TY  - JOUR
AU  - Mimica-Dukić, Neda M
AU  - Bozin, Biljana N
AU  - Soković, Marina
AU  - Simin, Natasa D
PY  - 2004
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1734
AB  - The present study describes antimicrobial and free radical scavenging capacity (RSC) together with the effects on lipid peroxidation (LP) of Melissa officinalis essential oil. The chemical profile of essential oil was evaluated by the means of gas chromatography-mass spectrometry (GC-MS) and thin-layer chromatography (TLC). RSC was assessed measuring the scavenging activity of essential oil on the 2,2-diphenyl-1-picrylhydrazyl (DPPH.) and OH. radicals. The effect on LP was evaluated following the activities on Fe2+/ascorbate and Fe2+/H2O2 systems of induction, The antimicrobial activity was tested against 13 bacterial strains and six fungi. The examined essential oil exhibited very strong RSC, reducing the DPPH radical formation (IC50 = 7.58 mug/mL) and OH radical generation (IC50 = 1.74 mug/mL) in a dose-dependent manner. According to the GC-MS and TLC (dot-blot techniques), the most powerful scavenging compounds were monoterpene aldehydes and ketones (neral/geranial, citronellal, isomenthone, and menthone) and mono- and sesquiterpene hydrocarbons (E-caryophyllene). Very strong inhibition of LP, particularly in the Fe2+/H2O2 system of induction (94.59% for 2.13 mug/mL), was observed in both cases, also in a dose-dependent manner. The most effective antibacterial activity was expressed on a multiresistant strain of Shigella sonei. A significant rate of antifungal activity was exhibited on Trichophyton species.
T2  - Journal of Agricultural and Food Chemistry
T1  - Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil
IS  - 9
VL  - 52
EP  - 2489
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1734
ER  - 

@article{
author = "Mimica-Dukić, Neda M and Bozin, Biljana N and Soković, Marina and Simin, Natasa D",
year = "2004",
abstract = "The present study describes antimicrobial and free radical scavenging capacity (RSC) together with the effects on lipid peroxidation (LP) of Melissa officinalis essential oil. The chemical profile of essential oil was evaluated by the means of gas chromatography-mass spectrometry (GC-MS) and thin-layer chromatography (TLC). RSC was assessed measuring the scavenging activity of essential oil on the 2,2-diphenyl-1-picrylhydrazyl (DPPH.) and OH. radicals. The effect on LP was evaluated following the activities on Fe2+/ascorbate and Fe2+/H2O2 systems of induction, The antimicrobial activity was tested against 13 bacterial strains and six fungi. The examined essential oil exhibited very strong RSC, reducing the DPPH radical formation (IC50 = 7.58 mug/mL) and OH radical generation (IC50 = 1.74 mug/mL) in a dose-dependent manner. According to the GC-MS and TLC (dot-blot techniques), the most powerful scavenging compounds were monoterpene aldehydes and ketones (neral/geranial, citronellal, isomenthone, and menthone) and mono- and sesquiterpene hydrocarbons (E-caryophyllene). Very strong inhibition of LP, particularly in the Fe2+/H2O2 system of induction (94.59% for 2.13 mug/mL), was observed in both cases, also in a dose-dependent manner. The most effective antibacterial activity was expressed on a multiresistant strain of Shigella sonei. A significant rate of antifungal activity was exhibited on Trichophyton species.",
journal = "Journal of Agricultural and Food Chemistry",
title = "Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil",
number = "9",
volume = "52",
pages = "2489",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1734"
}

Mimica-Dukić, N. M., Bozin, B. N., Soković, M.,& Simin, N. D.. (2004). Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil. in Journal of Agricultural and Food Chemistry, 52(9).
https://hdl.handle.net/21.15107/rcub_ibiss_1734

Mimica-Dukić NM, Bozin BN, Soković M, Simin ND. Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil. in Journal of Agricultural and Food Chemistry. 2004;52(9):null-2489.
https://hdl.handle.net/21.15107/rcub_ibiss_1734 .

Mimica-Dukić, Neda M, Bozin, Biljana N, Soković, Marina, Simin, Natasa D, "Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil" in Journal of Agricultural and Food Chemistry, 52, no. 9 (2004),
https://hdl.handle.net/21.15107/rcub_ibiss_1734 .

TY  - JOUR
AU  - Mimica-Dukić, Neda M
AU  - Bozin, Biljana N
AU  - Soković, Marina
AU  - Mihajlović, B
AU  - Matavulj, Milan N
PY  - 2003
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1767
AB  - The present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oils from Mentha aquatica L., Mentha longifolia L., and Mentha piperita L. The chemical profile of each essential oil was determined by GC-MS and TLC. All essential oils exhibited very strong antibacterial activity, in particularly against Esherichia coli strains. The most powerful was M. piperita essential oil, especially towards multiresistant strain of Shigella sonei and Micrococcus flavus ATTC 10240. All tested oils showed significant fungistatic and fungicidal activity [expressed as minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values, respectively], that were considerably higher than those of the commercial fungicide bifonazole. The essential oils of M. piperita and M. longifolia were found to be more active than the essential oil of M. aquatica. Especially low MIC (4 muL/mL) and MFC (4 muL/mL) were found with M. piperita oil against Trichophyton tonsurans and Candida albicans (both 8 muL/mL). The RSC was evaluated by measuring the scavenging activity of the essential oils on the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and OH radicals. All examined essential oils were able to reduce DPPH radicals into the neutral DPPH-H form, and this activity was dose-dependent. However, only the M. piperita oil reduced DPPH to 50% (IC50 = 2.53 mug/mL). The M. piperita essential oil also exhibited the highest OH radical scavenging activity, reducing OH radical generation in the Fenton reaction by 24% (pure oil). According to GC-MS and TLC (dot-blot techniques), the most powerful scavenging compounds were monoterpene ketones (menthone and isomenthone) in the essential oils of M. longifolia and M. piperita and 1,8-cineole in the oil of M. aquatica.
T2  - Planta Medica
T1  - Antimicrobial and antioxidant activities of three Mentha species essential oils
IS  - 5
VL  - 69
DO  - 10.1055/s-2003-39704
EP  - 419
ER  - 

@article{
author = "Mimica-Dukić, Neda M and Bozin, Biljana N and Soković, Marina and Mihajlović, B and Matavulj, Milan N",
year = "2003",
abstract = "The present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oils from Mentha aquatica L., Mentha longifolia L., and Mentha piperita L. The chemical profile of each essential oil was determined by GC-MS and TLC. All essential oils exhibited very strong antibacterial activity, in particularly against Esherichia coli strains. The most powerful was M. piperita essential oil, especially towards multiresistant strain of Shigella sonei and Micrococcus flavus ATTC 10240. All tested oils showed significant fungistatic and fungicidal activity [expressed as minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values, respectively], that were considerably higher than those of the commercial fungicide bifonazole. The essential oils of M. piperita and M. longifolia were found to be more active than the essential oil of M. aquatica. Especially low MIC (4 muL/mL) and MFC (4 muL/mL) were found with M. piperita oil against Trichophyton tonsurans and Candida albicans (both 8 muL/mL). The RSC was evaluated by measuring the scavenging activity of the essential oils on the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and OH radicals. All examined essential oils were able to reduce DPPH radicals into the neutral DPPH-H form, and this activity was dose-dependent. However, only the M. piperita oil reduced DPPH to 50% (IC50 = 2.53 mug/mL). The M. piperita essential oil also exhibited the highest OH radical scavenging activity, reducing OH radical generation in the Fenton reaction by 24% (pure oil). According to GC-MS and TLC (dot-blot techniques), the most powerful scavenging compounds were monoterpene ketones (menthone and isomenthone) in the essential oils of M. longifolia and M. piperita and 1,8-cineole in the oil of M. aquatica.",
journal = "Planta Medica",
title = "Antimicrobial and antioxidant activities of three Mentha species essential oils",
number = "5",
volume = "69",
doi = "10.1055/s-2003-39704",
pages = "419"
}

Mimica-Dukić, N. M., Bozin, B. N., Soković, M., Mihajlović, B.,& Matavulj, M. N.. (2003). Antimicrobial and antioxidant activities of three Mentha species essential oils. in Planta Medica, 69(5).
https://doi.org/10.1055/s-2003-39704

Mimica-Dukić NM, Bozin BN, Soković M, Mihajlović B, Matavulj MN. Antimicrobial and antioxidant activities of three Mentha species essential oils. in Planta Medica. 2003;69(5):null-419.
doi:10.1055/s-2003-39704 .

Mimica-Dukić, Neda M, Bozin, Biljana N, Soković, Marina, Mihajlović, B, Matavulj, Milan N, "Antimicrobial and antioxidant activities of three Mentha species essential oils" in Planta Medica, 69, no. 5 (2003),
https://doi.org/10.1055/s-2003-39704 . .