TY  - CONF
AU  - Santoro, Azzurra
AU  - Santolamazza, Federica
AU  - Cacciò, Simone
AU  - La Rosa, Giuseppina
AU  - Antolová, Daniela
AU  - Auer, Herbert
AU  - Bagrade, Guna
AU  - Bandelj, Petra
AU  - Basso, Walter
AU  - Beck, Relja
AU  - Citterio, Carlo Vittorio
AU  - Davidson, Rebecca
AU  - Deksne, Gunita
AU  - Frey, Caroline
AU  - Fuglei, Eva
AU  - Glawischnig, Walter
AU  - Gottstein, Bruno
AU  - Harna, Jiri
AU  - Petersen, Heidi
AU  - Karamon, Jacek
AU  - Jansen, Famke
AU  - Jarošová, Júlia
AU  - Jokelainen, Pikka
AU  - Lundström-Stadelmann, Britta
AU  - Maksimov, Pavlo
AU  - Miljević, Milan
AU  - Miterpáková, Martina
AU  - Moks, Epp
AU  - Origgi, Francesco
AU  - Ozolina, Zanda
AU  - Ryser, Marie-Pierre
AU  - Romig, Thomas
AU  - Šarkūnas, Mindaugas
AU  - Scorrano, Nathalie
AU  - Saarma, Urmas
AU  - Šnábel, Viliam
AU  - Sréter, Tamas
AU  - Umhang, Gerald
AU  - Vengušt, Gorzad
AU  - Žele Vengušt, Diana
AU  - Vergles Rataj, Aleksandra
AU  - Casulli, Adriano
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6406
AB  - The cestode Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a highly fatal zoonotic parasitic disease of the northern hemisphere [1]. Red foxes are the main reservoir hosts and, probably, the main drivers of the geographic spreading of the disease in Europe. Knowledge of genetic relationship among E. multilocularis isolates at European scale is a key to understand the dispersal characteristics of E. multilocularis [2,3]. Hence, the present study aimed to describe the genetic diversity of E. multilocularis isolates obtained from different hosts in 19 European countries. Based on the analysis of complete nucleotide sequences of the cob, atp6, nad2, nad1 and cox1 mitochondrial genes (4,968 bp), 43 haplotypes were inferred. Four haplotypes represented 62.56% of the examined isolates (142/227), and one of these four haplotypes was found in each country investigated, except Svalbard (Norway). While the haplotypes from Svalbard were markedly different from all the others, mainland Europe appeared to be dominated by two main clusters, represented by most western-central-eastern European countries, and the Baltic countries including North-East Poland, respectively. Further comparison was made with the cob, nad2 and cox1 Nakao’s historical haplotypes [4], unveiling the presence of one Asian-like haplotype identified in Latvia and North-Eastern Poland. To better elucidate the presence of Asian genetic variants of E. multilocularis in Europe, and to get a more comprehensive European wide coverage, further studies, including endemic regions not investigated in the present study, especially some Eastern European countries, are needed.
PB  - Bishkek: Kyrgyz State Medical Academy named after I.K. Akhunbaev
C3  - Collection of abstracts: 29th World Congress of Echinococcosis; 2023 Ag 28-30; Bishkek, Kyrgyzstan
T1  - The genetic diversity of echinococcus multilocularis in europe: a picture based on mitochondrial markers
SP  - 72
EP  - 73
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_6406
ER  - 

@conference{
author = "Santoro, Azzurra and Santolamazza, Federica and Cacciò, Simone and La Rosa, Giuseppina and Antolová, Daniela and Auer, Herbert and Bagrade, Guna and Bandelj, Petra and Basso, Walter and Beck, Relja and Citterio, Carlo Vittorio and Davidson, Rebecca and Deksne, Gunita and Frey, Caroline and Fuglei, Eva and Glawischnig, Walter and Gottstein, Bruno and Harna, Jiri and Petersen, Heidi and Karamon, Jacek and Jansen, Famke and Jarošová, Júlia and Jokelainen, Pikka and Lundström-Stadelmann, Britta and Maksimov, Pavlo and Miljević, Milan and Miterpáková, Martina and Moks, Epp and Origgi, Francesco and Ozolina, Zanda and Ryser, Marie-Pierre and Romig, Thomas and Šarkūnas, Mindaugas and Scorrano, Nathalie and Saarma, Urmas and Šnábel, Viliam and Sréter, Tamas and Umhang, Gerald and Vengušt, Gorzad and Žele Vengušt, Diana and Vergles Rataj, Aleksandra and Casulli, Adriano",
year = "2023",
abstract = "The cestode Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a highly fatal zoonotic parasitic disease of the northern hemisphere [1]. Red foxes are the main reservoir hosts and, probably, the main drivers of the geographic spreading of the disease in Europe. Knowledge of genetic relationship among E. multilocularis isolates at European scale is a key to understand the dispersal characteristics of E. multilocularis [2,3]. Hence, the present study aimed to describe the genetic diversity of E. multilocularis isolates obtained from different hosts in 19 European countries. Based on the analysis of complete nucleotide sequences of the cob, atp6, nad2, nad1 and cox1 mitochondrial genes (4,968 bp), 43 haplotypes were inferred. Four haplotypes represented 62.56% of the examined isolates (142/227), and one of these four haplotypes was found in each country investigated, except Svalbard (Norway). While the haplotypes from Svalbard were markedly different from all the others, mainland Europe appeared to be dominated by two main clusters, represented by most western-central-eastern European countries, and the Baltic countries including North-East Poland, respectively. Further comparison was made with the cob, nad2 and cox1 Nakao’s historical haplotypes [4], unveiling the presence of one Asian-like haplotype identified in Latvia and North-Eastern Poland. To better elucidate the presence of Asian genetic variants of E. multilocularis in Europe, and to get a more comprehensive European wide coverage, further studies, including endemic regions not investigated in the present study, especially some Eastern European countries, are needed.",
publisher = "Bishkek: Kyrgyz State Medical Academy named after I.K. Akhunbaev",
journal = "Collection of abstracts: 29th World Congress of Echinococcosis; 2023 Ag 28-30; Bishkek, Kyrgyzstan",
title = "The genetic diversity of echinococcus multilocularis in europe: a picture based on mitochondrial markers",
pages = "72-73",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6406"
}

Santoro, A., Santolamazza, F., Cacciò, S., La Rosa, G., Antolová, D., Auer, H., Bagrade, G., Bandelj, P., Basso, W., Beck, R., Citterio, C. V., Davidson, R., Deksne, G., Frey, C., Fuglei, E., Glawischnig, W., Gottstein, B., Harna, J., Petersen, H., Karamon, J., Jansen, F., Jarošová, J., Jokelainen, P., Lundström-Stadelmann, B., Maksimov, P., Miljević, M., Miterpáková, M., Moks, E., Origgi, F., Ozolina, Z., Ryser, M., Romig, T., Šarkūnas, M., Scorrano, N., Saarma, U., Šnábel, V., Sréter, T., Umhang, G., Vengušt, G., Žele Vengušt, D., Vergles Rataj, A.,& Casulli, A.. (2023). The genetic diversity of echinococcus multilocularis in europe: a picture based on mitochondrial markers. in Collection of abstracts: 29th World Congress of Echinococcosis; 2023 Ag 28-30; Bishkek, Kyrgyzstan
Bishkek: Kyrgyz State Medical Academy named after I.K. Akhunbaev., 72-73.
https://hdl.handle.net/21.15107/rcub_ibiss_6406

Santoro A, Santolamazza F, Cacciò S, La Rosa G, Antolová D, Auer H, Bagrade G, Bandelj P, Basso W, Beck R, Citterio CV, Davidson R, Deksne G, Frey C, Fuglei E, Glawischnig W, Gottstein B, Harna J, Petersen H, Karamon J, Jansen F, Jarošová J, Jokelainen P, Lundström-Stadelmann B, Maksimov P, Miljević M, Miterpáková M, Moks E, Origgi F, Ozolina Z, Ryser M, Romig T, Šarkūnas M, Scorrano N, Saarma U, Šnábel V, Sréter T, Umhang G, Vengušt G, Žele Vengušt D, Vergles Rataj A, Casulli A. The genetic diversity of echinococcus multilocularis in europe: a picture based on mitochondrial markers. in Collection of abstracts: 29th World Congress of Echinococcosis; 2023 Ag 28-30; Bishkek, Kyrgyzstan. 2023;:72-73.
https://hdl.handle.net/21.15107/rcub_ibiss_6406 .

Santoro, Azzurra, Santolamazza, Federica, Cacciò, Simone, La Rosa, Giuseppina, Antolová, Daniela, Auer, Herbert, Bagrade, Guna, Bandelj, Petra, Basso, Walter, Beck, Relja, Citterio, Carlo Vittorio, Davidson, Rebecca, Deksne, Gunita, Frey, Caroline, Fuglei, Eva, Glawischnig, Walter, Gottstein, Bruno, Harna, Jiri, Petersen, Heidi, Karamon, Jacek, Jansen, Famke, Jarošová, Júlia, Jokelainen, Pikka, Lundström-Stadelmann, Britta, Maksimov, Pavlo, Miljević, Milan, Miterpáková, Martina, Moks, Epp, Origgi, Francesco, Ozolina, Zanda, Ryser, Marie-Pierre, Romig, Thomas, Šarkūnas, Mindaugas, Scorrano, Nathalie, Saarma, Urmas, Šnábel, Viliam, Sréter, Tamas, Umhang, Gerald, Vengušt, Gorzad, Žele Vengušt, Diana, Vergles Rataj, Aleksandra, Casulli, Adriano, "The genetic diversity of echinococcus multilocularis in europe: a picture based on mitochondrial markers" in Collection of abstracts: 29th World Congress of Echinococcosis; 2023 Ag 28-30; Bishkek, Kyrgyzstan (2023):72-73,
https://hdl.handle.net/21.15107/rcub_ibiss_6406 .