@article{
author = "Mitrović, Marko Jumake and Kitanović, Sara and Tatalović, Nikola and Todorović, Anastasija and Lazarević Macanović, Mirjana",
year = "2023",
abstract = "Numerous studies are based on the use of animal models; however, in bipedal and
tetrapedal organisms there are significant differences in the biomechanics of the spinal
column, which can significantly impair the quality and applicability of the results
obtained. The aim of this study is to obtain basic data on the morphometric parameters
of guinea pig lumbar vertebrae, the analysis of which will indicate the location of the
biggest mechanical load. The lumbar vertebra morphometry test was performed by
means of X-ray imageing obtained from 12 guinea pigs, with equal numbers of males
and females. The results of investigations show that guinea pig lumbar vertebrae have
an irregular trapezoid geometry and that the measured body lengths of L4 and L5 are
the largest. The height parameters determined in the medial level showed that L4 had
the most concave body. Moreover, L4 had the greatest depth of the spinal canal at the
same measurement level. Consequently, in guinea pigs, the greatest load is in the L4
region, unlike in humans, where, due to the axial load of the spinal column, the highest
pressure is exerted on the last lumbar vertebrae., Brojne studije su zasnovane na upotrebi animalnih modela, ipak, kod bipedalnih i tetrapedalnih
organizama postoje značajne razlike u biomehanici kičmenog stuba, koje
mogu značajno narušiti kvalitet i primenjivost dobijenih rezultata. Cilj ovog ispitivanja
je da se dobiju osnovni podaci o morfometrijskim parametrima lumbalnih pršljenova
zamoraca, čijom analizom će se ukazati na mesto najvećeg mehaničkog opterećenja.
Morfometrijsko ispitivanje lumbalnih pršljenova zamoraca je sprovedeno na rendgenskim
snimcima 12 jedinki, sa jednakim brojem mužjaka i ženki. Rezultati ispitivanja
pokazuju da lumbalni pršljenovi zamoraca imaju nepravilnu trapezoidnu geometriju i
da su izmerene dužine L4 i L5 najveće. Parametri visine određivani su u medijalnom
nivou i pokazali su da L4 ima najkonkavnije telo. Štaviše, L4 je imao najveću dubinu
kičmenog kanala na istom nivou merenja. Shodno tome, kod zamoraca je najveće opterećenje
u L4 regiji za razliku od ljudi, gde se usled aksijalnog opterećenja kičmenog
stuba najveći pritisak ostvaruje na poslednjim lumbalnim pršljenovima.",
publisher = "Belgrade: Faculty of Veterinary Medicine, University of Belgrade",
journal = "Acta Veterinaria",
title = "Radiological investigation of guinea pig (Cavia porcellus) lumbar vertebral morphology ‒ a biomechanical aspect",
number = "1",
volume = "73",
doi = "10.2478/acve-2023-0005",
pages = "55-70"
}
