TY  - CONF
AU  - Kračun-Kolarević, Margareta
AU  - Jovanović Marić, Jovana
AU  - Đorđević, Jelena
AU  - Sunjog, Karolina
AU  - Nikolić, Ivan
AU  - Marić, Ana
AU  - Ilić, Marija
AU  - Simonović, Predrag
AU  - Alygizakis, Nikiforos
AU  - Ng, Kelsey
AU  - Oswald, Peter
AU  - Slobodnik, Jaroslav
AU  - Žegura, Bojana
AU  - Vuković-Gačić, Branka
AU  - Paunović, Momir
AU  - Kolarević, Stoimir
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6592
AB  - Assessment of impact of pollution in the environmental studies requires multi-endpoints approach to properly
link cause and effects of pollution with focus on chemical pollution. In this sense systematic weight-of-evidence
approach (WoE) with multiple lines of evidence (LoEs) is preferable to apply. The WoE approach highlights the
importance to identify strengths and weaknesses of used LoEs. Therefore, in this study we have tested efficacy
of genotoxicological endpoints as one of the LoEs in the in situ assessment of pollution effects in the freshwater
ecosystems using Alburnus alburnus (bleak) as a bioindicator species. Additional LoEs that were used in the
study are: component-based methods for the assessment of SumTU in water based on monitoring data of the
Serbian Environmental Protection Agency (SEPA), effect based methods employing in vitro genotoxicological
analyses of Joint Danube Survey 4 (JDS4) water extracts and field derived species inventories for the
assessment and indication of ecological status/potential based on SEPA and JDS4 data. The study was
conducted within the JDS4 campaign at nine sampling sites at the Tisa, Sava, Velika Morava and Danube rivers
in the Republic of Serbia. In the case of three sampling sites, the results were uniform, meaning that all four
LoEs pointed to pollution pressure. The differences in the LoEs outcomes for other sites indicated the
importance of multiple LoEs approach for proper identification of ecological impact. In the case of current
study we have identified comet and micronucleus assay to be appropriate for the genotoxicological assessment
in the in situ studies due to high sensitivity in discrimination of sites in relation to pollution intensity, while
RAPD analysis to be more suitable for controlled ex situ investigations.
PB  - Austrian Committee - International Association for Danube Research
C3  - Conference Book: 44th IAD conference: Tackling Present & Future Environmental Challenges of a European Riverscape; 2023 Feb 6-9; Krems, Austria
T1  - In situ genotoxicity assessment in the weight-of-evidence approach – The Joint Danube Survey 4 case study
SP  - 18
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_6592
ER  - 

@conference{
author = "Kračun-Kolarević, Margareta and Jovanović Marić, Jovana and Đorđević, Jelena and Sunjog, Karolina and Nikolić, Ivan and Marić, Ana and Ilić, Marija and Simonović, Predrag and Alygizakis, Nikiforos and Ng, Kelsey and Oswald, Peter and Slobodnik, Jaroslav and Žegura, Bojana and Vuković-Gačić, Branka and Paunović, Momir and Kolarević, Stoimir",
year = "2023",
abstract = "Assessment of impact of pollution in the environmental studies requires multi-endpoints approach to properly
link cause and effects of pollution with focus on chemical pollution. In this sense systematic weight-of-evidence
approach (WoE) with multiple lines of evidence (LoEs) is preferable to apply. The WoE approach highlights the
importance to identify strengths and weaknesses of used LoEs. Therefore, in this study we have tested efficacy
of genotoxicological endpoints as one of the LoEs in the in situ assessment of pollution effects in the freshwater
ecosystems using Alburnus alburnus (bleak) as a bioindicator species. Additional LoEs that were used in the
study are: component-based methods for the assessment of SumTU in water based on monitoring data of the
Serbian Environmental Protection Agency (SEPA), effect based methods employing in vitro genotoxicological
analyses of Joint Danube Survey 4 (JDS4) water extracts and field derived species inventories for the
assessment and indication of ecological status/potential based on SEPA and JDS4 data. The study was
conducted within the JDS4 campaign at nine sampling sites at the Tisa, Sava, Velika Morava and Danube rivers
in the Republic of Serbia. In the case of three sampling sites, the results were uniform, meaning that all four
LoEs pointed to pollution pressure. The differences in the LoEs outcomes for other sites indicated the
importance of multiple LoEs approach for proper identification of ecological impact. In the case of current
study we have identified comet and micronucleus assay to be appropriate for the genotoxicological assessment
in the in situ studies due to high sensitivity in discrimination of sites in relation to pollution intensity, while
RAPD analysis to be more suitable for controlled ex situ investigations.",
publisher = "Austrian Committee - International Association for Danube Research",
journal = "Conference Book: 44th IAD conference: Tackling Present & Future Environmental Challenges of a European Riverscape; 2023 Feb 6-9; Krems, Austria",
title = "In situ genotoxicity assessment in the weight-of-evidence approach – The Joint Danube Survey 4 case study",
pages = "18",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6592"
}

Kračun-Kolarević, M., Jovanović Marić, J., Đorđević, J., Sunjog, K., Nikolić, I., Marić, A., Ilić, M., Simonović, P., Alygizakis, N., Ng, K., Oswald, P., Slobodnik, J., Žegura, B., Vuković-Gačić, B., Paunović, M.,& Kolarević, S.. (2023). In situ genotoxicity assessment in the weight-of-evidence approach – The Joint Danube Survey 4 case study. in Conference Book: 44th IAD conference: Tackling Present & Future Environmental Challenges of a European Riverscape; 2023 Feb 6-9; Krems, Austria
Austrian Committee - International Association for Danube Research., 18.
https://hdl.handle.net/21.15107/rcub_ibiss_6592

Kračun-Kolarević M, Jovanović Marić J, Đorđević J, Sunjog K, Nikolić I, Marić A, Ilić M, Simonović P, Alygizakis N, Ng K, Oswald P, Slobodnik J, Žegura B, Vuković-Gačić B, Paunović M, Kolarević S. In situ genotoxicity assessment in the weight-of-evidence approach – The Joint Danube Survey 4 case study. in Conference Book: 44th IAD conference: Tackling Present & Future Environmental Challenges of a European Riverscape; 2023 Feb 6-9; Krems, Austria. 2023;:18.
https://hdl.handle.net/21.15107/rcub_ibiss_6592 .

Kračun-Kolarević, Margareta, Jovanović Marić, Jovana, Đorđević, Jelena, Sunjog, Karolina, Nikolić, Ivan, Marić, Ana, Ilić, Marija, Simonović, Predrag, Alygizakis, Nikiforos, Ng, Kelsey, Oswald, Peter, Slobodnik, Jaroslav, Žegura, Bojana, Vuković-Gačić, Branka, Paunović, Momir, Kolarević, Stoimir, "In situ genotoxicity assessment in the weight-of-evidence approach – The Joint Danube Survey 4 case study" in Conference Book: 44th IAD conference: Tackling Present & Future Environmental Challenges of a European Riverscape; 2023 Feb 6-9; Krems, Austria (2023):18,
https://hdl.handle.net/21.15107/rcub_ibiss_6592 .

TY  - JOUR
AU  - Jovanović Marić, Jovana
AU  - Kolarević, Stoimir
AU  - Đorđević, Jelena
AU  - Sunjog, Karolina
AU  - Nikolić, Ivan
AU  - Marić, Ana
AU  - Ilić, Marija
AU  - Simonović, Predrag
AU  - Alygizakis, Nikiforos
AU  - Ng, Kelsey
AU  - Oswald, Peter
AU  - Slobodnik, Jaroslav
AU  - Žegura, Bojana
AU  - Vuković-Gačić, Branka
AU  - Paunović, Momir
AU  - Kračun-Kolarević, Margareta
PY  - 2023
UR  - https://academic.oup.com/mutage/advance-article/doi/10.1093/mutage/geac024/6823671
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5243
AB  - Environmental studies which aim to assess the ecological impact of chemical and other types of pollution should employ a complex weight-of-evidence approach with multiple lines of evidence (LoEs). This study focused on in situ genotoxicological methods such as the comet and micronucleus assays and randomly amplified polymorphic DNA analysis as one of the multiple LoEs (LoE3) on the fish species Alburnus alburnus (bleak) as a bioindicator. The study was carried out within the Joint Danube Survey 4 (JDS4) at nine sites in the Danube River Basin in the Republic of Serbia. Out of nine sampling sites, two were situated at the Tisa, Sava, and Velika Morava rivers, and three sites were at the Danube River. The three additionally employed LoEs were: SumTUwater calculated based on the monitoring data in the database of the Serbian Environmental Protection Agency (SEPA) (LoE1); in vitro analyses of JDS4 water extracts employing genotoxicological methods (LoE2); assessment of the ecological status/potential by SEPA and indication of the ecological status for the sites performed within the JDS4 (LoE4). The analyzed biomarker responses in the bleak were integrated into the unique integrated biomarker response index which was used to rank the sites. The highest pollution pressure was recorded at JDS4 39 and JDS4 36, while the lowest was at JDS4 35. The impact of pollution was confirmed at three sites, JDS4 33, 40, and 41, by all four LoEs. At other sampling sites, a difference was observed regarding the pollution depending on the employed LoEs. This indicates the importance of implementing a comprehensive weight-of-evidence approach to ensure the impact of pollution is not overlooked when using only one LoE as is often the case in environmental studies.
PB  - Oxford: Oxford University Press
T2  - Mutagenesis
T1  - In situ detection of the genotoxic potential as one of the lines of evidence in the weight-of-evidence approach—the Joint Danube Survey 4 Case Study
IS  - 1
VL  - 38
DO  - 10.1093/mutage/geac024
SP  - 21
EP  - 32
ER  - 

@article{
author = "Jovanović Marić, Jovana and Kolarević, Stoimir and Đorđević, Jelena and Sunjog, Karolina and Nikolić, Ivan and Marić, Ana and Ilić, Marija and Simonović, Predrag and Alygizakis, Nikiforos and Ng, Kelsey and Oswald, Peter and Slobodnik, Jaroslav and Žegura, Bojana and Vuković-Gačić, Branka and Paunović, Momir and Kračun-Kolarević, Margareta",
year = "2023",
abstract = "Environmental studies which aim to assess the ecological impact of chemical and other types of pollution should employ a complex weight-of-evidence approach with multiple lines of evidence (LoEs). This study focused on in situ genotoxicological methods such as the comet and micronucleus assays and randomly amplified polymorphic DNA analysis as one of the multiple LoEs (LoE3) on the fish species Alburnus alburnus (bleak) as a bioindicator. The study was carried out within the Joint Danube Survey 4 (JDS4) at nine sites in the Danube River Basin in the Republic of Serbia. Out of nine sampling sites, two were situated at the Tisa, Sava, and Velika Morava rivers, and three sites were at the Danube River. The three additionally employed LoEs were: SumTUwater calculated based on the monitoring data in the database of the Serbian Environmental Protection Agency (SEPA) (LoE1); in vitro analyses of JDS4 water extracts employing genotoxicological methods (LoE2); assessment of the ecological status/potential by SEPA and indication of the ecological status for the sites performed within the JDS4 (LoE4). The analyzed biomarker responses in the bleak were integrated into the unique integrated biomarker response index which was used to rank the sites. The highest pollution pressure was recorded at JDS4 39 and JDS4 36, while the lowest was at JDS4 35. The impact of pollution was confirmed at three sites, JDS4 33, 40, and 41, by all four LoEs. At other sampling sites, a difference was observed regarding the pollution depending on the employed LoEs. This indicates the importance of implementing a comprehensive weight-of-evidence approach to ensure the impact of pollution is not overlooked when using only one LoE as is often the case in environmental studies.",
publisher = "Oxford: Oxford University Press",
journal = "Mutagenesis",
title = "In situ detection of the genotoxic potential as one of the lines of evidence in the weight-of-evidence approach—the Joint Danube Survey 4 Case Study",
number = "1",
volume = "38",
doi = "10.1093/mutage/geac024",
pages = "21-32"
}

Jovanović Marić, J., Kolarević, S., Đorđević, J., Sunjog, K., Nikolić, I., Marić, A., Ilić, M., Simonović, P., Alygizakis, N., Ng, K., Oswald, P., Slobodnik, J., Žegura, B., Vuković-Gačić, B., Paunović, M.,& Kračun-Kolarević, M.. (2023). In situ detection of the genotoxic potential as one of the lines of evidence in the weight-of-evidence approach—the Joint Danube Survey 4 Case Study. in Mutagenesis
Oxford: Oxford University Press., 38(1), 21-32.
https://doi.org/10.1093/mutage/geac024

Jovanović Marić J, Kolarević S, Đorđević J, Sunjog K, Nikolić I, Marić A, Ilić M, Simonović P, Alygizakis N, Ng K, Oswald P, Slobodnik J, Žegura B, Vuković-Gačić B, Paunović M, Kračun-Kolarević M. In situ detection of the genotoxic potential as one of the lines of evidence in the weight-of-evidence approach—the Joint Danube Survey 4 Case Study. in Mutagenesis. 2023;38(1):21-32.
doi:10.1093/mutage/geac024 .

Jovanović Marić, Jovana, Kolarević, Stoimir, Đorđević, Jelena, Sunjog, Karolina, Nikolić, Ivan, Marić, Ana, Ilić, Marija, Simonović, Predrag, Alygizakis, Nikiforos, Ng, Kelsey, Oswald, Peter, Slobodnik, Jaroslav, Žegura, Bojana, Vuković-Gačić, Branka, Paunović, Momir, Kračun-Kolarević, Margareta, "In situ detection of the genotoxic potential as one of the lines of evidence in the weight-of-evidence approach—the Joint Danube Survey 4 Case Study" in Mutagenesis, 38, no. 1 (2023):21-32,
https://doi.org/10.1093/mutage/geac024 . .

TY  - JOUR
AU  - Lundy, Lian
AU  - Fatta-Kassinos, Despo
AU  - Slobodnik, Jaroslav
AU  - Karaolia, Popi
AU  - Cirka, Lubos
AU  - Kreuzinger, Norbert
AU  - Castiglioni, Sara
AU  - Bijlsma, Lubertus
AU  - Dulio, Valeria
AU  - Deviller, Geneviève
AU  - Lai, Foon Yin
AU  - Alygizakis, Nikiforos
AU  - Barneo, Manuela
AU  - Baz-Lomba, Jose Antonio
AU  - Béen, Frederic
AU  - Cíchová, Marianna
AU  - Conde-Pérez, Kelly
AU  - Covaci, Adrian
AU  - Donner, Erica
AU  - Ficek, Andrej
AU  - Hassard, Francis
AU  - Hedström, Annelie
AU  - Hernandez, Félix
AU  - Janská, Veronika
AU  - Jellison, Kristen
AU  - Hofman, Jan
AU  - Hill, Kelly
AU  - Hong, Pei-Ying
AU  - Kasprzyk-Hordern, Barbara
AU  - Kolarević, Stoimir
AU  - Krahulec, Jan
AU  - Lambropoulou, Dimitra
AU  - de Llanos, Rosa
AU  - Mackuľak, Tomáš
AU  - Martinez-García, Lorena
AU  - Martínez, Francisco
AU  - Medema, Gertjan
AU  - Micsinai, Adrienn
AU  - Myrmel, Mette
AU  - Nasser, Mohammed
AU  - Niederstätter, Harald
AU  - Nozal, Leonor
AU  - Oberacher, Herbert
AU  - Očenášková, Věra
AU  - Ogorzaly, Leslie
AU  - Papadopoulos, Dimitrios
AU  - Peinado, Beatriz
AU  - Pitkänen, Tarja
AU  - Poza, Margarita
AU  - Rumbo-Feal, Soraya
AU  - Sánchez, Maria Blanca
AU  - Székely, Anna J.
AU  - Soltysova, Andrea
AU  - Thomaidis, Nikolaos S.
AU  - Vallejo, Juan
AU  - van Nuijs, Alexander
AU  - Ware, Vassie
AU  - Viklander, Maria
PY  - 2021
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4246
AB  - The presence of SARS-CoV-2 RNA in wastewater was first reported in March 2020. Over the subsequent months, the potential for wastewater surveillance to contribute to COVID-19 mitigation programmes has been the focus of intense national and international research activities, gaining the attention of policy makers and the public. As a new application of an established methodology, focused collaboration between public health practitioners and wastewater researchers is essential to developing a common understanding on how, when and where the outputs of this non-invasive community-level approach can deliver actionable outcomes for public health authorities. Within this context, the NORMAN SCORE “SARS-CoV-2 in sewage” database provides a platform for rapid, open access data sharing, validated by the uploading of 276 data sets from nine countries to-date. Through offering direct access to underpinning meta-data sets (and describing its use in data interpretation), the NORMAN SCORE database is a resource for the development of recommendations on minimum data requirements for wastewater pathogen surveillance. It is also a tool to engage public health practitioners in discussions on use of the approach, providing an opportunity to build mutual understanding of the demand and supply for data and facilitate the translation of this promising research application into public health practice.
PB  - Elsevier BV
T2  - Water Research
T1  - Making Waves: Collaboration in the time of SARS-CoV-2 - rapid development of an international co-operation and wastewater surveillance database to support public health decision-making
VL  - 199
DO  - 10.1016/j.watres.2021.117167
SP  - 117167
ER  - 

@article{
author = "Lundy, Lian and Fatta-Kassinos, Despo and Slobodnik, Jaroslav and Karaolia, Popi and Cirka, Lubos and Kreuzinger, Norbert and Castiglioni, Sara and Bijlsma, Lubertus and Dulio, Valeria and Deviller, Geneviève and Lai, Foon Yin and Alygizakis, Nikiforos and Barneo, Manuela and Baz-Lomba, Jose Antonio and Béen, Frederic and Cíchová, Marianna and Conde-Pérez, Kelly and Covaci, Adrian and Donner, Erica and Ficek, Andrej and Hassard, Francis and Hedström, Annelie and Hernandez, Félix and Janská, Veronika and Jellison, Kristen and Hofman, Jan and Hill, Kelly and Hong, Pei-Ying and Kasprzyk-Hordern, Barbara and Kolarević, Stoimir and Krahulec, Jan and Lambropoulou, Dimitra and de Llanos, Rosa and Mackuľak, Tomáš and Martinez-García, Lorena and Martínez, Francisco and Medema, Gertjan and Micsinai, Adrienn and Myrmel, Mette and Nasser, Mohammed and Niederstätter, Harald and Nozal, Leonor and Oberacher, Herbert and Očenášková, Věra and Ogorzaly, Leslie and Papadopoulos, Dimitrios and Peinado, Beatriz and Pitkänen, Tarja and Poza, Margarita and Rumbo-Feal, Soraya and Sánchez, Maria Blanca and Székely, Anna J. and Soltysova, Andrea and Thomaidis, Nikolaos S. and Vallejo, Juan and van Nuijs, Alexander and Ware, Vassie and Viklander, Maria",
year = "2021",
abstract = "The presence of SARS-CoV-2 RNA in wastewater was first reported in March 2020. Over the subsequent months, the potential for wastewater surveillance to contribute to COVID-19 mitigation programmes has been the focus of intense national and international research activities, gaining the attention of policy makers and the public. As a new application of an established methodology, focused collaboration between public health practitioners and wastewater researchers is essential to developing a common understanding on how, when and where the outputs of this non-invasive community-level approach can deliver actionable outcomes for public health authorities. Within this context, the NORMAN SCORE “SARS-CoV-2 in sewage” database provides a platform for rapid, open access data sharing, validated by the uploading of 276 data sets from nine countries to-date. Through offering direct access to underpinning meta-data sets (and describing its use in data interpretation), the NORMAN SCORE database is a resource for the development of recommendations on minimum data requirements for wastewater pathogen surveillance. It is also a tool to engage public health practitioners in discussions on use of the approach, providing an opportunity to build mutual understanding of the demand and supply for data and facilitate the translation of this promising research application into public health practice.",
publisher = "Elsevier BV",
journal = "Water Research",
title = "Making Waves: Collaboration in the time of SARS-CoV-2 - rapid development of an international co-operation and wastewater surveillance database to support public health decision-making",
volume = "199",
doi = "10.1016/j.watres.2021.117167",
pages = "117167"
}

Lundy, L., Fatta-Kassinos, D., Slobodnik, J., Karaolia, P., Cirka, L., Kreuzinger, N., Castiglioni, S., Bijlsma, L., Dulio, V., Deviller, G., Lai, F. Y., Alygizakis, N., Barneo, M., Baz-Lomba, J. A., Béen, F., Cíchová, M., Conde-Pérez, K., Covaci, A., Donner, E., Ficek, A., Hassard, F., Hedström, A., Hernandez, F., Janská, V., Jellison, K., Hofman, J., Hill, K., Hong, P., Kasprzyk-Hordern, B., Kolarević, S., Krahulec, J., Lambropoulou, D., de Llanos, R., Mackuľak, T., Martinez-García, L., Martínez, F., Medema, G., Micsinai, A., Myrmel, M., Nasser, M., Niederstätter, H., Nozal, L., Oberacher, H., Očenášková, V., Ogorzaly, L., Papadopoulos, D., Peinado, B., Pitkänen, T., Poza, M., Rumbo-Feal, S., Sánchez, M. B., Székely, A. J., Soltysova, A., Thomaidis, N. S., Vallejo, J., van Nuijs, A., Ware, V.,& Viklander, M.. (2021). Making Waves: Collaboration in the time of SARS-CoV-2 - rapid development of an international co-operation and wastewater surveillance database to support public health decision-making. in Water Research
Elsevier BV., 199, 117167.
https://doi.org/10.1016/j.watres.2021.117167

Lundy L, Fatta-Kassinos D, Slobodnik J, Karaolia P, Cirka L, Kreuzinger N, Castiglioni S, Bijlsma L, Dulio V, Deviller G, Lai FY, Alygizakis N, Barneo M, Baz-Lomba JA, Béen F, Cíchová M, Conde-Pérez K, Covaci A, Donner E, Ficek A, Hassard F, Hedström A, Hernandez F, Janská V, Jellison K, Hofman J, Hill K, Hong P, Kasprzyk-Hordern B, Kolarević S, Krahulec J, Lambropoulou D, de Llanos R, Mackuľak T, Martinez-García L, Martínez F, Medema G, Micsinai A, Myrmel M, Nasser M, Niederstätter H, Nozal L, Oberacher H, Očenášková V, Ogorzaly L, Papadopoulos D, Peinado B, Pitkänen T, Poza M, Rumbo-Feal S, Sánchez MB, Székely AJ, Soltysova A, Thomaidis NS, Vallejo J, van Nuijs A, Ware V, Viklander M. Making Waves: Collaboration in the time of SARS-CoV-2 - rapid development of an international co-operation and wastewater surveillance database to support public health decision-making. in Water Research. 2021;199:117167.
doi:10.1016/j.watres.2021.117167 .

Lundy, Lian, Fatta-Kassinos, Despo, Slobodnik, Jaroslav, Karaolia, Popi, Cirka, Lubos, Kreuzinger, Norbert, Castiglioni, Sara, Bijlsma, Lubertus, Dulio, Valeria, Deviller, Geneviève, Lai, Foon Yin, Alygizakis, Nikiforos, Barneo, Manuela, Baz-Lomba, Jose Antonio, Béen, Frederic, Cíchová, Marianna, Conde-Pérez, Kelly, Covaci, Adrian, Donner, Erica, Ficek, Andrej, Hassard, Francis, Hedström, Annelie, Hernandez, Félix, Janská, Veronika, Jellison, Kristen, Hofman, Jan, Hill, Kelly, Hong, Pei-Ying, Kasprzyk-Hordern, Barbara, Kolarević, Stoimir, Krahulec, Jan, Lambropoulou, Dimitra, de Llanos, Rosa, Mackuľak, Tomáš, Martinez-García, Lorena, Martínez, Francisco, Medema, Gertjan, Micsinai, Adrienn, Myrmel, Mette, Nasser, Mohammed, Niederstätter, Harald, Nozal, Leonor, Oberacher, Herbert, Očenášková, Věra, Ogorzaly, Leslie, Papadopoulos, Dimitrios, Peinado, Beatriz, Pitkänen, Tarja, Poza, Margarita, Rumbo-Feal, Soraya, Sánchez, Maria Blanca, Székely, Anna J., Soltysova, Andrea, Thomaidis, Nikolaos S., Vallejo, Juan, van Nuijs, Alexander, Ware, Vassie, Viklander, Maria, "Making Waves: Collaboration in the time of SARS-CoV-2 - rapid development of an international co-operation and wastewater surveillance database to support public health decision-making" in Water Research, 199 (2021):117167,
https://doi.org/10.1016/j.watres.2021.117167 . .