TY  - JOUR
AU  - Vorobyov, Vasily
AU  - Petković, Branka
AU  - Pešić, Vesna
AU  - Prolić, Zlatko
PY  - 2010
UR  - https://www.tandfonline.com/doi/full/10.3109/09553000903567938
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3796
AB  - Purpose: To compare the effects of repeated exposure to extremely low frequency-modulated microwaves (ELF-MW) on cortical and hypothalamic electroencephalograms (EEG). Materials and methods: In 10 freely moving rats with carbon electrodes implanted into the cortex and dorsomedial hypothalamus, averaged frequency spectra (0.5-30 Hz) of the EEG were studied for five consecutive days either under sham exposures (five rats) or under mixed sham/MW-exposures (five rats). The rats were exposed to ELF-MW (915 MHz, 20-ms pulse duration, approximately 0.3 mW/cm(2), 4 Hz) intermittently (1-min 'On', 1-min 'Off') for 10 min (specific absorption rate, SAR, approximately 0.7 mW/g on average) several times per day, with 10-min pre- and post-exposure periods. Results: In baseline EEG, the activities of 3.2-6.0 Hz and 17.8-30.5 Hz dominated in the cortex and of 6.0-17.8 Hz in the hypothalamus. This cortical-hypothalamic imbalance was relatively stable at sham-exposures and insensitive to ELF-MW in all frequency ranges but one. ELF-MW increased the beta(2) (17.8-30.5 Hz) level in the hypothalamus to a greater extent than in the cortex, causing significant diminishing of the initial EEG bias between them. Moreover, a cumulative phenomenon under repeated exposures to ELF-MW was revealed. Conclusions: These results are in line with evidence that repeated low-level exposure to ELF-MW affects brain functioning and provide an additional approach when analysing underlying mechanisms.
PB  - Informa Healthcare
T2  - International Journal of Radiation Biology
T1  - Repeated exposure to low-level extremely low frequency-modulated microwaves affects cortex-hypothalamus interplay in freely moving rats: EEG study
IS  - 5
VL  - 86
DO  - 10.3109/09553000903567938
SP  - 376
EP  - 383
ER  - 

@article{
author = "Vorobyov, Vasily and Petković, Branka and Pešić, Vesna and Prolić, Zlatko",
year = "2010",
abstract = "Purpose: To compare the effects of repeated exposure to extremely low frequency-modulated microwaves (ELF-MW) on cortical and hypothalamic electroencephalograms (EEG). Materials and methods: In 10 freely moving rats with carbon electrodes implanted into the cortex and dorsomedial hypothalamus, averaged frequency spectra (0.5-30 Hz) of the EEG were studied for five consecutive days either under sham exposures (five rats) or under mixed sham/MW-exposures (five rats). The rats were exposed to ELF-MW (915 MHz, 20-ms pulse duration, approximately 0.3 mW/cm(2), 4 Hz) intermittently (1-min 'On', 1-min 'Off') for 10 min (specific absorption rate, SAR, approximately 0.7 mW/g on average) several times per day, with 10-min pre- and post-exposure periods. Results: In baseline EEG, the activities of 3.2-6.0 Hz and 17.8-30.5 Hz dominated in the cortex and of 6.0-17.8 Hz in the hypothalamus. This cortical-hypothalamic imbalance was relatively stable at sham-exposures and insensitive to ELF-MW in all frequency ranges but one. ELF-MW increased the beta(2) (17.8-30.5 Hz) level in the hypothalamus to a greater extent than in the cortex, causing significant diminishing of the initial EEG bias between them. Moreover, a cumulative phenomenon under repeated exposures to ELF-MW was revealed. Conclusions: These results are in line with evidence that repeated low-level exposure to ELF-MW affects brain functioning and provide an additional approach when analysing underlying mechanisms.",
publisher = "Informa Healthcare",
journal = "International Journal of Radiation Biology",
title = "Repeated exposure to low-level extremely low frequency-modulated microwaves affects cortex-hypothalamus interplay in freely moving rats: EEG study",
number = "5",
volume = "86",
doi = "10.3109/09553000903567938",
pages = "376-383"
}

Vorobyov, V., Petković, B., Pešić, V.,& Prolić, Z.. (2010). Repeated exposure to low-level extremely low frequency-modulated microwaves affects cortex-hypothalamus interplay in freely moving rats: EEG study. in International Journal of Radiation Biology
Informa Healthcare., 86(5), 376-383.
https://doi.org/10.3109/09553000903567938

Vorobyov V, Petković B, Pešić V, Prolić Z. Repeated exposure to low-level extremely low frequency-modulated microwaves affects cortex-hypothalamus interplay in freely moving rats: EEG study. in International Journal of Radiation Biology. 2010;86(5):376-383.
doi:10.3109/09553000903567938 .

Vorobyov, Vasily, Petković, Branka, Pešić, Vesna, Prolić, Zlatko, "Repeated exposure to low-level extremely low frequency-modulated microwaves affects cortex-hypothalamus interplay in freely moving rats: EEG study" in International Journal of Radiation Biology, 86, no. 5 (2010):376-383,
https://doi.org/10.3109/09553000903567938 . .

TY  - JOUR
AU  - Petković, Branka
AU  - Pešić, Vesna
AU  - Jelenković, Ankica
AU  - Vorobyov, Vasily
AU  - Prolić, Zlatko
PY  - 2005
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0361923005003011?via%3Dihub
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3807
AB  - The effects of chronic (7 days) exposure to an extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) on spontaneous and amphetamine-induced (1.5 mg/kg, i.p.) locomotor and stereotypic activities in adult rats were examined by open field test for 2 h on exposure days 1, 3, and 7. After 1 day of exposure to ELF-MF, the spontaneous locomotor activity was increased clearly at the first hour of observation and significantly at the second one as compared to the corresponding values in other series with ELF-MF and sham-exposed animals. After 7 days of exposure to ELF-MF, an amphetamine enhancing effect on the locomotor activity was significantly reduced at the second hour of observation as compared to that in 1-day- and sham-exposed rats treated with amphetamine. In contrast to the locomotor activity, the amphetamine-induced stereotypic behaviour in 7-day pre-exposed rats was significantly reduced at the first hour versus sham-exposed rats. While at the second hour of observation this effect was significant as compared to 1- and 3-day exposed animals (but not sham-exposed rats). Our results indicate that an extremely low frequency magnetic field is able to affect differently two types of behaviour, which are dependent on both the time course of exposure and the imbalance in the brain mediatory systems.
PB  - Pergamon-Elsevier Science Ltd
T2  - Brain Research Bulletin
T1  - Different effects of chronic exposure to ELF magnetic field on spontaneous and amphetamine-induced locomotor and stereotypic activities in rats
IS  - 6
VL  - 67
DO  - 10.1016/j.brainresbull.2005.07.017
SP  - 498
EP  - 503
ER  - 

@article{
author = "Petković, Branka and Pešić, Vesna and Jelenković, Ankica and Vorobyov, Vasily and Prolić, Zlatko",
year = "2005",
abstract = "The effects of chronic (7 days) exposure to an extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) on spontaneous and amphetamine-induced (1.5 mg/kg, i.p.) locomotor and stereotypic activities in adult rats were examined by open field test for 2 h on exposure days 1, 3, and 7. After 1 day of exposure to ELF-MF, the spontaneous locomotor activity was increased clearly at the first hour of observation and significantly at the second one as compared to the corresponding values in other series with ELF-MF and sham-exposed animals. After 7 days of exposure to ELF-MF, an amphetamine enhancing effect on the locomotor activity was significantly reduced at the second hour of observation as compared to that in 1-day- and sham-exposed rats treated with amphetamine. In contrast to the locomotor activity, the amphetamine-induced stereotypic behaviour in 7-day pre-exposed rats was significantly reduced at the first hour versus sham-exposed rats. While at the second hour of observation this effect was significant as compared to 1- and 3-day exposed animals (but not sham-exposed rats). Our results indicate that an extremely low frequency magnetic field is able to affect differently two types of behaviour, which are dependent on both the time course of exposure and the imbalance in the brain mediatory systems.",
publisher = "Pergamon-Elsevier Science Ltd",
journal = "Brain Research Bulletin",
title = "Different effects of chronic exposure to ELF magnetic field on spontaneous and amphetamine-induced locomotor and stereotypic activities in rats",
number = "6",
volume = "67",
doi = "10.1016/j.brainresbull.2005.07.017",
pages = "498-503"
}

Petković, B., Pešić, V., Jelenković, A., Vorobyov, V.,& Prolić, Z.. (2005). Different effects of chronic exposure to ELF magnetic field on spontaneous and amphetamine-induced locomotor and stereotypic activities in rats. in Brain Research Bulletin
Pergamon-Elsevier Science Ltd., 67(6), 498-503.
https://doi.org/10.1016/j.brainresbull.2005.07.017

Petković B, Pešić V, Jelenković A, Vorobyov V, Prolić Z. Different effects of chronic exposure to ELF magnetic field on spontaneous and amphetamine-induced locomotor and stereotypic activities in rats. in Brain Research Bulletin. 2005;67(6):498-503.
doi:10.1016/j.brainresbull.2005.07.017 .

Petković, Branka, Pešić, Vesna, Jelenković, Ankica, Vorobyov, Vasily, Prolić, Zlatko, "Different effects of chronic exposure to ELF magnetic field on spontaneous and amphetamine-induced locomotor and stereotypic activities in rats" in Brain Research Bulletin, 67, no. 6 (2005):498-503,
https://doi.org/10.1016/j.brainresbull.2005.07.017 . .

TY  - JOUR
AU  - Pešić, Vesna
AU  - Petković, Branka
AU  - Jelenković, Ankica
AU  - Vorobyov, Vasily
AU  - Prolić, Zlatko
PY  - 2004
UR  - https://www.sciencedirect.com/science/article/pii/S016643280300281X?via%3Dihub
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3810
AB  - The effects of short-term (15 min) pre-exposure of rats to extremely low-frequency magnetic field (ELF-MF, 50 Hz, 6 mT) on their motor (locomotor and stereotypic) activity induced by D-amphetamine sulphate (AMPH) at different doses (0.5, 1.5 and 4.5 mg/kg, i.p.) were studied in the open field test. In saline-treated rats both parameters of motor activity were unaffected by ELF-MF irradiation. The rats pre-exposed to ELF-MF and injected with the lowest dose of AMPH showed the same locomotor activity as control animals, while their stereotypic behaviour was significantly elevated. ELF-MF in combination with AMPH at higher doses significantly enhanced motor activity when compared with values obtained in both control and combined experiments with the lowest dose of the drug. However, only combined locomotor effect at the middle dose of AMPH was significantly greater than those observed in corresponding experiments with AMPH alone. These results demonstrate that acute short-term exposure to ELF-MF is able to modify a motor activity in dependence on the extent of AMPH-induced neurotransmitter imbalance.
PB  - Elsevier
T2  - Behavioural Brain Research
T1  - Non-linearity in combined effects of ELF magnetic field and amphetamine on motor activity in rats
IS  - 1-2
VL  - 150
DO  - 10.1016/j.bbr.2003.07.003
SP  - 223
EP  - 227
ER  - 

@article{
author = "Pešić, Vesna and Petković, Branka and Jelenković, Ankica and Vorobyov, Vasily and Prolić, Zlatko",
year = "2004",
abstract = "The effects of short-term (15 min) pre-exposure of rats to extremely low-frequency magnetic field (ELF-MF, 50 Hz, 6 mT) on their motor (locomotor and stereotypic) activity induced by D-amphetamine sulphate (AMPH) at different doses (0.5, 1.5 and 4.5 mg/kg, i.p.) were studied in the open field test. In saline-treated rats both parameters of motor activity were unaffected by ELF-MF irradiation. The rats pre-exposed to ELF-MF and injected with the lowest dose of AMPH showed the same locomotor activity as control animals, while their stereotypic behaviour was significantly elevated. ELF-MF in combination with AMPH at higher doses significantly enhanced motor activity when compared with values obtained in both control and combined experiments with the lowest dose of the drug. However, only combined locomotor effect at the middle dose of AMPH was significantly greater than those observed in corresponding experiments with AMPH alone. These results demonstrate that acute short-term exposure to ELF-MF is able to modify a motor activity in dependence on the extent of AMPH-induced neurotransmitter imbalance.",
publisher = "Elsevier",
journal = "Behavioural Brain Research",
title = "Non-linearity in combined effects of ELF magnetic field and amphetamine on motor activity in rats",
number = "1-2",
volume = "150",
doi = "10.1016/j.bbr.2003.07.003",
pages = "223-227"
}

Pešić, V., Petković, B., Jelenković, A., Vorobyov, V.,& Prolić, Z.. (2004). Non-linearity in combined effects of ELF magnetic field and amphetamine on motor activity in rats. in Behavioural Brain Research
Elsevier., 150(1-2), 223-227.
https://doi.org/10.1016/j.bbr.2003.07.003

Pešić V, Petković B, Jelenković A, Vorobyov V, Prolić Z. Non-linearity in combined effects of ELF magnetic field and amphetamine on motor activity in rats. in Behavioural Brain Research. 2004;150(1-2):223-227.
doi:10.1016/j.bbr.2003.07.003 .

Pešić, Vesna, Petković, Branka, Jelenković, Ankica, Vorobyov, Vasily, Prolić, Zlatko, "Non-linearity in combined effects of ELF magnetic field and amphetamine on motor activity in rats" in Behavioural Brain Research, 150, no. 1-2 (2004):223-227,
https://doi.org/10.1016/j.bbr.2003.07.003 . .

TY  - JOUR
AU  - Vorobyov, Vasily
AU  - Pešić, Vesna
AU  - Petković, Branka
AU  - Prolić, Zlatko
PY  - 2004
UR  - https://www.tandfonline.com/doi/abs/10.1080/09553000400007672
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3806
AB  - Purpose: To compare in the electroencephalogram of rats the effects of scopolamine (an acetylcholine receptor antagonist) alone and after repeated exposure to low‐level microwaves modulated at extremely low frequency. Materials and methods: Averaged frequency spectra (0.5–30 Hz) of the electroencephalogram were studied in freely moving rats with carbon electrodes implanted into the somatosensory cortex. The rats were repeatedly (3 days, 30 min day−1) exposed to low‐intensity
(≅0.3 mW cm−2) microwaves (915 MHz, 20‐ms pulse duration), amplitude modulated (square‐wave) at extremely low frequency (4 Hz). Results: The exposure to extremely low frequency microwaves alone significantly enhanced the fast electroencephalographic rhythms (18–30 Hz). This effect was observed neither in subsequent sham‐exposure experiment nor in radiation‐naïve animals. In the microwave‐exposed rats, scopolamine
(0.1 mg kg−1, subcutaneously) did not cause a slowing in the electroencephalogram that was shown in non‐exposed rats. A similarity between the scopolamine‐induced electroencephalogram effect in the microwave‐exposed rats and that of physostigmine (enhancing the acetylcholine level in the brain) in radiation‐naïve animals was noted. 
This paradoxical phenomenon stimulates new experimentation for understanding its mechanism(s). Conclusions: The data obtained provide additional evidence that repeated low‐level exposure to extremely low frequency microwaves can modify an activity of cholinergic system in the brain.
PB  - Taylor & Francis Ltd
T2  - International Journal of Radiation Biology
T1  - Repeated exposure to low-level extremely low frequency-modulated microwaves affects baseline and scopolamine-modified electroencephalograms in freely moving rats
IS  - 9
VL  - 80
DO  - 10.1080/09553000400007672
SP  - 691
EP  - 698
ER  - 

@article{
author = "Vorobyov, Vasily and Pešić, Vesna and Petković, Branka and Prolić, Zlatko",
year = "2004",
abstract = "Purpose: To compare in the electroencephalogram of rats the effects of scopolamine (an acetylcholine receptor antagonist) alone and after repeated exposure to low‐level microwaves modulated at extremely low frequency. Materials and methods: Averaged frequency spectra (0.5–30 Hz) of the electroencephalogram were studied in freely moving rats with carbon electrodes implanted into the somatosensory cortex. The rats were repeatedly (3 days, 30 min day−1) exposed to low‐intensity
(≅0.3 mW cm−2) microwaves (915 MHz, 20‐ms pulse duration), amplitude modulated (square‐wave) at extremely low frequency (4 Hz). Results: The exposure to extremely low frequency microwaves alone significantly enhanced the fast electroencephalographic rhythms (18–30 Hz). This effect was observed neither in subsequent sham‐exposure experiment nor in radiation‐naïve animals. In the microwave‐exposed rats, scopolamine
(0.1 mg kg−1, subcutaneously) did not cause a slowing in the electroencephalogram that was shown in non‐exposed rats. A similarity between the scopolamine‐induced electroencephalogram effect in the microwave‐exposed rats and that of physostigmine (enhancing the acetylcholine level in the brain) in radiation‐naïve animals was noted. 
This paradoxical phenomenon stimulates new experimentation for understanding its mechanism(s). Conclusions: The data obtained provide additional evidence that repeated low‐level exposure to extremely low frequency microwaves can modify an activity of cholinergic system in the brain.",
publisher = "Taylor & Francis Ltd",
journal = "International Journal of Radiation Biology",
title = "Repeated exposure to low-level extremely low frequency-modulated microwaves affects baseline and scopolamine-modified electroencephalograms in freely moving rats",
number = "9",
volume = "80",
doi = "10.1080/09553000400007672",
pages = "691-698"
}

Vorobyov, V., Pešić, V., Petković, B.,& Prolić, Z.. (2004). Repeated exposure to low-level extremely low frequency-modulated microwaves affects baseline and scopolamine-modified electroencephalograms in freely moving rats. in International Journal of Radiation Biology
Taylor & Francis Ltd., 80(9), 691-698.
https://doi.org/10.1080/09553000400007672

Vorobyov V, Pešić V, Petković B, Prolić Z. Repeated exposure to low-level extremely low frequency-modulated microwaves affects baseline and scopolamine-modified electroencephalograms in freely moving rats. in International Journal of Radiation Biology. 2004;80(9):691-698.
doi:10.1080/09553000400007672 .

Vorobyov, Vasily, Pešić, Vesna, Petković, Branka, Prolić, Zlatko, "Repeated exposure to low-level extremely low frequency-modulated microwaves affects baseline and scopolamine-modified electroencephalograms in freely moving rats" in International Journal of Radiation Biology, 80, no. 9 (2004):691-698,
https://doi.org/10.1080/09553000400007672 . .