TY  - JOUR
AU  - Immonen, Elina
AU  - Sayadi, Ahmed
AU  - Stojković, Biljana
AU  - Savković, Uroš
AU  - Đorđević, Mirko
AU  - Liljestrand-Rönn, Johanna
AU  - Wiberg, Axel
AU  - Arnqvist, Göran
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5378
AB  - The patterns of reproductive timing and senescence vary within and across species owing to differences in reproductive strategies, but our understanding of the molecular underpinnings of such variation is incomplete. This is perhaps particularly true for sex differences. We investigated the evolution of sex-specific gene expression associated with life history divergence in replicated populations of the seed beetle Acanthoscelides obtectus, experimentally evolving under (E)arly or (L)ate life reproduction for >200 generations which has resulted in strongly divergent life histories. We detected 1,646 genes that were differentially expressed in E and L lines, consistent with a highly polygenic basis of life history evolution. Only 30% of differentially expressed genes were similarly affected in males and females. The evolution of long life was associated with significantly reduced sex differences in expression, especially in non-reproductive tissues. The expression differences were overall more pronounced in females, in accordance with their greater phenotypic divergence in lifespan. Functional enrichment analysis revealed differences between E and L beetles in gene categories previously implicated in aging, such as mitochondrial function and defense response. The results show that divergent life history evolution can be associated with profound changes in gene expression that alter the transcriptome in a sex-specific way, highlighting the importance of understanding the mechanisms of aging in each sex.
PB  - Oxford, UK: Oxford University Press
T2  - Genome Biology and Evolution
T1  - Experimental life history evolution results in sex-specific evolution of gene expression in seed beetles
IS  - 1
VL  - 15
DO  - 10.1093/gbe/evac177
SP  - evac177
ER  - 

@article{
author = "Immonen, Elina and Sayadi, Ahmed and Stojković, Biljana and Savković, Uroš and Đorđević, Mirko and Liljestrand-Rönn, Johanna and Wiberg, Axel and Arnqvist, Göran",
year = "2023",
abstract = "The patterns of reproductive timing and senescence vary within and across species owing to differences in reproductive strategies, but our understanding of the molecular underpinnings of such variation is incomplete. This is perhaps particularly true for sex differences. We investigated the evolution of sex-specific gene expression associated with life history divergence in replicated populations of the seed beetle Acanthoscelides obtectus, experimentally evolving under (E)arly or (L)ate life reproduction for >200 generations which has resulted in strongly divergent life histories. We detected 1,646 genes that were differentially expressed in E and L lines, consistent with a highly polygenic basis of life history evolution. Only 30% of differentially expressed genes were similarly affected in males and females. The evolution of long life was associated with significantly reduced sex differences in expression, especially in non-reproductive tissues. The expression differences were overall more pronounced in females, in accordance with their greater phenotypic divergence in lifespan. Functional enrichment analysis revealed differences between E and L beetles in gene categories previously implicated in aging, such as mitochondrial function and defense response. The results show that divergent life history evolution can be associated with profound changes in gene expression that alter the transcriptome in a sex-specific way, highlighting the importance of understanding the mechanisms of aging in each sex.",
publisher = "Oxford, UK: Oxford University Press",
journal = "Genome Biology and Evolution",
title = "Experimental life history evolution results in sex-specific evolution of gene expression in seed beetles",
number = "1",
volume = "15",
doi = "10.1093/gbe/evac177",
pages = "evac177"
}

Immonen, E., Sayadi, A., Stojković, B., Savković, U., Đorđević, M., Liljestrand-Rönn, J., Wiberg, A.,& Arnqvist, G.. (2023). Experimental life history evolution results in sex-specific evolution of gene expression in seed beetles. in Genome Biology and Evolution
Oxford, UK: Oxford University Press., 15(1), evac177.
https://doi.org/10.1093/gbe/evac177

Immonen E, Sayadi A, Stojković B, Savković U, Đorđević M, Liljestrand-Rönn J, Wiberg A, Arnqvist G. Experimental life history evolution results in sex-specific evolution of gene expression in seed beetles. in Genome Biology and Evolution. 2023;15(1):evac177.
doi:10.1093/gbe/evac177 .

Immonen, Elina, Sayadi, Ahmed, Stojković, Biljana, Savković, Uroš, Đorđević, Mirko, Liljestrand-Rönn, Johanna, Wiberg, Axel, Arnqvist, Göran, "Experimental life history evolution results in sex-specific evolution of gene expression in seed beetles" in Genome Biology and Evolution, 15, no. 1 (2023):evac177,
https://doi.org/10.1093/gbe/evac177 . .