@article{
author = "Milic, Sonja and Pristov, Jelena Bogdanovic and Mutavdzic, Dragosav and Savic, Aleksandar and Spasić, Mihajlo and Spasojevic, Ivan",
year = "2015",
abstract = "Herein we compared antioxidative activities (AA) of 25 free L-amino
acids (FAA) against Fenton system-mediated hydroxyl radical (HO center
dot) production in aqueous solution, and examined the relation between
AA and a set of physicochemical properties. The tank order according -to
AA was: Tip > notleucine > Phe, Lett > Ile > His
>3,4-dihydrOxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydtoxyproline
> alpha-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp.
Sulfur-containing FAA generated different secondary reactive products,
which were discriminated by the means of electron paramagnetic resonance
spin-trapping spectroscopy. AA showed a general positive correlation
with hydrophobicity. However, when taken separately, uncharged FAA
exhibited strong positive correlation of AA with hydrophobicity whereas
charged FAA showed negative or no significant correlation depending on
the scale applied. A general strong negative correlation was found
between AA and polarity. Steric parameters and hydration numbers
correlated positively with AA of rtoripolar side-chain FAA. In addition)
a decrease of temperature which promotes hydrophobic hydration resulted
in increased AA. This implies that HO-provoked oxidation of FAA is
strongly affected by hydrophobic hydration. Our findings are important
for the understanding of oxidation processes in natural and waste
waters.",
journal = "Environmental Science & Technology",
title = "The Relationship of Physicochemical Properties to the Antioxidative
Activity of Free Amino Acids in Fenton System",
number = "7",
volume = "49",
doi = "10.1021/es5053396",
pages = "4245-4254"
}