TY  - JOUR
AU  - Veličković, Ivona
AU  - Žižak, Željko
AU  - Simin, Nataša
AU  - Bekvalac, Kristina
AU  - Ivanov, Marija
AU  - Soković, Marina
AU  - Marin, Petar D.
AU  - Grujić, Slavica
PY  - 2021
UR  - http://www.doiserbia.nb.rs/Article.aspx?ID=1821-21582102215V
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4690
AB  - The berries of Rubus discolor are considered a rich source of phytochemicals which could play an important role in the prevention of prevalent contemporary chronic diseases. Thus, the goal of the presented study was to determine the profile of phenolic acids and anthocyanins of aqueous and ethanol extracts of R. discolor fruit, and their free radical scavenging, antiproliferative, antidiabetic and antimicrobial activities. LC-MS/MS analyses confirmed the presence of 11 phenolic acids with protocatechuic and gallic acids being the major compounds. Additionally, cyanidin-glucoside/galactoside was the most abundant among the five identified anthocyanins. The ethanol extract was more efficient in scavenging free radicals than the aqueous extract. The absence of antiproliferative activity was observed for both extracts. However, they inhibited carbohydrate hydrolysing digestive enzymes associated with type-2 diabetes. Furthermore, the obtained results for α-glucosidase inhibitory activity (IC50 values 44.52 and 80.72 µg/mL, for the aqueous and ethanol extracts, respectively) indicate significantly higher activity than the positive control, Glucobay® (233.38 µg/mL). The ethanol extract was more effective against all of the examined bacteria (Bacillus cereus, Staphylococcus aureus and Enterobacter cloacae) than the aqueous extract. On the contrary, the aqueous extract showed better antifungal properties, particularly against Trihoderma viride and Penicillium verrucosum var. cyclopium. The quantified phenolics and presented bioactivities of R. discolor fruit extracts candidate them as a potential source of bioactive compounds which might be used in the food, pharmacy and cosmetic industries.
PB  - Belgrade: Institute of Botany and Botanical Garden Jevremovac
T2  - Botanica Serbica
T1  - Phenolic profile and biological potential of wild blackberry (Rubus discolor) fruits
IS  - 2
VL  - 45
DO  - 10.2298/BOTSERB2102215V
SP  - 215
EP  - 222
ER  - 

@article{
author = "Veličković, Ivona and Žižak, Željko and Simin, Nataša and Bekvalac, Kristina and Ivanov, Marija and Soković, Marina and Marin, Petar D. and Grujić, Slavica",
year = "2021",
abstract = "The berries of Rubus discolor are considered a rich source of phytochemicals which could play an important role in the prevention of prevalent contemporary chronic diseases. Thus, the goal of the presented study was to determine the profile of phenolic acids and anthocyanins of aqueous and ethanol extracts of R. discolor fruit, and their free radical scavenging, antiproliferative, antidiabetic and antimicrobial activities. LC-MS/MS analyses confirmed the presence of 11 phenolic acids with protocatechuic and gallic acids being the major compounds. Additionally, cyanidin-glucoside/galactoside was the most abundant among the five identified anthocyanins. The ethanol extract was more efficient in scavenging free radicals than the aqueous extract. The absence of antiproliferative activity was observed for both extracts. However, they inhibited carbohydrate hydrolysing digestive enzymes associated with type-2 diabetes. Furthermore, the obtained results for α-glucosidase inhibitory activity (IC50 values 44.52 and 80.72 µg/mL, for the aqueous and ethanol extracts, respectively) indicate significantly higher activity than the positive control, Glucobay® (233.38 µg/mL). The ethanol extract was more effective against all of the examined bacteria (Bacillus cereus, Staphylococcus aureus and Enterobacter cloacae) than the aqueous extract. On the contrary, the aqueous extract showed better antifungal properties, particularly against Trihoderma viride and Penicillium verrucosum var. cyclopium. The quantified phenolics and presented bioactivities of R. discolor fruit extracts candidate them as a potential source of bioactive compounds which might be used in the food, pharmacy and cosmetic industries.",
publisher = "Belgrade: Institute of Botany and Botanical Garden Jevremovac",
journal = "Botanica Serbica",
title = "Phenolic profile and biological potential of wild blackberry (Rubus discolor) fruits",
number = "2",
volume = "45",
doi = "10.2298/BOTSERB2102215V",
pages = "215-222"
}

Veličković, I., Žižak, Ž., Simin, N., Bekvalac, K., Ivanov, M., Soković, M., Marin, P. D.,& Grujić, S.. (2021). Phenolic profile and biological potential of wild blackberry (Rubus discolor) fruits. in Botanica Serbica
Belgrade: Institute of Botany and Botanical Garden Jevremovac., 45(2), 215-222.
https://doi.org/10.2298/BOTSERB2102215V

Veličković I, Žižak Ž, Simin N, Bekvalac K, Ivanov M, Soković M, Marin PD, Grujić S. Phenolic profile and biological potential of wild blackberry (Rubus discolor) fruits. in Botanica Serbica. 2021;45(2):215-222.
doi:10.2298/BOTSERB2102215V .

Veličković, Ivona, Žižak, Željko, Simin, Nataša, Bekvalac, Kristina, Ivanov, Marija, Soković, Marina, Marin, Petar D., Grujić, Slavica, "Phenolic profile and biological potential of wild blackberry (Rubus discolor) fruits" in Botanica Serbica, 45, no. 2 (2021):215-222,
https://doi.org/10.2298/BOTSERB2102215V . .

TY  - CONF
AU  - Tubić, Ljiljana
AU  - Simin, Nataša
AU  - Živković, Sanja
AU  - Bekvalac, Kristina
AU  - Savić, Jelena
AU  - Momčilović, Miloš
PY  - 2018
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5453
AB  - Chive (Allium schoenoprasum L.) is a small bulbous perennial which is used as a spice plant and
as a culinary herb. This plant contains compounds with potent antioxidant activity and has beneficial
effect on human health. Chive can be easily grown without special care. Accordingly, it would
be the best that people grow spice and healthy plants on their own balconies and terraces to have
fresh raw plant like chive every day. The objective of this study was to determine the impact of urban
environmental factors on the quality of chives planted at 5 different locations in Belgrade. The parameters of quality were phenolics profile and heavy metals content, while exposure to stress
was determined by measuring the activity of antioxidant enzymes, peroxidases (POX) and superoxide
dismutases (SOD) in fresh plants. The phenolics profile of plant aerial parts was characterized
by LC-MS/MS. Twelve phenolic compounds were quantified, among which kaempferol 3-O-glucoside
and quercetin 3-O-glucoside were dominant. Positive correlation between POX/SOD activity
and concentrations of the forementioned compounds was observed. The concentrations of Cd,
Cr, Cu, Pb and Zn in the leaves of investigated chives were measured using ICP-OES technique.
The levels of Cd in edible parts of chive at all investigated locations were higher than permissible
limit. Mean Cr concentration in leaves of chive was high only in central urban zone. The process of
urbanization has been expanded with the negative consequences on plants, which can be seen
from increased POX activity and high levels of heavy metals in leaves of chives.
PB  - Belgrade: Serbian Plant Physiology Society; Institute for Biological Research "Siniša Stanković"; Faculty of Biology
C3  - 3rd International Conference on Plant Biology (22nd SPPS Meeting); 2018 Jun 9-12; Belgrade, Serbia
T1  - Fresh chives in pots on the Belgrade’s balconies and terraces How do the urban environmental factors affect their quality?
SP  - 53
EP  - 54
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5453
ER  - 

@conference{
author = "Tubić, Ljiljana and Simin, Nataša and Živković, Sanja and Bekvalac, Kristina and Savić, Jelena and Momčilović, Miloš",
year = "2018",
abstract = "Chive (Allium schoenoprasum L.) is a small bulbous perennial which is used as a spice plant and
as a culinary herb. This plant contains compounds with potent antioxidant activity and has beneficial
effect on human health. Chive can be easily grown without special care. Accordingly, it would
be the best that people grow spice and healthy plants on their own balconies and terraces to have
fresh raw plant like chive every day. The objective of this study was to determine the impact of urban
environmental factors on the quality of chives planted at 5 different locations in Belgrade. The parameters of quality were phenolics profile and heavy metals content, while exposure to stress
was determined by measuring the activity of antioxidant enzymes, peroxidases (POX) and superoxide
dismutases (SOD) in fresh plants. The phenolics profile of plant aerial parts was characterized
by LC-MS/MS. Twelve phenolic compounds were quantified, among which kaempferol 3-O-glucoside
and quercetin 3-O-glucoside were dominant. Positive correlation between POX/SOD activity
and concentrations of the forementioned compounds was observed. The concentrations of Cd,
Cr, Cu, Pb and Zn in the leaves of investigated chives were measured using ICP-OES technique.
The levels of Cd in edible parts of chive at all investigated locations were higher than permissible
limit. Mean Cr concentration in leaves of chive was high only in central urban zone. The process of
urbanization has been expanded with the negative consequences on plants, which can be seen
from increased POX activity and high levels of heavy metals in leaves of chives.",
publisher = "Belgrade: Serbian Plant Physiology Society; Institute for Biological Research "Siniša Stanković"; Faculty of Biology",
journal = "3rd International Conference on Plant Biology (22nd SPPS Meeting); 2018 Jun 9-12; Belgrade, Serbia",
title = "Fresh chives in pots on the Belgrade’s balconies and terraces How do the urban environmental factors affect their quality?",
pages = "53-54",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5453"
}

Tubić, L., Simin, N., Živković, S., Bekvalac, K., Savić, J.,& Momčilović, M.. (2018). Fresh chives in pots on the Belgrade’s balconies and terraces How do the urban environmental factors affect their quality?. in 3rd International Conference on Plant Biology (22nd SPPS Meeting); 2018 Jun 9-12; Belgrade, Serbia
Belgrade: Serbian Plant Physiology Society; Institute for Biological Research "Siniša Stanković"; Faculty of Biology., 53-54.
https://hdl.handle.net/21.15107/rcub_ibiss_5453

Tubić L, Simin N, Živković S, Bekvalac K, Savić J, Momčilović M. Fresh chives in pots on the Belgrade’s balconies and terraces How do the urban environmental factors affect their quality?. in 3rd International Conference on Plant Biology (22nd SPPS Meeting); 2018 Jun 9-12; Belgrade, Serbia. 2018;:53-54.
https://hdl.handle.net/21.15107/rcub_ibiss_5453 .

Tubić, Ljiljana, Simin, Nataša, Živković, Sanja, Bekvalac, Kristina, Savić, Jelena, Momčilović, Miloš, "Fresh chives in pots on the Belgrade’s balconies and terraces How do the urban environmental factors affect their quality?" in 3rd International Conference on Plant Biology (22nd SPPS Meeting); 2018 Jun 9-12; Belgrade, Serbia (2018):53-54,
https://hdl.handle.net/21.15107/rcub_ibiss_5453 .