TY  - JOUR
AU  - Korićanac, G.
AU  - Đorđević, Ana
AU  - Žakula, Zorica
AU  - Vojnović-Milutinović, Danijela
AU  - Tepavčević, Snežana
AU  - Veličković, Nataša
AU  - Milosavljević, Tijana
AU  - Stojiljković, Mojca
AU  - Romić, Snježana
AU  - Matić, Gordana
PY  - 2013
PY  - 2013
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/335
AB  - We analyzed the effects of a fructose-rich diet (FRD) to test the assumption that the expression of metabolic syndrome phenotype is different in male and female rats. Two-way ANOVA revealed a significant effect of FRD on feeding behavior and carbohydrate/lipid metabolism. The increased caloric intake in FRD rats of both sexes was followed by a cluster of gender-specific changes typical for the metabolic syndrome. Female rats were characterized by decreased glycemia, increased triglycerides, enlarged visceral adipose tissue and increased absolute mass of liver, without changes in systolic blood pressure and insulin sensitivity. In contrast, male rats developed less disturbances in physical and biochemical characteristics, but blood pressure and insulin sensitivity were impaired by FRD. The results emphasize the detrimental effects of fructose consumption on cardiovascular risk and insulin action in males, whereas females are affected by other metabolic disturbances. These results support the idea of gender-dependent differences in the expression of the metabolic syndrome phenotype.
T2  - Archives of Biological Sciences
T1  - Gender modulates development of the metabolic syndrome phenotype in fructose-fed rats
IS  - 2
VL  - 65
SP  - 455
EP  - 464
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_335
ER  - 

@article{
author = "Korićanac, G. and Đorđević, Ana and Žakula, Zorica and Vojnović-Milutinović, Danijela and Tepavčević, Snežana and Veličković, Nataša and Milosavljević, Tijana and Stojiljković, Mojca and Romić, Snježana and Matić, Gordana",
year = "2013, 2013",
abstract = "We analyzed the effects of a fructose-rich diet (FRD) to test the assumption that the expression of metabolic syndrome phenotype is different in male and female rats. Two-way ANOVA revealed a significant effect of FRD on feeding behavior and carbohydrate/lipid metabolism. The increased caloric intake in FRD rats of both sexes was followed by a cluster of gender-specific changes typical for the metabolic syndrome. Female rats were characterized by decreased glycemia, increased triglycerides, enlarged visceral adipose tissue and increased absolute mass of liver, without changes in systolic blood pressure and insulin sensitivity. In contrast, male rats developed less disturbances in physical and biochemical characteristics, but blood pressure and insulin sensitivity were impaired by FRD. The results emphasize the detrimental effects of fructose consumption on cardiovascular risk and insulin action in males, whereas females are affected by other metabolic disturbances. These results support the idea of gender-dependent differences in the expression of the metabolic syndrome phenotype.",
journal = "Archives of Biological Sciences",
title = "Gender modulates development of the metabolic syndrome phenotype in fructose-fed rats",
number = "2",
volume = "65",
pages = "455-464",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_335"
}

Korićanac, G., Đorđević, A., Žakula, Z., Vojnović-Milutinović, D., Tepavčević, S., Veličković, N., Milosavljević, T., Stojiljković, M., Romić, S.,& Matić, G.. (2013). Gender modulates development of the metabolic syndrome phenotype in fructose-fed rats. in Archives of Biological Sciences, 65(2), 455-464.
https://hdl.handle.net/21.15107/rcub_ibiss_335

Korićanac G, Đorđević A, Žakula Z, Vojnović-Milutinović D, Tepavčević S, Veličković N, Milosavljević T, Stojiljković M, Romić S, Matić G. Gender modulates development of the metabolic syndrome phenotype in fructose-fed rats. in Archives of Biological Sciences. 2013;65(2):455-464.
https://hdl.handle.net/21.15107/rcub_ibiss_335 .

Korićanac, G., Đorđević, Ana, Žakula, Zorica, Vojnović-Milutinović, Danijela, Tepavčević, Snežana, Veličković, Nataša, Milosavljević, Tijana, Stojiljković, Mojca, Romić, Snježana, Matić, Gordana, "Gender modulates development of the metabolic syndrome phenotype in fructose-fed rats" in Archives of Biological Sciences, 65, no. 2 (2013):455-464,
https://hdl.handle.net/21.15107/rcub_ibiss_335 .