TY  - JOUR
AU  - Nikolić, Miloš
AU  - Glamočlija, Jasmina
AU  - Ferreira, Isabel C. F. R.
AU  - Calhelha, Ricardo C.
AU  - Fernandes, Angela
AU  - Markovic, Tatjana
AU  - Markovic, Dejan
AU  - Giweli, Abdulhamed
AU  - Soković, Marina
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2300
AB  - Aromatic plant species of genus Thymus are important medicinal plants,
   highly recommended due to a range of therapeutic properties of their
   essential oils, commonly known as thyme oil: antirheumatic, antiseptic,
   antispasmodic, antimicrobial, cardiac, carminative, diuretic and
   expectorant. The oil is also beneficial in boosting the immune system
   and helps to fight colds, flu, infectious diseases and chills. It is
   proved to be a urinary antiseptic, being very helpful for cystitis and
   urethritis. Scientific validation of traditional uses, and phytochemical
   and bioactivity evaluation of essential oils from Thymus serpyllum,
   Thymus algeriensis and Thymus vulgaris were performed.
   GC/MS analysis revealed thymol as a major component of T. algeriensis,
   T. vulgaris and T. serpyllum, with its contribution to the oil 56.0\%,
   48.9\% and 38.5\%, respectively. All three essential oils (EOs)
   exhibited a significant antimicrobial activity against all tested
   strains, the T. serpyllum oil being the most potent one (MIC 2.5-5 mu
   g/mL, MBC 5-10 mu g/mL; MIC 1-2 mu g/mL, MFC 2-4 mu g/mL). In addition,
   the T. serpyllum oil revealed the highest antioxidant activity in all
   conducted assays and it was the most effective one against all tested
   cell lines, presenting GI(50) values of 7.02-52.69 mu g/mL. Moreover,
   none of the EOs showed toxicity at tested concentrations (>400 mu g/mL)
   for porcine liver primary cell culture. In addition to their well-known
   traditional use in food and cosmetics, the great potential of tested
   Thymus essential oils for application in oral diseases and anticancer
   treatments, encourage further investigation. (C) 2013 Elsevier B.V. All
   rights reserved.
T2  - Industrial Crops and Products
T1  - Chemical composition, antimicrobial, antioxidant and antitumor activity
 of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus
 vulgaris L. essential oils
VL  - 52
DO  - 10.1016/j.indcrop.2013.10.006
SP  - 183
EP  - 190
ER  - 

@article{
author = "Nikolić, Miloš and Glamočlija, Jasmina and Ferreira, Isabel C. F. R. and Calhelha, Ricardo C. and Fernandes, Angela and Markovic, Tatjana and Markovic, Dejan and Giweli, Abdulhamed and Soković, Marina",
year = "2014",
abstract = "Aromatic plant species of genus Thymus are important medicinal plants,
   highly recommended due to a range of therapeutic properties of their
   essential oils, commonly known as thyme oil: antirheumatic, antiseptic,
   antispasmodic, antimicrobial, cardiac, carminative, diuretic and
   expectorant. The oil is also beneficial in boosting the immune system
   and helps to fight colds, flu, infectious diseases and chills. It is
   proved to be a urinary antiseptic, being very helpful for cystitis and
   urethritis. Scientific validation of traditional uses, and phytochemical
   and bioactivity evaluation of essential oils from Thymus serpyllum,
   Thymus algeriensis and Thymus vulgaris were performed.
   GC/MS analysis revealed thymol as a major component of T. algeriensis,
   T. vulgaris and T. serpyllum, with its contribution to the oil 56.0\%,
   48.9\% and 38.5\%, respectively. All three essential oils (EOs)
   exhibited a significant antimicrobial activity against all tested
   strains, the T. serpyllum oil being the most potent one (MIC 2.5-5 mu
   g/mL, MBC 5-10 mu g/mL; MIC 1-2 mu g/mL, MFC 2-4 mu g/mL). In addition,
   the T. serpyllum oil revealed the highest antioxidant activity in all
   conducted assays and it was the most effective one against all tested
   cell lines, presenting GI(50) values of 7.02-52.69 mu g/mL. Moreover,
   none of the EOs showed toxicity at tested concentrations (>400 mu g/mL)
   for porcine liver primary cell culture. In addition to their well-known
   traditional use in food and cosmetics, the great potential of tested
   Thymus essential oils for application in oral diseases and anticancer
   treatments, encourage further investigation. (C) 2013 Elsevier B.V. All
   rights reserved.",
journal = "Industrial Crops and Products",
title = "Chemical composition, antimicrobial, antioxidant and antitumor activity
 of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus
 vulgaris L. essential oils",
volume = "52",
doi = "10.1016/j.indcrop.2013.10.006",
pages = "183-190"
}

Nikolić, M., Glamočlija, J., Ferreira, I. C. F. R., Calhelha, R. C., Fernandes, A., Markovic, T., Markovic, D., Giweli, A.,& Soković, M.. (2014). Chemical composition, antimicrobial, antioxidant and antitumor activity
 of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus
 vulgaris L. essential oils. in Industrial Crops and Products, 52, 183-190.
https://doi.org/10.1016/j.indcrop.2013.10.006

Nikolić M, Glamočlija J, Ferreira ICFR, Calhelha RC, Fernandes A, Markovic T, Markovic D, Giweli A, Soković M. Chemical composition, antimicrobial, antioxidant and antitumor activity
 of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus
 vulgaris L. essential oils. in Industrial Crops and Products. 2014;52:183-190.
doi:10.1016/j.indcrop.2013.10.006 .

Nikolić, Miloš, Glamočlija, Jasmina, Ferreira, Isabel C. F. R., Calhelha, Ricardo C., Fernandes, Angela, Markovic, Tatjana, Markovic, Dejan, Giweli, Abdulhamed, Soković, Marina, "Chemical composition, antimicrobial, antioxidant and antitumor activity
 of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus
 vulgaris L. essential oils" in Industrial Crops and Products, 52 (2014):183-190,
https://doi.org/10.1016/j.indcrop.2013.10.006 . .