Giweli, Abdulhmid

Link to this page

https://radar.ibiss.bg.ac.rs/APP/faces/author.xhtml?author_id=0086c7e8-c2ee-41f6-8cfe-9d6579b9a446&item_offset=0&project_offset=0&sort_by=dc.date.issued
Authority KeyName Variants
0086c7e8-c2ee-41f6-8cfe-9d6579b9a446
  • Giweli, Abdulhmid (1)
  • Giweli, Abdulhmid A. (1)
Projects

Author's Bibliography

Leaves micromorphology, chemical profile, and bioactivity of in vitro-propagated Nepeta cyrenaica (Lamiaceae)

Alimpić-Aradski, Ana; Olađe Pavlović, Mariana; Janošević, Dušica; Todorović, Slađana; Gašić, Uroš; Mišić, Danijela; Pljevljakušić, Dejan; Šavikin, Katarina; Marin, Petar D.; Giweli, Abdulhmid; Duletić-Laušević, Sonja

(Hoboken: John Wiley and Sons, 2023) 

TY  - JOUR
AU  - Alimpić-Aradski, Ana
AU  - Olađe Pavlović, Mariana
AU  - Janošević, Dušica
AU  - Todorović, Slađana
AU  - Gašić, Uroš
AU  - Mišić, Danijela
AU  - Pljevljakušić, Dejan
AU  - Šavikin, Katarina
AU  - Marin, Petar D.
AU  - Giweli, Abdulhmid
AU  - Duletić-Laušević, Sonja
PY  - 2023
UR  - http://www3.interscience.wiley.com/cgi-bin/jhome/5152
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6445
AB  - Introduction: The endemic species Nepeta cyrenaica Quézel & Zaffran, native to northeastern Libya, is valued as an important honey-bearing plant.

Objectives: This study was aimed to examine the micromorphology, phytochemistry, and bioactivity of in vitro-propagated N. cyrenaica for the first time.

Materials and methods: The leaf indumentum was examined using light and scanning electron microscopy and further characterised for histochemistry. The chemical composition of essential oil (EO) was performed using GC-MS analysis, while dichloromethane (DCM), methanol (ME), ethanol (ET), and aqueous (AQ) extracts were analysed using qualitative and quantitative LC/MS analyses. The antioxidant activities of EO and extracts were assessed using three parallel assays, while enzyme-inhibiting effects were evaluated against four enzymes.

Results: The leaves bear various types of glandular trichomes, with lipophilic secretion predominating. The main EO component of EO was 1,8-cineole. A considerable number of phenolics and iridoids were tentatively identified in the ME extract. Quantitative LC/MS analysis confirmed that ferulic acid, rosmarinic acid, and epigallocatechin gallate were present in the highest amount in the extracts, in which three iridoids were also quantified. Although the ME extract contained the highest amount of polyphenolics and iridoids, the DCM extract showed the best overall biological potential. Additionally, EO exerted the strongest acetylcholinesterase and tyrosinase inhibition.

Conclusion: This study demonstrated that the endemic N. cyrenaica can be efficiently grown under in vitro conditions, where it develops various glandular trichomes that are thought to secrete and/or accumulate bioactive compounds with valuable medicinal potential.
PB  - Hoboken: John Wiley and Sons
T2  - Phytochemical Analysis
T1  - Leaves micromorphology, chemical profile, and bioactivity of in vitro-propagated Nepeta cyrenaica (Lamiaceae)
IS  - 6
VL  - 34
DO  - 10.1002/pca.3257
SP  - 661
EP  - 679
ER  - 
@article{
author = "Alimpić-Aradski, Ana and Olađe Pavlović, Mariana and Janošević, Dušica and Todorović, Slađana and Gašić, Uroš and Mišić, Danijela and Pljevljakušić, Dejan and Šavikin, Katarina and Marin, Petar D. and Giweli, Abdulhmid and Duletić-Laušević, Sonja",
year = "2023",
abstract = "Introduction: The endemic species Nepeta cyrenaica Quézel & Zaffran, native to northeastern Libya, is valued as an important honey-bearing plant.

Objectives: This study was aimed to examine the micromorphology, phytochemistry, and bioactivity of in vitro-propagated N. cyrenaica for the first time.

Materials and methods: The leaf indumentum was examined using light and scanning electron microscopy and further characterised for histochemistry. The chemical composition of essential oil (EO) was performed using GC-MS analysis, while dichloromethane (DCM), methanol (ME), ethanol (ET), and aqueous (AQ) extracts were analysed using qualitative and quantitative LC/MS analyses. The antioxidant activities of EO and extracts were assessed using three parallel assays, while enzyme-inhibiting effects were evaluated against four enzymes.

Results: The leaves bear various types of glandular trichomes, with lipophilic secretion predominating. The main EO component of EO was 1,8-cineole. A considerable number of phenolics and iridoids were tentatively identified in the ME extract. Quantitative LC/MS analysis confirmed that ferulic acid, rosmarinic acid, and epigallocatechin gallate were present in the highest amount in the extracts, in which three iridoids were also quantified. Although the ME extract contained the highest amount of polyphenolics and iridoids, the DCM extract showed the best overall biological potential. Additionally, EO exerted the strongest acetylcholinesterase and tyrosinase inhibition.

Conclusion: This study demonstrated that the endemic N. cyrenaica can be efficiently grown under in vitro conditions, where it develops various glandular trichomes that are thought to secrete and/or accumulate bioactive compounds with valuable medicinal potential.",
publisher = "Hoboken: John Wiley and Sons",
journal = "Phytochemical Analysis",
title = "Leaves micromorphology, chemical profile, and bioactivity of in vitro-propagated Nepeta cyrenaica (Lamiaceae)",
number = "6",
volume = "34",
doi = "10.1002/pca.3257",
pages = "661-679"
}
Alimpić-Aradski, A., Olađe Pavlović, M., Janošević, D., Todorović, S., Gašić, U., Mišić, D., Pljevljakušić, D., Šavikin, K., Marin, P. D., Giweli, A.,& Duletić-Laušević, S.. (2023). Leaves micromorphology, chemical profile, and bioactivity of in vitro-propagated Nepeta cyrenaica (Lamiaceae). in Phytochemical Analysis
Hoboken: John Wiley and Sons., 34(6), 661-679.
https://doi.org/10.1002/pca.3257
Alimpić-Aradski A, Olađe Pavlović M, Janošević D, Todorović S, Gašić U, Mišić D, Pljevljakušić D, Šavikin K, Marin PD, Giweli A, Duletić-Laušević S. Leaves micromorphology, chemical profile, and bioactivity of in vitro-propagated Nepeta cyrenaica (Lamiaceae). in Phytochemical Analysis. 2023;34(6):661-679.
doi:10.1002/pca.3257 .
Alimpić-Aradski, Ana, Olađe Pavlović, Mariana, Janošević, Dušica, Todorović, Slađana, Gašić, Uroš, Mišić, Danijela, Pljevljakušić, Dejan, Šavikin, Katarina, Marin, Petar D., Giweli, Abdulhmid, Duletić-Laušević, Sonja, "Leaves micromorphology, chemical profile, and bioactivity of in vitro-propagated Nepeta cyrenaica (Lamiaceae)" in Phytochemical Analysis, 34, no. 6 (2023):661-679,
https://doi.org/10.1002/pca.3257 . .

Composition and antimicrobial activity of essential oils of Artemisia judaica, A. herba-alba and A. arborescens from Libya

Janaćković, Peđa; Novaković, Jelica; Soković, Marina; Vujisić, Ljubodrag; Giweli, Abdulhmid A.; Dajić Stevanović, Zora; Marin, Petar D.

(2015) 

TY  - JOUR
AU  - Janaćković, Peđa
AU  - Novaković, Jelica
AU  - Soković, Marina
AU  - Vujisić, Ljubodrag
AU  - Giweli, Abdulhmid A.
AU  - Dajić Stevanović, Zora
AU  - Marin, Petar D.
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2052
AB  - The essential oils obtained by hydrodistillation from the aerial parts
   of Artemisia judaica L., Artemisia herbaalba Asso. and Artemisia
   arborescens L. (cultivated) from Libya, were analyzed by GC and GC-MS.
   The antimicrobial properties were determined using the broth
   microdilution method against eight bacterial species: Bacillus cereus
   (clinical isolate), Micrococcus flavus (ATCC10240), Listeria
   monocytogenes (NCTC7973), Staphylococcus aureus (ATCC6538), Escherichia
   coli (ATCC35210), Pseudomonas aeruginosa (ATCC27853), Salmonella
   typhimurium (ATCC13311), Enterobacter cloacae (human isolates) and eight
   fungal species: Aspergillus niger (ATCC6275), A. ochraceus (ATCC12066),
   A. versicolor (ATCC11730), A. fumigatus (ATCC1022), Penicillium
   ochrochloron (ATCC9112), P. funiculosum (ATCC10509), Trichoderma viride
   (IAM5061) and Candida albicans (human isolate). The major constituents
   of A. arborescens oil were sesquiterpene hydrocarbons (47.4\%).
   Oxygenated monoterpenes were the dominant constituents in the A. judaica
   and A. herba-alba oils (54.2\% and 77.3\%, respectively). Camphor
   (24.7\%) and chamazulene (20.9\%) were the major components in the
   essential oil of A. arborescens, chrysanthenone (20.8\%),
   cis-chrysanthenyl acetate (17.6\%) and cis-thujone (13.6\%) dominated in
   the A. herba-alba oil, and the major constituents in the A. judaica oil
   were piperitone (30.21\%) and cis-chrysanthenol (9.1\%). The best
   antimicrobial activity was obtained for A. judaica oil and the lowest
   effect was noticed in A. arborescens oil. The effect of the tested oils
   was higher against Gram (+) than Gram (-) bacteria. All three oils
   showed the best antibacterial activity against Listeria monocytogenes
   and the lowest against Pseudomonas aeruginosa, Escherichia coli,
   Enterobacter cloacae, compared to streptomycin and ampicillin. All three
   oils showed better antifungal activities than ketoconazole, except A.
   arborescens oil against Aspergillus niger.
T2  - Archives of Biological Sciences
T1  - Composition and antimicrobial activity of essential oils of Artemisia judaica, A. herba-alba and A. arborescens from Libya
IS  - 2
VL  - 67
DO  - 10.2298/ABS141203010J
SP  - 455
EP  - 466
ER  - 
@article{
author = "Janaćković, Peđa and Novaković, Jelica and Soković, Marina and Vujisić, Ljubodrag and Giweli, Abdulhmid A. and Dajić Stevanović, Zora and Marin, Petar D.",
year = "2015",
abstract = "The essential oils obtained by hydrodistillation from the aerial parts
   of Artemisia judaica L., Artemisia herbaalba Asso. and Artemisia
   arborescens L. (cultivated) from Libya, were analyzed by GC and GC-MS.
   The antimicrobial properties were determined using the broth
   microdilution method against eight bacterial species: Bacillus cereus
   (clinical isolate), Micrococcus flavus (ATCC10240), Listeria
   monocytogenes (NCTC7973), Staphylococcus aureus (ATCC6538), Escherichia
   coli (ATCC35210), Pseudomonas aeruginosa (ATCC27853), Salmonella
   typhimurium (ATCC13311), Enterobacter cloacae (human isolates) and eight
   fungal species: Aspergillus niger (ATCC6275), A. ochraceus (ATCC12066),
   A. versicolor (ATCC11730), A. fumigatus (ATCC1022), Penicillium
   ochrochloron (ATCC9112), P. funiculosum (ATCC10509), Trichoderma viride
   (IAM5061) and Candida albicans (human isolate). The major constituents
   of A. arborescens oil were sesquiterpene hydrocarbons (47.4\%).
   Oxygenated monoterpenes were the dominant constituents in the A. judaica
   and A. herba-alba oils (54.2\% and 77.3\%, respectively). Camphor
   (24.7\%) and chamazulene (20.9\%) were the major components in the
   essential oil of A. arborescens, chrysanthenone (20.8\%),
   cis-chrysanthenyl acetate (17.6\%) and cis-thujone (13.6\%) dominated in
   the A. herba-alba oil, and the major constituents in the A. judaica oil
   were piperitone (30.21\%) and cis-chrysanthenol (9.1\%). The best
   antimicrobial activity was obtained for A. judaica oil and the lowest
   effect was noticed in A. arborescens oil. The effect of the tested oils
   was higher against Gram (+) than Gram (-) bacteria. All three oils
   showed the best antibacterial activity against Listeria monocytogenes
   and the lowest against Pseudomonas aeruginosa, Escherichia coli,
   Enterobacter cloacae, compared to streptomycin and ampicillin. All three
   oils showed better antifungal activities than ketoconazole, except A.
   arborescens oil against Aspergillus niger.",
journal = "Archives of Biological Sciences",
title = "Composition and antimicrobial activity of essential oils of Artemisia judaica, A. herba-alba and A. arborescens from Libya",
number = "2",
volume = "67",
doi = "10.2298/ABS141203010J",
pages = "455-466"
}
Janaćković, P., Novaković, J., Soković, M., Vujisić, L., Giweli, A. A., Dajić Stevanović, Z.,& Marin, P. D.. (2015). Composition and antimicrobial activity of essential oils of Artemisia judaica, A. herba-alba and A. arborescens from Libya. in Archives of Biological Sciences, 67(2), 455-466.
https://doi.org/10.2298/ABS141203010J
Janaćković P, Novaković J, Soković M, Vujisić L, Giweli AA, Dajić Stevanović Z, Marin PD. Composition and antimicrobial activity of essential oils of Artemisia judaica, A. herba-alba and A. arborescens from Libya. in Archives of Biological Sciences. 2015;67(2):455-466.
doi:10.2298/ABS141203010J .
Janaćković, Peđa, Novaković, Jelica, Soković, Marina, Vujisić, Ljubodrag, Giweli, Abdulhmid A., Dajić Stevanović, Zora, Marin, Petar D., "Composition and antimicrobial activity of essential oils of Artemisia judaica, A. herba-alba and A. arborescens from Libya" in Archives of Biological Sciences, 67, no. 2 (2015):455-466,
https://doi.org/10.2298/ABS141203010J . .
3
37
25
36