TY  - JOUR
AU  - Dimkić, Ivica
AU  - Fira, Đorđe
AU  - Janakiev, Tamara
AU  - Kabić, Jovana
AU  - Stupar, Miloš
AU  - Nenadić, Marija
AU  - Unković, Nikola
AU  - Ljaljević Grbić, Milica
PY  - 2021
UR  - internal-pdf://Dimkić et al. - 2021 - The microbiome of bat guano for what is this knowledge important.pdf
UR  - https://doi.org/10.1007/s00253-021-11143-y
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4140
AB  - Abstract: Bats as flying mammals are potent vectors and natural reservoir hosts for many infectious viruses, bacteria, and fungi, also detected in their excreta such as guano. Accelerated deforestation, urbanization, and anthropization hastily lead to overpopulation of the bats in urban areas allowing easy interaction with other animals, expansion, and emergence of new zoonotic disease outbreaks potentially harmful to humans. Therefore, getting new insights in the microbiome of bat guano from different places represents an imperative for the future. Furthermore, the use of novel high-throughput sequencing technologies allows better insight in guano microbiome and potentially indicated that some species could be typical guano-dwelling members. Bats are well known as a natural reservoir of many zoonotic viruses such as Ebola, Nipah, Marburg, lyssaviruses, rabies, henipaviruses, and many coronaviruses which caused a high number of outbreaks including ongoing COVID-19 pandemic. Additionally, many bacterial and fungal pathogens were identified as common guano residents. Thus, the presence of multi-drug-resistant bacteria as environmental reservoirs of extended spectrum β-lactamases and carbapenemase-producing strains has been confirmed. Bat guano is the most suitable substrate for fungal reproduction and dissemination, including pathogenic yeasts and keratinophilic and dimorphic human pathogenic fungi known as notorious causative agents of severe endemic mycoses like histoplasmosis and fatal cryptococcosis, especially deadly in immunocompromised individuals. This review provides an overview of bat guano microbiota diversity and the significance of autochthonous and pathogenic taxa for humans and the environment, highlighting better understanding in preventing emerging diseases. Key points: Bat guano as reservoir and source for spreading of autochthonous and pathogenic microbiotaBat guano vs. novel zoonotic disease outbreaksDestruction of bat natural habitats urgently demands increased human awareness.
PB  - Springer Science and Business Media Deutschland GmbH
T2  - Applied Microbiology and Biotechnology
T1  - The microbiome of bat guano: for what is this knowledge important?
IS  - 4
VL  - 105
DO  - 10.1007/s00253-021-11143-y
SP  - 1407
EP  - 1419
ER  - 

@article{
author = "Dimkić, Ivica and Fira, Đorđe and Janakiev, Tamara and Kabić, Jovana and Stupar, Miloš and Nenadić, Marija and Unković, Nikola and Ljaljević Grbić, Milica",
year = "2021",
abstract = "Abstract: Bats as flying mammals are potent vectors and natural reservoir hosts for many infectious viruses, bacteria, and fungi, also detected in their excreta such as guano. Accelerated deforestation, urbanization, and anthropization hastily lead to overpopulation of the bats in urban areas allowing easy interaction with other animals, expansion, and emergence of new zoonotic disease outbreaks potentially harmful to humans. Therefore, getting new insights in the microbiome of bat guano from different places represents an imperative for the future. Furthermore, the use of novel high-throughput sequencing technologies allows better insight in guano microbiome and potentially indicated that some species could be typical guano-dwelling members. Bats are well known as a natural reservoir of many zoonotic viruses such as Ebola, Nipah, Marburg, lyssaviruses, rabies, henipaviruses, and many coronaviruses which caused a high number of outbreaks including ongoing COVID-19 pandemic. Additionally, many bacterial and fungal pathogens were identified as common guano residents. Thus, the presence of multi-drug-resistant bacteria as environmental reservoirs of extended spectrum β-lactamases and carbapenemase-producing strains has been confirmed. Bat guano is the most suitable substrate for fungal reproduction and dissemination, including pathogenic yeasts and keratinophilic and dimorphic human pathogenic fungi known as notorious causative agents of severe endemic mycoses like histoplasmosis and fatal cryptococcosis, especially deadly in immunocompromised individuals. This review provides an overview of bat guano microbiota diversity and the significance of autochthonous and pathogenic taxa for humans and the environment, highlighting better understanding in preventing emerging diseases. Key points: Bat guano as reservoir and source for spreading of autochthonous and pathogenic microbiotaBat guano vs. novel zoonotic disease outbreaksDestruction of bat natural habitats urgently demands increased human awareness.",
publisher = "Springer Science and Business Media Deutschland GmbH",
journal = "Applied Microbiology and Biotechnology",
title = "The microbiome of bat guano: for what is this knowledge important?",
number = "4",
volume = "105",
doi = "10.1007/s00253-021-11143-y",
pages = "1407-1419"
}

Dimkić, I., Fira, Đ., Janakiev, T., Kabić, J., Stupar, M., Nenadić, M., Unković, N.,& Ljaljević Grbić, M.. (2021). The microbiome of bat guano: for what is this knowledge important?. in Applied Microbiology and Biotechnology
Springer Science and Business Media Deutschland GmbH., 105(4), 1407-1419.
https://doi.org/10.1007/s00253-021-11143-y

Dimkić I, Fira Đ, Janakiev T, Kabić J, Stupar M, Nenadić M, Unković N, Ljaljević Grbić M. The microbiome of bat guano: for what is this knowledge important?. in Applied Microbiology and Biotechnology. 2021;105(4):1407-1419.
doi:10.1007/s00253-021-11143-y .

Dimkić, Ivica, Fira, Đorđe, Janakiev, Tamara, Kabić, Jovana, Stupar, Miloš, Nenadić, Marija, Unković, Nikola, Ljaljević Grbić, Milica, "The microbiome of bat guano: for what is this knowledge important?" in Applied Microbiology and Biotechnology, 105, no. 4 (2021):1407-1419,
https://doi.org/10.1007/s00253-021-11143-y . .