TY  - CONF
AU  - Koller, Michael
AU  - Nürnberger, Julia
AU  - Hack, Kerstin
AU  - Dielacher, Irina
AU  - Wachter, Julian
AU  - Hoffer, Benjamin
AU  - Kohlmaier, Sophie
AU  - Hagendorfer, Christin
AU  - Kapic, Medina
AU  - Julia, Gütl
AU  - Arsenijevic, Polina
AU  - Schachner, Iris
AU  - Jakwerth, Stefan
AU  - Kolarević, Stoimir
AU  - Kračun-Kolarević, Margareta
AU  - Tóth, Erika
AU  - Savio, Domenico
AU  - Farnleitner, Andreas H.
AU  - Kittinger, Clemens
AU  - Kirschner, Alexander K.T.
AU  - Zarfel, Gernot
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6231
AB  - Human induced antibiotic resistant bacteria (ARB) are not only found in clinical surroundings: large rivers are of great concern as regards their spreading. This ongoing study´s aim is to analyse the major propagation pathways and sources of ARB in the Danube, and to compare the results with data obtained in 2013. Escherichia coli and Klebsiella spp. isolated during the 4th Joint Danube Survey were tested for their antibiotic susceptibility. 23.2% of 1635 E. coli were resistant and 11.7% were multiresistant. There was a significant increase in resistances to augmentin, moxifloxacin and piperacillin/tazobactam and a significant decrease regarding tetracycline. 23 expressed an extended-spectrum-beta-lactamase phenotype. 15.87 % of 630 Klebsiella spp. were resistant and 0.95% were multiresistant. Resistances
to moxifloxacin and augmentin were the most common resistances detected.
Two isolates showed an ESBL-phenotype, and two isolates were resistant to the last line antibiotic tigecycline. In comparison the data of 2013 and 2019 show a similar proportion for multiresistant E. coli, but regarding resistances to some single antibiotics significant changes were determined. In contrast, the Klebsiella isolates showed a very similar distribution of resistances. Despite, 30% of non-wild type resistant E. coli in the environment is a very high number when compared to clinical settings with approximately 50%. However, the relevance of these findings concerning human health and the environment is yet unclear as there is only a very limited number of studies for comparison and studies on the significance of pathways from the river back to humans are largely missing.
PB  - Belgrade: Serbian Society of Microbiology
C3  - Electronic abstract book: FEMS Conference on Microbiology in association with Serbian Society of Microbiology; 2022 Jun 30 - Jul 2; Belgrade, Serbia
T1  - Monitoring non-wild type antibiotic resistant Enterobacteriaceae in the River Danube: a six-year-comparison
SP  - 64
EP  - 65
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_6231
ER  - 

@conference{
author = "Koller, Michael and Nürnberger, Julia and Hack, Kerstin and Dielacher, Irina and Wachter, Julian and Hoffer, Benjamin and Kohlmaier, Sophie and Hagendorfer, Christin and Kapic, Medina and Julia, Gütl and Arsenijevic, Polina and Schachner, Iris and Jakwerth, Stefan and Kolarević, Stoimir and Kračun-Kolarević, Margareta and Tóth, Erika and Savio, Domenico and Farnleitner, Andreas H. and Kittinger, Clemens and Kirschner, Alexander K.T. and Zarfel, Gernot",
year = "2022",
abstract = "Human induced antibiotic resistant bacteria (ARB) are not only found in clinical surroundings: large rivers are of great concern as regards their spreading. This ongoing study´s aim is to analyse the major propagation pathways and sources of ARB in the Danube, and to compare the results with data obtained in 2013. Escherichia coli and Klebsiella spp. isolated during the 4th Joint Danube Survey were tested for their antibiotic susceptibility. 23.2% of 1635 E. coli were resistant and 11.7% were multiresistant. There was a significant increase in resistances to augmentin, moxifloxacin and piperacillin/tazobactam and a significant decrease regarding tetracycline. 23 expressed an extended-spectrum-beta-lactamase phenotype. 15.87 % of 630 Klebsiella spp. were resistant and 0.95% were multiresistant. Resistances
to moxifloxacin and augmentin were the most common resistances detected.
Two isolates showed an ESBL-phenotype, and two isolates were resistant to the last line antibiotic tigecycline. In comparison the data of 2013 and 2019 show a similar proportion for multiresistant E. coli, but regarding resistances to some single antibiotics significant changes were determined. In contrast, the Klebsiella isolates showed a very similar distribution of resistances. Despite, 30% of non-wild type resistant E. coli in the environment is a very high number when compared to clinical settings with approximately 50%. However, the relevance of these findings concerning human health and the environment is yet unclear as there is only a very limited number of studies for comparison and studies on the significance of pathways from the river back to humans are largely missing.",
publisher = "Belgrade: Serbian Society of Microbiology",
journal = "Electronic abstract book: FEMS Conference on Microbiology in association with Serbian Society of Microbiology; 2022 Jun 30 - Jul 2; Belgrade, Serbia",
title = "Monitoring non-wild type antibiotic resistant Enterobacteriaceae in the River Danube: a six-year-comparison",
pages = "64-65",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6231"
}

Koller, M., Nürnberger, J., Hack, K., Dielacher, I., Wachter, J., Hoffer, B., Kohlmaier, S., Hagendorfer, C., Kapic, M., Julia, G., Arsenijevic, P., Schachner, I., Jakwerth, S., Kolarević, S., Kračun-Kolarević, M., Tóth, E., Savio, D., Farnleitner, A. H., Kittinger, C., Kirschner, A. K.T.,& Zarfel, G.. (2022). Monitoring non-wild type antibiotic resistant Enterobacteriaceae in the River Danube: a six-year-comparison. in Electronic abstract book: FEMS Conference on Microbiology in association with Serbian Society of Microbiology; 2022 Jun 30 - Jul 2; Belgrade, Serbia
Belgrade: Serbian Society of Microbiology., 64-65.
https://hdl.handle.net/21.15107/rcub_ibiss_6231

Koller M, Nürnberger J, Hack K, Dielacher I, Wachter J, Hoffer B, Kohlmaier S, Hagendorfer C, Kapic M, Julia G, Arsenijevic P, Schachner I, Jakwerth S, Kolarević S, Kračun-Kolarević M, Tóth E, Savio D, Farnleitner AH, Kittinger C, Kirschner AK, Zarfel G. Monitoring non-wild type antibiotic resistant Enterobacteriaceae in the River Danube: a six-year-comparison. in Electronic abstract book: FEMS Conference on Microbiology in association with Serbian Society of Microbiology; 2022 Jun 30 - Jul 2; Belgrade, Serbia. 2022;:64-65.
https://hdl.handle.net/21.15107/rcub_ibiss_6231 .

Koller, Michael, Nürnberger, Julia, Hack, Kerstin, Dielacher, Irina, Wachter, Julian, Hoffer, Benjamin, Kohlmaier, Sophie, Hagendorfer, Christin, Kapic, Medina, Julia, Gütl, Arsenijevic, Polina, Schachner, Iris, Jakwerth, Stefan, Kolarević, Stoimir, Kračun-Kolarević, Margareta, Tóth, Erika, Savio, Domenico, Farnleitner, Andreas H., Kittinger, Clemens, Kirschner, Alexander K.T., Zarfel, Gernot, "Monitoring non-wild type antibiotic resistant Enterobacteriaceae in the River Danube: a six-year-comparison" in Electronic abstract book: FEMS Conference on Microbiology in association with Serbian Society of Microbiology; 2022 Jun 30 - Jul 2; Belgrade, Serbia (2022):64-65,
https://hdl.handle.net/21.15107/rcub_ibiss_6231 .