TY  - JOUR
AU  - Venturelli, Leonardo
AU  - Kohler, Anne-Céline
AU  - Stupar, Petar
AU  - Villalba, Maria I.
AU  - Kalauzi, Aleksandar
AU  - Radotić, Ksenija
AU  - Bertacchi, Massimiliano
AU  - Dinarelli, Simone
AU  - Girasole, Marco
AU  - Pešić, Milica
AU  - Banković, Jasna
AU  - Vela, Maria E.
AU  - Yantorno, Osvaldo
AU  - Willaert, Ronnie
AU  - Dietler, Giovanni
AU  - Longo, Giovanni
AU  - Kasas, Sandor
PY  - 2020
UR  - http://doi.wiley.com/10.1002/jmr.2849
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3641
AB  - The insurgence of newly arising, rapidly developing health threats, such as drug-resistant bacteria and cancers, is one of the most urgent public-health issues of modern times. This menace calls for the development of sensitive and reliable diagnostic tools to monitor the response of single cells to chemical or pharmaceutical stimuli. Recently, it has been demonstrated that all living organisms oscillate at a nanometric scale and that these oscillations stop as soon as the organisms die. These nanometric scale oscillations can be detected by depositing living cells onto a micro-fabricated cantilever and by monitoring its displacements with an atomic force microscope-based electronics. Such devices, named nanomotion sensors, have been employed to determine the resistance profiles of life-threatening bacteria within minutes, to evaluate, among others, the effect of chemicals on yeast, neurons, and cancer cells. The data obtained so far demonstrate the advantages of nanomotion sensing devices in rapidly characterizing microorganism susceptibility to pharmaceutical agents. Here, we review the key aspects of this technique, presenting its major applications. and detailing its working protocols.
T2  - Journal of Molecular Recognition
T1  - A perspective view on the nanomotion detection of living organisms and its features
DO  - 10.1002/jmr.2849
SP  - e2849
ER  - 

@article{
author = "Venturelli, Leonardo and Kohler, Anne-Céline and Stupar, Petar and Villalba, Maria I. and Kalauzi, Aleksandar and Radotić, Ksenija and Bertacchi, Massimiliano and Dinarelli, Simone and Girasole, Marco and Pešić, Milica and Banković, Jasna and Vela, Maria E. and Yantorno, Osvaldo and Willaert, Ronnie and Dietler, Giovanni and Longo, Giovanni and Kasas, Sandor",
year = "2020",
abstract = "The insurgence of newly arising, rapidly developing health threats, such as drug-resistant bacteria and cancers, is one of the most urgent public-health issues of modern times. This menace calls for the development of sensitive and reliable diagnostic tools to monitor the response of single cells to chemical or pharmaceutical stimuli. Recently, it has been demonstrated that all living organisms oscillate at a nanometric scale and that these oscillations stop as soon as the organisms die. These nanometric scale oscillations can be detected by depositing living cells onto a micro-fabricated cantilever and by monitoring its displacements with an atomic force microscope-based electronics. Such devices, named nanomotion sensors, have been employed to determine the resistance profiles of life-threatening bacteria within minutes, to evaluate, among others, the effect of chemicals on yeast, neurons, and cancer cells. The data obtained so far demonstrate the advantages of nanomotion sensing devices in rapidly characterizing microorganism susceptibility to pharmaceutical agents. Here, we review the key aspects of this technique, presenting its major applications. and detailing its working protocols.",
journal = "Journal of Molecular Recognition",
title = "A perspective view on the nanomotion detection of living organisms and its features",
doi = "10.1002/jmr.2849",
pages = "e2849"
}

Venturelli, L., Kohler, A., Stupar, P., Villalba, M. I., Kalauzi, A., Radotić, K., Bertacchi, M., Dinarelli, S., Girasole, M., Pešić, M., Banković, J., Vela, M. E., Yantorno, O., Willaert, R., Dietler, G., Longo, G.,& Kasas, S.. (2020). A perspective view on the nanomotion detection of living organisms and its features. in Journal of Molecular Recognition, e2849.
https://doi.org/10.1002/jmr.2849

Venturelli L, Kohler A, Stupar P, Villalba MI, Kalauzi A, Radotić K, Bertacchi M, Dinarelli S, Girasole M, Pešić M, Banković J, Vela ME, Yantorno O, Willaert R, Dietler G, Longo G, Kasas S. A perspective view on the nanomotion detection of living organisms and its features. in Journal of Molecular Recognition. 2020;:e2849.
doi:10.1002/jmr.2849 .

Venturelli, Leonardo, Kohler, Anne-Céline, Stupar, Petar, Villalba, Maria I., Kalauzi, Aleksandar, Radotić, Ksenija, Bertacchi, Massimiliano, Dinarelli, Simone, Girasole, Marco, Pešić, Milica, Banković, Jasna, Vela, Maria E., Yantorno, Osvaldo, Willaert, Ronnie, Dietler, Giovanni, Longo, Giovanni, Kasas, Sandor, "A perspective view on the nanomotion detection of living organisms and its features" in Journal of Molecular Recognition (2020):e2849,
https://doi.org/10.1002/jmr.2849 . .

TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Spasojević, Dragica
AU  - Orlovska, Irina
AU  - Kozyrovska, Natalia
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Dmitrović, Svetlana
AU  - Matović, Branko
AU  - Tasić, Nikola
AU  - Maksimović, Vuk
AU  - Sosnin, Mikhail
AU  - Radotić, Ksenija
PY  - 2018
UR  - https://doi.org/10.1016/j.ijbiomac.2018.06.067
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3102
AB  - Lignins and lignin-derived compounds are known to have antibacterial properties. The wound healing agents in the form of dressings produce faster skin repair and decrease pain in patients. In order to create an efficient antimicrobial agent in the form of dressing in the treatment of chronic wounds, a composite hydrogel of bacterial cellulose (BC) and dehydrogenative polymer of coniferyl alcohol (DHP), BC-DHP, was designed. Novel composite showed inhibitory or bactericidal effects against selected pathogenic bacteria, including clinically isolated ones. The highest release rate of DHP was in the first hour, while after 24 h there was still slow release of small amounts of DHP from BC-DHP during 72 h monitoring. High-performance liquid chromatography coupled with mass-spectrometry showed that BC-DHP releases DHP oligomers, which are proposed to be antimicrobially active DHP fractions. Scanning electron microscopy and atomic force microscopy micrographs proved a dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number and size in the cellulose membrane. The Fourier-transform infrared absorption spectra of the BC-DHP showed that DHP was partly bound to the BC matrix. The swelling and crystallinity degree were dose-dependent. All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.
T2  - International Journal of Biological Macromolecules
T1  - Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing
DO  - 10.1016/j.ijbiomac.2018.06.067
ER  - 

@article{
author = "Zmejkoski, Danica and Spasojević, Dragica and Orlovska, Irina and Kozyrovska, Natalia and Soković, Marina and Glamočlija, Jasmina and Dmitrović, Svetlana and Matović, Branko and Tasić, Nikola and Maksimović, Vuk and Sosnin, Mikhail and Radotić, Ksenija",
year = "2018",
abstract = "Lignins and lignin-derived compounds are known to have antibacterial properties. The wound healing agents in the form of dressings produce faster skin repair and decrease pain in patients. In order to create an efficient antimicrobial agent in the form of dressing in the treatment of chronic wounds, a composite hydrogel of bacterial cellulose (BC) and dehydrogenative polymer of coniferyl alcohol (DHP), BC-DHP, was designed. Novel composite showed inhibitory or bactericidal effects against selected pathogenic bacteria, including clinically isolated ones. The highest release rate of DHP was in the first hour, while after 24 h there was still slow release of small amounts of DHP from BC-DHP during 72 h monitoring. High-performance liquid chromatography coupled with mass-spectrometry showed that BC-DHP releases DHP oligomers, which are proposed to be antimicrobially active DHP fractions. Scanning electron microscopy and atomic force microscopy micrographs proved a dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number and size in the cellulose membrane. The Fourier-transform infrared absorption spectra of the BC-DHP showed that DHP was partly bound to the BC matrix. The swelling and crystallinity degree were dose-dependent. All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.",
journal = "International Journal of Biological Macromolecules",
title = "Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing",
doi = "10.1016/j.ijbiomac.2018.06.067"
}

Zmejkoski, D., Spasojević, D., Orlovska, I., Kozyrovska, N., Soković, M., Glamočlija, J., Dmitrović, S., Matović, B., Tasić, N., Maksimović, V., Sosnin, M.,& Radotić, K.. (2018). Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing. in International Journal of Biological Macromolecules.
https://doi.org/10.1016/j.ijbiomac.2018.06.067

Zmejkoski D, Spasojević D, Orlovska I, Kozyrovska N, Soković M, Glamočlija J, Dmitrović S, Matović B, Tasić N, Maksimović V, Sosnin M, Radotić K. Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing. in International Journal of Biological Macromolecules. 2018;.
doi:10.1016/j.ijbiomac.2018.06.067 .

Zmejkoski, Danica, Spasojević, Dragica, Orlovska, Irina, Kozyrovska, Natalia, Soković, Marina, Glamočlija, Jasmina, Dmitrović, Svetlana, Matović, Branko, Tasić, Nikola, Maksimović, Vuk, Sosnin, Mikhail, Radotić, Ksenija, "Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing" in International Journal of Biological Macromolecules (2018),
https://doi.org/10.1016/j.ijbiomac.2018.06.067 . .

TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Spasojević, Dragica
AU  - Orlovska, Irina
AU  - Kozyrovska, Natalia
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Dmitrović, Svetlana
AU  - Matović, Branko
AU  - Tasić, Nikola
AU  - Maksimović, Vuk
AU  - Sosnin, Mikhail
AU  - Radotić, Ksenija
PY  - 2018
UR  - https://www.sciencedirect.com/science/article/pii/S0141813018320919?via%3Dihub
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3101
AB  - Lignins and lignin-derived compounds are known to have antibacterial properties. The wound healing agents in the form of dressings produce faster skin repair and decrease pain in patients. In order to create an efficient antimicrobial agent in the form of dressing in the treatment of chronic wounds, a composite hydrogel of bacterial cellulose (BC) and dehydrogenative polymer of coniferyl alcohol (DHP), BC-DHP, was designed. Novel composite showed inhibitory or bactericidal effects against selected pathogenic bacteria, including clinically isolated ones. The highest release rate of DHP was in the first hour, while after 24 h there was still slow release of small amounts of DHP from BC-DHP during 72 h monitoring. High-performance liquid chromatography coupled with mass-spectrometry showed that BC-DHP releases DHP oligomers, which are proposed to be antimicrobially active DHP fractions. Scanning electron microscopy and atomic force microscopy micrographs proved a dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number and size in the cellulose membrane. The Fourier-transform infrared absorption spectra of the BC-DHP showed that DHP was partly bound to the BC matrix. The swelling and crystallinity degree were dose-dependent. All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.
T2  - International Journal of Biological Macromolecules
T1  - Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing.
IS  - Pt A
VL  - 118
DO  - 10.1016/j.ijbiomac.2018.06.067
SP  - 494
EP  - 503
ER  - 

@article{
author = "Zmejkoski, Danica and Spasojević, Dragica and Orlovska, Irina and Kozyrovska, Natalia and Soković, Marina and Glamočlija, Jasmina and Dmitrović, Svetlana and Matović, Branko and Tasić, Nikola and Maksimović, Vuk and Sosnin, Mikhail and Radotić, Ksenija",
year = "2018",
abstract = "Lignins and lignin-derived compounds are known to have antibacterial properties. The wound healing agents in the form of dressings produce faster skin repair and decrease pain in patients. In order to create an efficient antimicrobial agent in the form of dressing in the treatment of chronic wounds, a composite hydrogel of bacterial cellulose (BC) and dehydrogenative polymer of coniferyl alcohol (DHP), BC-DHP, was designed. Novel composite showed inhibitory or bactericidal effects against selected pathogenic bacteria, including clinically isolated ones. The highest release rate of DHP was in the first hour, while after 24 h there was still slow release of small amounts of DHP from BC-DHP during 72 h monitoring. High-performance liquid chromatography coupled with mass-spectrometry showed that BC-DHP releases DHP oligomers, which are proposed to be antimicrobially active DHP fractions. Scanning electron microscopy and atomic force microscopy micrographs proved a dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number and size in the cellulose membrane. The Fourier-transform infrared absorption spectra of the BC-DHP showed that DHP was partly bound to the BC matrix. The swelling and crystallinity degree were dose-dependent. All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.",
journal = "International Journal of Biological Macromolecules",
title = "Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing.",
number = "Pt A",
volume = "118",
doi = "10.1016/j.ijbiomac.2018.06.067",
pages = "494-503"
}

Zmejkoski, D., Spasojević, D., Orlovska, I., Kozyrovska, N., Soković, M., Glamočlija, J., Dmitrović, S., Matović, B., Tasić, N., Maksimović, V., Sosnin, M.,& Radotić, K.. (2018). Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing.. in International Journal of Biological Macromolecules, 118(Pt A), 494-503.
https://doi.org/10.1016/j.ijbiomac.2018.06.067

Zmejkoski D, Spasojević D, Orlovska I, Kozyrovska N, Soković M, Glamočlija J, Dmitrović S, Matović B, Tasić N, Maksimović V, Sosnin M, Radotić K. Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing.. in International Journal of Biological Macromolecules. 2018;118(Pt A):494-503.
doi:10.1016/j.ijbiomac.2018.06.067 .

Zmejkoski, Danica, Spasojević, Dragica, Orlovska, Irina, Kozyrovska, Natalia, Soković, Marina, Glamočlija, Jasmina, Dmitrović, Svetlana, Matović, Branko, Tasić, Nikola, Maksimović, Vuk, Sosnin, Mikhail, Radotić, Ksenija, "Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing." in International Journal of Biological Macromolecules, 118, no. Pt A (2018):494-503,
https://doi.org/10.1016/j.ijbiomac.2018.06.067 . .

TY  - JOUR
AU  - Spasojević, Dragica
AU  - Zmejkoski, Danica
AU  - Glamočlija, Jasmina
AU  - Nikolić, Miloš
AU  - Soković, Marina
AU  - Milošević, Verica
AU  - Jarić, Ivana
AU  - Stojanović, Marijana
AU  - Marinković, Emilija
AU  - Barisani-Asenbauer, Talin
AU  - Prodanović, Radivoje
AU  - Jovanović, Miloš
AU  - Radotić, Ksenija
PY  - 2016
UR  - http://linkinghub.elsevier.com/retrieve/pii/S0924857916302679
UR  - https://www.scopus.com/record/display.uri?eid=2-s2.0-85000995852&origin=SingleRecordEmailAlert&dgcid=scalert_sc_search_email&txGid=5EA0B882AD39CF37A9F768C8B10917B5.wsnAw8kcdt7IPYLO0V48gA%3A1#
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2480
AB  - Nowadays bacterial resistance to known antibiotics is a serious health problem. In order to achieve more efficient treatment, lately there is an effort to find new substances, such as certain biomaterials, that are non-toxic to humans with antibiotic potential. Lignins and lignin-derived compounds have been proposed to be good candidates for use in medicine and health maintenance. In this study, the antibacterial activity of the lignin model polymer dehydrogenate polymer (DHP) in alginate hydrogel (Alg) was studied. The obtained results show that DHP−Alg has strong antimicrobial activity against several bacterial strains and biofilms and does not have a toxic effect on human epithelial cells. These results strongly suggest its application as a wound healing agent or as an adjunct substance for wound treatments.
T2  - International Journal of Antimicrobial Agents
T1  - Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment
IS  - 6
VL  - 48
DO  - 10.1016/j.ijantimicag.2016.08.014
SP  - 732
EP  - 735
ER  - 

@article{
author = "Spasojević, Dragica and Zmejkoski, Danica and Glamočlija, Jasmina and Nikolić, Miloš and Soković, Marina and Milošević, Verica and Jarić, Ivana and Stojanović, Marijana and Marinković, Emilija and Barisani-Asenbauer, Talin and Prodanović, Radivoje and Jovanović, Miloš and Radotić, Ksenija",
year = "2016",
abstract = "Nowadays bacterial resistance to known antibiotics is a serious health problem. In order to achieve more efficient treatment, lately there is an effort to find new substances, such as certain biomaterials, that are non-toxic to humans with antibiotic potential. Lignins and lignin-derived compounds have been proposed to be good candidates for use in medicine and health maintenance. In this study, the antibacterial activity of the lignin model polymer dehydrogenate polymer (DHP) in alginate hydrogel (Alg) was studied. The obtained results show that DHP−Alg has strong antimicrobial activity against several bacterial strains and biofilms and does not have a toxic effect on human epithelial cells. These results strongly suggest its application as a wound healing agent or as an adjunct substance for wound treatments.",
journal = "International Journal of Antimicrobial Agents",
title = "Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment",
number = "6",
volume = "48",
doi = "10.1016/j.ijantimicag.2016.08.014",
pages = "732-735"
}

Spasojević, D., Zmejkoski, D., Glamočlija, J., Nikolić, M., Soković, M., Milošević, V., Jarić, I., Stojanović, M., Marinković, E., Barisani-Asenbauer, T., Prodanović, R., Jovanović, M.,& Radotić, K.. (2016). Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment. in International Journal of Antimicrobial Agents, 48(6), 732-735.
https://doi.org/10.1016/j.ijantimicag.2016.08.014

Spasojević D, Zmejkoski D, Glamočlija J, Nikolić M, Soković M, Milošević V, Jarić I, Stojanović M, Marinković E, Barisani-Asenbauer T, Prodanović R, Jovanović M, Radotić K. Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment. in International Journal of Antimicrobial Agents. 2016;48(6):732-735.
doi:10.1016/j.ijantimicag.2016.08.014 .

Spasojević, Dragica, Zmejkoski, Danica, Glamočlija, Jasmina, Nikolić, Miloš, Soković, Marina, Milošević, Verica, Jarić, Ivana, Stojanović, Marijana, Marinković, Emilija, Barisani-Asenbauer, Talin, Prodanović, Radivoje, Jovanović, Miloš, Radotić, Ksenija, "Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment" in International Journal of Antimicrobial Agents, 48, no. 6 (2016):732-735,
https://doi.org/10.1016/j.ijantimicag.2016.08.014 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Stošić-Grujičić, Stanislava
AU  - Bogdanović, Gordana M
AU  - Hegedis, Aleksandar E
AU  - Karaman, Ivo M
AU  - Stojanović, Ivana D.
AU  - Nikolić, Ivana
AU  - Kojić, Vesna V
AU  - Horvatović, Mladen
AU  - Radotić, Ksenija
PY  - 2013
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1060
AB  - The immunomodulatory and anticarcinogenic activity of the freshwater bryozoan Hyalinella punctata methanolic extract (MEx) was evaluated in vitro on selected biosystems for the first time. Murine lymphocytes and macrophages were used for testing of MEx effects on cell proliferation and nitric oxide (NO) production, respectively, while human cancer cell lines were utilized for measuring its activity against cancer cells. The results suggest a strong and tissue-specific immunomodifying activity (IC50 values for inhibition of proliferation of lymph node and spleen-derived lymphocytes were 4.1 mu g/ml and 9.7 mu g/ml, respectively) and moderate anticancer activity of MEx (IC50 value for the MCF-7 cell line was 24.13 mu g/ml). Down-regulation of macrophage NO production was also obtained. The potential use of H. punctata-derived natural products for the treatment of human chronic inflammatory diseases and cancer is worthy of further investigation.
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - In Vitro Evaluation of the Immunomodulatory and Anticarcinogenic Activity of the Freshwater Bryozoan Hyalinella Punctata Methanolic Extract
IS  - 1
VL  - 8
SP  - 301
EP  - 195
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1060
ER  - 

@article{
author = "Pejin, Boris and Stošić-Grujičić, Stanislava and Bogdanović, Gordana M and Hegedis, Aleksandar E and Karaman, Ivo M and Stojanović, Ivana D. and Nikolić, Ivana and Kojić, Vesna V and Horvatović, Mladen and Radotić, Ksenija",
year = "2013",
abstract = "The immunomodulatory and anticarcinogenic activity of the freshwater bryozoan Hyalinella punctata methanolic extract (MEx) was evaluated in vitro on selected biosystems for the first time. Murine lymphocytes and macrophages were used for testing of MEx effects on cell proliferation and nitric oxide (NO) production, respectively, while human cancer cell lines were utilized for measuring its activity against cancer cells. The results suggest a strong and tissue-specific immunomodifying activity (IC50 values for inhibition of proliferation of lymph node and spleen-derived lymphocytes were 4.1 mu g/ml and 9.7 mu g/ml, respectively) and moderate anticancer activity of MEx (IC50 value for the MCF-7 cell line was 24.13 mu g/ml). Down-regulation of macrophage NO production was also obtained. The potential use of H. punctata-derived natural products for the treatment of human chronic inflammatory diseases and cancer is worthy of further investigation.",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "In Vitro Evaluation of the Immunomodulatory and Anticarcinogenic Activity of the Freshwater Bryozoan Hyalinella Punctata Methanolic Extract",
number = "1",
volume = "8",
pages = "301-195",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1060"
}

Pejin, B., Stošić-Grujičić, S., Bogdanović, G. M., Hegedis, A. E., Karaman, I. M., Stojanović, I. D., Nikolić, I., Kojić, V. V., Horvatović, M.,& Radotić, K.. (2013). In Vitro Evaluation of the Immunomodulatory and Anticarcinogenic Activity of the Freshwater Bryozoan Hyalinella Punctata Methanolic Extract. in Digest Journal of Nanomaterials and Biostructures, 8(1), 301-195.
https://hdl.handle.net/21.15107/rcub_ibiss_1060

Pejin B, Stošić-Grujičić S, Bogdanović GM, Hegedis AE, Karaman IM, Stojanović ID, Nikolić I, Kojić VV, Horvatović M, Radotić K. In Vitro Evaluation of the Immunomodulatory and Anticarcinogenic Activity of the Freshwater Bryozoan Hyalinella Punctata Methanolic Extract. in Digest Journal of Nanomaterials and Biostructures. 2013;8(1):301-195.
https://hdl.handle.net/21.15107/rcub_ibiss_1060 .

Pejin, Boris, Stošić-Grujičić, Stanislava, Bogdanović, Gordana M, Hegedis, Aleksandar E, Karaman, Ivo M, Stojanović, Ivana D., Nikolić, Ivana, Kojić, Vesna V, Horvatović, Mladen, Radotić, Ksenija, "In Vitro Evaluation of the Immunomodulatory and Anticarcinogenic Activity of the Freshwater Bryozoan Hyalinella Punctata Methanolic Extract" in Digest Journal of Nanomaterials and Biostructures, 8, no. 1 (2013):301-195,
https://hdl.handle.net/21.15107/rcub_ibiss_1060 .

TY  - JOUR
AU  - Pejin, Boris
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana
AU  - Radotić, Ksenija
AU  - Vajs, Vlatka E
AU  - Tesević, Vele V
AU  - Hegedis, Aleksandar E
AU  - Karaman, Ivo M
AU  - Horvatović, Mladen
AU  - Soković, Marina
PY  - 2012
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1164
AB  - The antimicrobial activity of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) was tested by microdilution method against eight bacteria and eight fungi for the first time. All five crude extracts (hexane, acetone, dimethyl sulfoxide, methanol and water) showed good antibacterial and antifungal potential in vitro wherein the acetone extract was the most active (MICs 0.50-7.00 mu g/ml and MBCs 2.50-10.00 mu g/ml).
PB  - Bucharest: Virtual Co Physics Srl
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)
IS  - 3
VL  - 7
EP  - 1026
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1565
ER  - 

@article{
author = "Pejin, Boris and Glamočlija, Jasmina and Ćirić, Ana and Radotić, Ksenija and Vajs, Vlatka E and Tesević, Vele V and Hegedis, Aleksandar E and Karaman, Ivo M and Horvatović, Mladen and Soković, Marina",
year = "2012",
abstract = "The antimicrobial activity of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) was tested by microdilution method against eight bacteria and eight fungi for the first time. All five crude extracts (hexane, acetone, dimethyl sulfoxide, methanol and water) showed good antibacterial and antifungal potential in vitro wherein the acetone extract was the most active (MICs 0.50-7.00 mu g/ml and MBCs 2.50-10.00 mu g/ml).",
publisher = "Bucharest: Virtual Co Physics Srl",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)",
number = "3",
volume = "7",
pages = "1026",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1565"
}

Pejin, B., Glamočlija, J., Ćirić, A., Radotić, K., Vajs, V. E., Tesević, V. V., Hegedis, A. E., Karaman, I. M., Horvatović, M.,& Soković, M.. (2012). Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850). in Digest Journal of Nanomaterials and Biostructures
Bucharest: Virtual Co Physics Srl., 7(3).
https://hdl.handle.net/21.15107/rcub_cherry_1565

Pejin B, Glamočlija J, Ćirić A, Radotić K, Vajs VE, Tesević VV, Hegedis AE, Karaman IM, Horvatović M, Soković M. Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850). in Digest Journal of Nanomaterials and Biostructures. 2012;7(3):null-1026.
https://hdl.handle.net/21.15107/rcub_cherry_1565 .

Pejin, Boris, Glamočlija, Jasmina, Ćirić, Ana, Radotić, Ksenija, Vajs, Vlatka E, Tesević, Vele V, Hegedis, Aleksandar E, Karaman, Ivo M, Horvatović, Mladen, Soković, Marina, "Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)" in Digest Journal of Nanomaterials and Biostructures, 7, no. 3 (2012),
https://hdl.handle.net/21.15107/rcub_cherry_1565 .

TY  - JOUR
AU  - Radotić, Ksenija
AU  - Dučić, Tanja M.
AU  - Prodanović, Radivoje M.
AU  - Vujčić, Zoran M.
AU  - Karadžić, Branko
AU  - Antić-Jovanović, Svetlana
PY  - 2003
PY  - 2003
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/27
AB  - We studied the soluble peroxidase and superoxid-dismutase activity peroxidase isoenzyme pattern and metal content in the needles of 2-year-old spruce grown on soils supplemented with cadmium and nickel concentrations from 3 to 30 mg kg -1 and 50 to 500 mg kg -1 respectively. The two metals were applied both separately and simultaneously. The kinetics of metal assimilation and total accumulated quantity depended on the type of treatment. Following metal exposure, an increase in peroxidase activity in the seedlings treated with Cd and Ni/Cd, and in superoxide-dismutase activity during Ni/Cd treatment was observed. A parallel change of peroxidase isoenzyme pattern occurred. There was a good correlation between accumulated metals in needles and enzyme activities. The effect of Cd on the measured parameters was shown to be stronger comparing to the effect of Ni. The results obtained show that peroxidase and superoxide-dismutase activity and peroxidase isoenzyme pattern could be used to evaluate the capacity of one part of the defense system in spruce seedlings to with-stand metal stress.
AB  - Proučavana je aktivnost slobodnih peroksidaza i superoksid-dismutaza izoenzimski profil peroksidaza i sadržaj metala u četinama dvogodišnjih smrča gajenih na zemljištu u koje su dodavani kadmijum i nikl u koncentracijama 3 do 30 mg kg -1 i 50 do 500 mg kg -1 respektivno. Metali su dodavani na dva načina: zasebno i istovremeno. Kinetika usvajanja metala i ukupna akumulirana količina zavisili su od vrste tretmana. U tretiranim izdancima došlo je do povećanja peroksidazne aktivnosti u slučaju tretmana kadmijumom i nikl/kadmijumom, kao i superoksid-dismutazne aktivnosti u toku tretmana nikl/kadmijumom, u odnosu na netretirane biljke. Istovremeno je došlo do promene izoenzimskog sastava peroksidaza. Koncentracija akumuliranih metala u četinama je bila u dobroj korelaciji sa enzimskim aktivnostima. Pokazano je da je uticaj kadmijuma na merene parametre jači u poređenju sa uticajem nikla. Dobijeni rezultati pokazuju da peroksidazna i superoksid-dismutazna aktivnost i izoenzimski profil peroksidaza mogu da se koriste za procenu kapaciteta jednog dela zaštitnog sistema u izdancima smrče u odnosu na stres izazvan metalima.
T2  - Jugoslovenska medicinska biohemija
T1  - Toksičnost nikla i kadmijuma u četinama smrče: uticaj zasebnih i kombinovanih tretmana na peroksidaznu i superoksid-dismutaznu aktivnost
T1  - Toxicity of nickel and cadmium in spruce seedlings: Effect of separated and combined treatments on peroxidase and superoxide-dismutase activity
IS  - 1
VL  - 22
SP  - 41
EP  - 52
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_27
ER  - 

@article{
author = "Radotić, Ksenija and Dučić, Tanja M. and Prodanović, Radivoje M. and Vujčić, Zoran M. and Karadžić, Branko and Antić-Jovanović, Svetlana",
year = "2003, 2003",
abstract = "We studied the soluble peroxidase and superoxid-dismutase activity peroxidase isoenzyme pattern and metal content in the needles of 2-year-old spruce grown on soils supplemented with cadmium and nickel concentrations from 3 to 30 mg kg -1 and 50 to 500 mg kg -1 respectively. The two metals were applied both separately and simultaneously. The kinetics of metal assimilation and total accumulated quantity depended on the type of treatment. Following metal exposure, an increase in peroxidase activity in the seedlings treated with Cd and Ni/Cd, and in superoxide-dismutase activity during Ni/Cd treatment was observed. A parallel change of peroxidase isoenzyme pattern occurred. There was a good correlation between accumulated metals in needles and enzyme activities. The effect of Cd on the measured parameters was shown to be stronger comparing to the effect of Ni. The results obtained show that peroxidase and superoxide-dismutase activity and peroxidase isoenzyme pattern could be used to evaluate the capacity of one part of the defense system in spruce seedlings to with-stand metal stress., Proučavana je aktivnost slobodnih peroksidaza i superoksid-dismutaza izoenzimski profil peroksidaza i sadržaj metala u četinama dvogodišnjih smrča gajenih na zemljištu u koje su dodavani kadmijum i nikl u koncentracijama 3 do 30 mg kg -1 i 50 do 500 mg kg -1 respektivno. Metali su dodavani na dva načina: zasebno i istovremeno. Kinetika usvajanja metala i ukupna akumulirana količina zavisili su od vrste tretmana. U tretiranim izdancima došlo je do povećanja peroksidazne aktivnosti u slučaju tretmana kadmijumom i nikl/kadmijumom, kao i superoksid-dismutazne aktivnosti u toku tretmana nikl/kadmijumom, u odnosu na netretirane biljke. Istovremeno je došlo do promene izoenzimskog sastava peroksidaza. Koncentracija akumuliranih metala u četinama je bila u dobroj korelaciji sa enzimskim aktivnostima. Pokazano je da je uticaj kadmijuma na merene parametre jači u poređenju sa uticajem nikla. Dobijeni rezultati pokazuju da peroksidazna i superoksid-dismutazna aktivnost i izoenzimski profil peroksidaza mogu da se koriste za procenu kapaciteta jednog dela zaštitnog sistema u izdancima smrče u odnosu na stres izazvan metalima.",
journal = "Jugoslovenska medicinska biohemija",
title = "Toksičnost nikla i kadmijuma u četinama smrče: uticaj zasebnih i kombinovanih tretmana na peroksidaznu i superoksid-dismutaznu aktivnost, Toxicity of nickel and cadmium in spruce seedlings: Effect of separated and combined treatments on peroxidase and superoxide-dismutase activity",
number = "1",
volume = "22",
pages = "41-52",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_27"
}

Radotić, K., Dučić, T. M., Prodanović, R. M., Vujčić, Z. M., Karadžić, B.,& Antić-Jovanović, S.. (2003). Toksičnost nikla i kadmijuma u četinama smrče: uticaj zasebnih i kombinovanih tretmana na peroksidaznu i superoksid-dismutaznu aktivnost. in Jugoslovenska medicinska biohemija, 22(1), 41-52.
https://hdl.handle.net/21.15107/rcub_ibiss_27

Radotić K, Dučić TM, Prodanović RM, Vujčić ZM, Karadžić B, Antić-Jovanović S. Toksičnost nikla i kadmijuma u četinama smrče: uticaj zasebnih i kombinovanih tretmana na peroksidaznu i superoksid-dismutaznu aktivnost. in Jugoslovenska medicinska biohemija. 2003;22(1):41-52.
https://hdl.handle.net/21.15107/rcub_ibiss_27 .

Radotić, Ksenija, Dučić, Tanja M., Prodanović, Radivoje M., Vujčić, Zoran M., Karadžić, Branko, Antić-Jovanović, Svetlana, "Toksičnost nikla i kadmijuma u četinama smrče: uticaj zasebnih i kombinovanih tretmana na peroksidaznu i superoksid-dismutaznu aktivnost" in Jugoslovenska medicinska biohemija, 22, no. 1 (2003):41-52,
https://hdl.handle.net/21.15107/rcub_ibiss_27 .