Rasić-Milutinović, Zorica R

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Relation of CuZnSOD activity with renal insufficiency in hypertensive diabetic patients

Stančić, Ana; Rasić-Milutinović, Zorica R; Perunicić-Peković, Gordana B; Buzadžić, Biljana J.; Korac, Aleksandra B; Otašević, Vesna; Janković, Aleksandra; Vučetić, Milica; Korać, Bato

(2012)

TY  - JOUR
AU  - Stančić, Ana
AU  - Rasić-Milutinović, Zorica R
AU  - Perunicić-Peković, Gordana B
AU  - Buzadžić, Biljana J.
AU  - Korac, Aleksandra B
AU  - Otašević, Vesna
AU  - Janković, Aleksandra
AU  - Vučetić, Milica
AU  - Korać, Bato
PY  - 2012
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1189
AB  - Diabetes and renal insufficiency are interrelated metabolic disorders closely associated with redox homeostasis disturbances. The aim of this study was to compare the activity of copper zinc,superoxide dismutase (CuZnSOD) in the erythrocytes of hypertensive diabetic patients with or without renal insufficiency with normal healthy control subjects. In both groups of diabetic patients, blood glucose level and the content of glycosylated hemoglobin (HbA(lc)) were higher than in the control group. However, CuZnSOD activity was significantly higher than control only in hypertensive diabetic patients with renal insufficiency. Our results suggest that disturbances in superoxide homeostasis do correlate with long-term complication in diabetes, i.e. diabetic renal insufficiency and hypertension.
T2  - Indian Journal of Biochemistry & Biophysics
T1  - Relation of CuZnSOD activity with renal insufficiency in hypertensive diabetic patients
IS  - 2
VL  - 49
EP  - 100
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1189
ER  - 
@article{
author = "Stančić, Ana and Rasić-Milutinović, Zorica R and Perunicić-Peković, Gordana B and Buzadžić, Biljana J. and Korac, Aleksandra B and Otašević, Vesna and Janković, Aleksandra and Vučetić, Milica and Korać, Bato",
year = "2012",
abstract = "Diabetes and renal insufficiency are interrelated metabolic disorders closely associated with redox homeostasis disturbances. The aim of this study was to compare the activity of copper zinc,superoxide dismutase (CuZnSOD) in the erythrocytes of hypertensive diabetic patients with or without renal insufficiency with normal healthy control subjects. In both groups of diabetic patients, blood glucose level and the content of glycosylated hemoglobin (HbA(lc)) were higher than in the control group. However, CuZnSOD activity was significantly higher than control only in hypertensive diabetic patients with renal insufficiency. Our results suggest that disturbances in superoxide homeostasis do correlate with long-term complication in diabetes, i.e. diabetic renal insufficiency and hypertension.",
journal = "Indian Journal of Biochemistry & Biophysics",
title = "Relation of CuZnSOD activity with renal insufficiency in hypertensive diabetic patients",
number = "2",
volume = "49",
pages = "100",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1189"
}
Stančić, A., Rasić-Milutinović, Z. R., Perunicić-Peković, G. B., Buzadžić, B. J., Korac, A. B., Otašević, V., Janković, A., Vučetić, M.,& Korać, B.. (2012). Relation of CuZnSOD activity with renal insufficiency in hypertensive diabetic patients. in Indian Journal of Biochemistry & Biophysics, 49(2).
https://hdl.handle.net/21.15107/rcub_ibiss_1189
Stančić A, Rasić-Milutinović ZR, Perunicić-Peković GB, Buzadžić BJ, Korac AB, Otašević V, Janković A, Vučetić M, Korać B. Relation of CuZnSOD activity with renal insufficiency in hypertensive diabetic patients. in Indian Journal of Biochemistry & Biophysics. 2012;49(2):null-100.
https://hdl.handle.net/21.15107/rcub_ibiss_1189 .
Stančić, Ana, Rasić-Milutinović, Zorica R, Perunicić-Peković, Gordana B, Buzadžić, Biljana J., Korac, Aleksandra B, Otašević, Vesna, Janković, Aleksandra, Vučetić, Milica, Korać, Bato, "Relation of CuZnSOD activity with renal insufficiency in hypertensive diabetic patients" in Indian Journal of Biochemistry & Biophysics, 49, no. 2 (2012),
https://hdl.handle.net/21.15107/rcub_ibiss_1189 .