TY  - JOUR
AU  - Petrović-Kosanović, Dragana
AU  - Ajdžanović, Vladimir
AU  - Čakić-Milošević, Maja
AU  - Koko, Vesna
AU  - Milošević, Verica
PY  - 2013
PY  - 2013
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/346
AB  - Hyperthermia can cause significant structural and functional reorganization of tissues and organs. The prolifera- tive and apoptotic processes of rat adrenal cortex were analyzed by light and electron microscopy after an acute exposure to high ambient temperature. Animals were divided in two groups. The first group consisted of intact controls. The rats from the second group were exposed to a high ambient temperature of 38°C for 60 min. Mitotic chromosomes and the largest number of immunoreactive nuclei for the Ki-67 were observed in the zona reticularis (ZR) of the control animals. The relative number of mitoses after heat stress showed a significant decrease in the zona glomerulosa (ZG; 66.8%), zona fasciculata (ZF; 27.8%) and ZR (86.7%) (for all zones p<0.05), while in the whole adrenal cortex the after-treatment decrease was 61.9% (p<0.05) compared to the controls. Under heat stress numerous apoptotic nuclei were seen at the light and ultrastructural levels in all the zones of the adrenal cortex. Such dynamics of mitosis/apoptosis events seriously affect adrenal cortex morphology.
T2  - Archives of Biological Sciences
T1  - The effects of acute heat stress on proliferative and apoptotic processes in the rat adrenal cortex
IS  - 3
VL  - 65
SP  - 905
EP  - 909
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_346
ER  - 

@article{
author = "Petrović-Kosanović, Dragana and Ajdžanović, Vladimir and Čakić-Milošević, Maja and Koko, Vesna and Milošević, Verica",
year = "2013, 2013",
abstract = "Hyperthermia can cause significant structural and functional reorganization of tissues and organs. The prolifera- tive and apoptotic processes of rat adrenal cortex were analyzed by light and electron microscopy after an acute exposure to high ambient temperature. Animals were divided in two groups. The first group consisted of intact controls. The rats from the second group were exposed to a high ambient temperature of 38°C for 60 min. Mitotic chromosomes and the largest number of immunoreactive nuclei for the Ki-67 were observed in the zona reticularis (ZR) of the control animals. The relative number of mitoses after heat stress showed a significant decrease in the zona glomerulosa (ZG; 66.8%), zona fasciculata (ZF; 27.8%) and ZR (86.7%) (for all zones p<0.05), while in the whole adrenal cortex the after-treatment decrease was 61.9% (p<0.05) compared to the controls. Under heat stress numerous apoptotic nuclei were seen at the light and ultrastructural levels in all the zones of the adrenal cortex. Such dynamics of mitosis/apoptosis events seriously affect adrenal cortex morphology.",
journal = "Archives of Biological Sciences",
title = "The effects of acute heat stress on proliferative and apoptotic processes in the rat adrenal cortex",
number = "3",
volume = "65",
pages = "905-909",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_346"
}

Petrović-Kosanović, D., Ajdžanović, V., Čakić-Milošević, M., Koko, V.,& Milošević, V.. (2013). The effects of acute heat stress on proliferative and apoptotic processes in the rat adrenal cortex. in Archives of Biological Sciences, 65(3), 905-909.
https://hdl.handle.net/21.15107/rcub_ibiss_346

Petrović-Kosanović D, Ajdžanović V, Čakić-Milošević M, Koko V, Milošević V. The effects of acute heat stress on proliferative and apoptotic processes in the rat adrenal cortex. in Archives of Biological Sciences. 2013;65(3):905-909.
https://hdl.handle.net/21.15107/rcub_ibiss_346 .

Petrović-Kosanović, Dragana, Ajdžanović, Vladimir, Čakić-Milošević, Maja, Koko, Vesna, Milošević, Verica, "The effects of acute heat stress on proliferative and apoptotic processes in the rat adrenal cortex" in Archives of Biological Sciences, 65, no. 3 (2013):905-909,
https://hdl.handle.net/21.15107/rcub_ibiss_346 .

TY  - JOUR
AU  - Petrović-Kosanović, Dragana
AU  - Ukropina, Mirela
AU  - Čakić-Milošević, Maja
AU  - Budeč, Mirela
AU  - Milošević, Verica
AU  - Koko, Vesna
PY  - 2013
PY  - 2013
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/329
AB  - Immunohistochemistry revealed the presence of Vasoactive Intestinal Peptide (VIP), Neuropeptide Y (NPY), and the absence of Substance P (SP) immunoreactivity in the rat adrenal cortex. VIP- and NPY-immunoreactivity were detected in nerve fibers around the small blood vessels projecting into the capsule and cortical zones surrounding blood vessels and cortical cells. After acute heat stress, VIP- and NPY-immunoreactivities in the nerve fibers were reduced, probably as a result of the release of these peptides.
T2  - Archives of Biological Sciences
T1  - Immunohistochemical evidence for the presence of a Vasoactive Intestinal Peptide, Neuropeptide Y, and Substance P, in rat adrenal cortex after acute heat stress
IS  - 1
VL  - 65
SP  - 315
EP  - 320
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_329
ER  - 

@article{
author = "Petrović-Kosanović, Dragana and Ukropina, Mirela and Čakić-Milošević, Maja and Budeč, Mirela and Milošević, Verica and Koko, Vesna",
year = "2013, 2013",
abstract = "Immunohistochemistry revealed the presence of Vasoactive Intestinal Peptide (VIP), Neuropeptide Y (NPY), and the absence of Substance P (SP) immunoreactivity in the rat adrenal cortex. VIP- and NPY-immunoreactivity were detected in nerve fibers around the small blood vessels projecting into the capsule and cortical zones surrounding blood vessels and cortical cells. After acute heat stress, VIP- and NPY-immunoreactivities in the nerve fibers were reduced, probably as a result of the release of these peptides.",
journal = "Archives of Biological Sciences",
title = "Immunohistochemical evidence for the presence of a Vasoactive Intestinal Peptide, Neuropeptide Y, and Substance P, in rat adrenal cortex after acute heat stress",
number = "1",
volume = "65",
pages = "315-320",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_329"
}

Petrović-Kosanović, D., Ukropina, M., Čakić-Milošević, M., Budeč, M., Milošević, V.,& Koko, V.. (2013). Immunohistochemical evidence for the presence of a Vasoactive Intestinal Peptide, Neuropeptide Y, and Substance P, in rat adrenal cortex after acute heat stress. in Archives of Biological Sciences, 65(1), 315-320.
https://hdl.handle.net/21.15107/rcub_ibiss_329

Petrović-Kosanović D, Ukropina M, Čakić-Milošević M, Budeč M, Milošević V, Koko V. Immunohistochemical evidence for the presence of a Vasoactive Intestinal Peptide, Neuropeptide Y, and Substance P, in rat adrenal cortex after acute heat stress. in Archives of Biological Sciences. 2013;65(1):315-320.
https://hdl.handle.net/21.15107/rcub_ibiss_329 .

Petrović-Kosanović, Dragana, Ukropina, Mirela, Čakić-Milošević, Maja, Budeč, Mirela, Milošević, Verica, Koko, Vesna, "Immunohistochemical evidence for the presence of a Vasoactive Intestinal Peptide, Neuropeptide Y, and Substance P, in rat adrenal cortex after acute heat stress" in Archives of Biological Sciences, 65, no. 1 (2013):315-320,
https://hdl.handle.net/21.15107/rcub_ibiss_329 .