TY  - CONF
AU  - Koračak, Ljiljana K.
AU  - Lupšić, Ema
AU  - Jovanović, Mirna
AU  - Novaković, Miroslav
AU  - Pešić, Milica
AU  - Opsenica, Igor M.
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6383
AB  - Značaj artemizinina i njegovih derivata se ogleda u biološkoj aktivnosti jer osim što su
našli primjenu kao efikasni lijekovi za liječenje malarije, pokazuju i antitumorsku
aktivnost. Pirimidinsko jezgro je važno zbog prisustva ovog strukturnog motiva u
prirodnim proizvodima, u odobrenim lijekovima, ali i u biološki aktivnim molekulima. U
okviru ovog istraživanja prijavljena je sinteza novih hibridnih molekula dobijenih
povezivanjem dvije farmakofore, kao i njihova antitumorska aktivnost na rezistentnim i
osjetljivim ćelijama nesitnoćelijskog karcinoma pluća.
AB  - In addition to being used for the effective treatment of malaria, artemisinin and derivatives also exhibit anticancer activity. The importance of the pyrimidine scaffold is evidenced by its presence in natural products and approved drugs, as well as in biologically active compounds. In this study, we report the synthesis of novel hybrid molecules comprising two pharmacophores and their activity against sensitive and multidrug‐resistant human non‐small cell lung carcinoma cells.
PB  - Belgrade: Serbian Chemical Society
C3  - Book of Abstracts and Proceedings: 59th meeting of the Serbian Chemical Society; 2023 Jun 1-2; Novi Sad, Serbia
T1  - Sinteza novih derivata artemizinina sa antitumorskom aktivnošću na rezistentne ćelije raka
T1  - Synthesis of novel artemisinin derivatives with anticancer activity against multidrug-resistant cancer cells
SP  - 70
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_6383
ER  - 

@conference{
author = "Koračak, Ljiljana K. and Lupšić, Ema and Jovanović, Mirna and Novaković, Miroslav and Pešić, Milica and Opsenica, Igor M.",
year = "2023",
abstract = "Značaj artemizinina i njegovih derivata se ogleda u biološkoj aktivnosti jer osim što su
našli primjenu kao efikasni lijekovi za liječenje malarije, pokazuju i antitumorsku
aktivnost. Pirimidinsko jezgro je važno zbog prisustva ovog strukturnog motiva u
prirodnim proizvodima, u odobrenim lijekovima, ali i u biološki aktivnim molekulima. U
okviru ovog istraživanja prijavljena je sinteza novih hibridnih molekula dobijenih
povezivanjem dvije farmakofore, kao i njihova antitumorska aktivnost na rezistentnim i
osjetljivim ćelijama nesitnoćelijskog karcinoma pluća., In addition to being used for the effective treatment of malaria, artemisinin and derivatives also exhibit anticancer activity. The importance of the pyrimidine scaffold is evidenced by its presence in natural products and approved drugs, as well as in biologically active compounds. In this study, we report the synthesis of novel hybrid molecules comprising two pharmacophores and their activity against sensitive and multidrug‐resistant human non‐small cell lung carcinoma cells.",
publisher = "Belgrade: Serbian Chemical Society",
journal = "Book of Abstracts and Proceedings: 59th meeting of the Serbian Chemical Society; 2023 Jun 1-2; Novi Sad, Serbia",
title = "Sinteza novih derivata artemizinina sa antitumorskom aktivnošću na rezistentne ćelije raka, Synthesis of novel artemisinin derivatives with anticancer activity against multidrug-resistant cancer cells",
pages = "70",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6383"
}

Koračak, L. K., Lupšić, E., Jovanović, M., Novaković, M., Pešić, M.,& Opsenica, I. M.. (2023). Sinteza novih derivata artemizinina sa antitumorskom aktivnošću na rezistentne ćelije raka. in Book of Abstracts and Proceedings: 59th meeting of the Serbian Chemical Society; 2023 Jun 1-2; Novi Sad, Serbia
Belgrade: Serbian Chemical Society., 70.
https://hdl.handle.net/21.15107/rcub_ibiss_6383

Koračak LK, Lupšić E, Jovanović M, Novaković M, Pešić M, Opsenica IM. Sinteza novih derivata artemizinina sa antitumorskom aktivnošću na rezistentne ćelije raka. in Book of Abstracts and Proceedings: 59th meeting of the Serbian Chemical Society; 2023 Jun 1-2; Novi Sad, Serbia. 2023;:70.
https://hdl.handle.net/21.15107/rcub_ibiss_6383 .

Koračak, Ljiljana K., Lupšić, Ema, Jovanović, Mirna, Novaković, Miroslav, Pešić, Milica, Opsenica, Igor M., "Sinteza novih derivata artemizinina sa antitumorskom aktivnošću na rezistentne ćelije raka" in Book of Abstracts and Proceedings: 59th meeting of the Serbian Chemical Society; 2023 Jun 1-2; Novi Sad, Serbia (2023):70,
https://hdl.handle.net/21.15107/rcub_ibiss_6383 .