokortikalne aktivnosti mladih Sprague Dawley pacova muškog pola (starosti 30±3 dana) čije su majke bile tretirane aluminijumom tokom gestacije i laktacije. U poređenju sa kontrolom, kod mladih pacova koji su bili indirektno trovani aluminijumom (čije su majke pile 0,5 % vodeni rastvor AlCl3 tokom gestacionog i laktacionog perioda) postoji veća zastupljenost delta ritma aktivnosti kore velikog mozga, manje prisustvo teta ritma, kao i porast parametra DT kao odnos između delta i teta opsega.",
journal = "Archives of Biological Sciences",
title = "Spektralne promene moždane aktivnosti kod mladunaca pacova izloženih dejstvu aluminijuma tokom gestacije i laktacije, Spectral changes of brain activity in rat offspring exposed to aluminium during gestation and lactation",
number = "1",
volume = "62",
pages = "9-13",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_243"
}

Martać, L., Stojadinović, G., Keković, G., Podgorac, J., Ćulić, M., Sekulić, S., Lalošević, D.,& Čapo, I.. (2010). Spektralne promene moždane aktivnosti kod mladunaca pacova izloženih dejstvu aluminijuma tokom gestacije i laktacije. in Archives of Biological Sciences, 62(1), 9-13.
https://hdl.handle.net/21.15107/rcub_ibiss_243

Martać L, Stojadinović G, Keković G, Podgorac J, Ćulić M, Sekulić S, Lalošević D, Čapo I. Spektralne promene moždane aktivnosti kod mladunaca pacova izloženih dejstvu aluminijuma tokom gestacije i laktacije. in Archives of Biological Sciences. 2010;62(1):9-13.
https://hdl.handle.net/21.15107/rcub_ibiss_243 .

Martać, Ljiljana, Stojadinović, Gordana, Keković, G., Podgorac, Jelena, Ćulić, Milka, Sekulić, S., Lalošević, D., Čapo, I., "Spektralne promene moždane aktivnosti kod mladunaca pacova izloženih dejstvu aluminijuma tokom gestacije i laktacije" in Archives of Biological Sciences, 62, no. 1 (2010):9-13,
https://hdl.handle.net/21.15107/rcub_ibiss_243 .