TY  - JOUR
AU  - Sretenović, Jasmina
AU  - Živković, Vladimir
AU  - Srejović, Ivan
AU  - Ajdžanović, Vladimir
AU  - Ristić, Nataša
AU  - Trifunović, Miroljub
AU  - Pantović, Suzana
AU  - Jović, Slavoljub
AU  - Jakovljević, Vladimir
AU  - Bolevich, Sergey
AU  - Milosavljević, Zoran
AU  - Milošević, Verica
PY  - 2020
UR  - /core/journals/microscopy-and-microanalysis/article/immunohistomorphometric-and-hormonal-analysis-of-the-pituitary-gonadotropic-cells-after-application-of-the-nandrolone-decanoate-and-swimming-training-in-adult-male-rats/CB060C51EF744799F8CC8590E060CAB8
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3717
AB  - The aim of the study was to investigate the effects of chronic nandrolone decanoate treatment and/or swimming training on immunohistomorphometric parameters on rat pituitary gonadotropic cells. Male Wistar albino rats, 10 weeks old, were classified into four groups: control (T−N−), nandrolone (T−N+), swimming training (T+N−), and swimming training with nandrolone (T+N+). The T+ groups swam for 4 weeks, 1 h/day, 5 days/week. The N+ groups received nandrolone decanoate (20 mg/kg) once per week for 4 weeks. Pituitary tissue sections were processed and stained for immunohistochemical analysis and immunofluorescence. The volume density of luteinizing hormone (LH) cells was decreased by 48% in T−N+ and for 35% in the T+N+ group. The volume density of follicle-stimulating hormone (FSH) cells was decreased by 39% in T−N+ and for 30% in T+N+ compared to the control. Nandrolone alone, or combined with swimming training, decreased the number of LH/FSH cells compared to the control. The levels of the immunofluorescent signal of LH/FSH cells were increased in all experimental groups. Nandrolone alone decreased the serum level of LH by 17%, whereas swimming training alone increased FSH levels by 11% compared to the control. Serum levels of testosterone were increased in all experimental groups. Nandrolone alone, or combined with swimming training, decreased immunohistomorphometric parameters of gonadotropic cells, whereas the levels of immunofluorescent signal were increased.
PB  - Cambridge University Press (CUP)
T2  - Microscopy and Microanalysis
T1  - Immunohistomorphometric and Hormonal Analysis of the Pituitary Gonadotropic Cells After Application of the Nandrolone Decanoate and Swimming Training in Adult Male Rats
IS  - 4
VL  - 26
DO  - 10.1017/s143192762000166x
SP  - 699
EP  - 707
ER  - 

@article{
author = "Sretenović, Jasmina and Živković, Vladimir and Srejović, Ivan and Ajdžanović, Vladimir and Ristić, Nataša and Trifunović, Miroljub and Pantović, Suzana and Jović, Slavoljub and Jakovljević, Vladimir and Bolevich, Sergey and Milosavljević, Zoran and Milošević, Verica",
year = "2020",
abstract = "The aim of the study was to investigate the effects of chronic nandrolone decanoate treatment and/or swimming training on immunohistomorphometric parameters on rat pituitary gonadotropic cells. Male Wistar albino rats, 10 weeks old, were classified into four groups: control (T−N−), nandrolone (T−N+), swimming training (T+N−), and swimming training with nandrolone (T+N+). The T+ groups swam for 4 weeks, 1 h/day, 5 days/week. The N+ groups received nandrolone decanoate (20 mg/kg) once per week for 4 weeks. Pituitary tissue sections were processed and stained for immunohistochemical analysis and immunofluorescence. The volume density of luteinizing hormone (LH) cells was decreased by 48% in T−N+ and for 35% in the T+N+ group. The volume density of follicle-stimulating hormone (FSH) cells was decreased by 39% in T−N+ and for 30% in T+N+ compared to the control. Nandrolone alone, or combined with swimming training, decreased the number of LH/FSH cells compared to the control. The levels of the immunofluorescent signal of LH/FSH cells were increased in all experimental groups. Nandrolone alone decreased the serum level of LH by 17%, whereas swimming training alone increased FSH levels by 11% compared to the control. Serum levels of testosterone were increased in all experimental groups. Nandrolone alone, or combined with swimming training, decreased immunohistomorphometric parameters of gonadotropic cells, whereas the levels of immunofluorescent signal were increased.",
publisher = "Cambridge University Press (CUP)",
journal = "Microscopy and Microanalysis",
title = "Immunohistomorphometric and Hormonal Analysis of the Pituitary Gonadotropic Cells After Application of the Nandrolone Decanoate and Swimming Training in Adult Male Rats",
number = "4",
volume = "26",
doi = "10.1017/s143192762000166x",
pages = "699-707"
}

Sretenović, J., Živković, V., Srejović, I., Ajdžanović, V., Ristić, N., Trifunović, M., Pantović, S., Jović, S., Jakovljević, V., Bolevich, S., Milosavljević, Z.,& Milošević, V.. (2020). Immunohistomorphometric and Hormonal Analysis of the Pituitary Gonadotropic Cells After Application of the Nandrolone Decanoate and Swimming Training in Adult Male Rats. in Microscopy and Microanalysis
Cambridge University Press (CUP)., 26(4), 699-707.
https://doi.org/10.1017/s143192762000166x

Sretenović J, Živković V, Srejović I, Ajdžanović V, Ristić N, Trifunović M, Pantović S, Jović S, Jakovljević V, Bolevich S, Milosavljević Z, Milošević V. Immunohistomorphometric and Hormonal Analysis of the Pituitary Gonadotropic Cells After Application of the Nandrolone Decanoate and Swimming Training in Adult Male Rats. in Microscopy and Microanalysis. 2020;26(4):699-707.
doi:10.1017/s143192762000166x .

Sretenović, Jasmina, Živković, Vladimir, Srejović, Ivan, Ajdžanović, Vladimir, Ristić, Nataša, Trifunović, Miroljub, Pantović, Suzana, Jović, Slavoljub, Jakovljević, Vladimir, Bolevich, Sergey, Milosavljević, Zoran, Milošević, Verica, "Immunohistomorphometric and Hormonal Analysis of the Pituitary Gonadotropic Cells After Application of the Nandrolone Decanoate and Swimming Training in Adult Male Rats" in Microscopy and Microanalysis, 26, no. 4 (2020):699-707,
https://doi.org/10.1017/s143192762000166x . .