TY  - CONF
AU  - Đorđević, Ana
AU  - Vujković Cvijin, Ivan I.
AU  - Lešović, Snežana J.
AU  - Gligorovska, Ljupka
AU  - Bursać, Biljana
AU  - Vojnović-Milutinović, Danijela
AU  - Matić, Gordana
PY  - 2019
UR  - https://blog.u-bourgogne.fr/cost-nutredox/wp-content/uploads/sites/81/2019/09/20191002-Lisbon-Abstract-book-vf-min.pdf
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3994
AB  - Prevalence  of  obesity  among  adolescents  has  been  constantly  increasing  in  the  last decades. The  treatment  of  obesity  requires  multidisciplinary  approach,  which  includes dietary management. However, not all people respond to dietary intervention in the same way. Since gut microbiota has been tightly linked to obesity, the aim of this pilot study was to assess whether microbiota composition affects the outcome of the hypocaloric diet on weight loss in obese male adolescents.Forty-four obese male adolescents(average BMI>95thpercentile), 12-15 years old, were selected  from  the  large  cohort  of  500  patients.  Their  body  composition  was  assessed before  and  after  3-week  balanced  hypocaloric  diet  (1200-1700  kcal)  with  preserved nutritional  value.    Microbial  DNA  was  extracted  from  cryopreserved  fecal  samples collected before the dietary intervention. Alterations of the gut microbiota were analyzed using MiSeq 16S rRNA gene sequencing. The primary outcome of the diet was the change in body weight and BMI. Subjects were divided  in  2  groups  according  to  significant  differences  in  delta  BMI  after  the  dietary intervention (P< 0.001). The values for delta BMIs were 1.93 and 2.66 for groups 1 and 2,  respectively.  The  observed  differences  were  associated  with  fecal  microbiome composition.  Group  2  subjects,  which  have  lost  more  weight,  originally  had  less Firmicutes   spp. bacteria,   more   specifically   from   families Lachnospiraceae and Desulfovibrionaceae. These  preliminary  results  show  that  the  ability  for  diet-induced  weight  loss  could  be associated   with   microbiota   composition.   Whether   certain   bacterial   taxa   represent facilitating or  resilience  factor  for  weight  loss  is  yet  to  be  determined  in  future experiments.
PB  - COST (European Cooperation in Science and Technology), NutRedox COST Action CA 16112
PB  - Universidade Lusófona
C3  - Lisbon, Portugal: NutRedox COST (European Cooperation in Science and Technology) Action CA 16112 Abstract Book
T1  - Gut Microbiota Composition Influences the Extent of Weight Loss After Hypocaloric Diet in Obese Male Adolescents
SP  - 36
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_3994
ER  - 

@conference{
author = "Đorđević, Ana and Vujković Cvijin, Ivan I. and Lešović, Snežana J. and Gligorovska, Ljupka and Bursać, Biljana and Vojnović-Milutinović, Danijela and Matić, Gordana",
year = "2019",
abstract = "Prevalence  of  obesity  among  adolescents  has  been  constantly  increasing  in  the  last decades. The  treatment  of  obesity  requires  multidisciplinary  approach,  which  includes dietary management. However, not all people respond to dietary intervention in the same way. Since gut microbiota has been tightly linked to obesity, the aim of this pilot study was to assess whether microbiota composition affects the outcome of the hypocaloric diet on weight loss in obese male adolescents.Forty-four obese male adolescents(average BMI>95thpercentile), 12-15 years old, were selected  from  the  large  cohort  of  500  patients.  Their  body  composition  was  assessed before  and  after  3-week  balanced  hypocaloric  diet  (1200-1700  kcal)  with  preserved nutritional  value.    Microbial  DNA  was  extracted  from  cryopreserved  fecal  samples collected before the dietary intervention. Alterations of the gut microbiota were analyzed using MiSeq 16S rRNA gene sequencing. The primary outcome of the diet was the change in body weight and BMI. Subjects were divided  in  2  groups  according  to  significant  differences  in  delta  BMI  after  the  dietary intervention (P< 0.001). The values for delta BMIs were 1.93 and 2.66 for groups 1 and 2,  respectively.  The  observed  differences  were  associated  with  fecal  microbiome composition.  Group  2  subjects,  which  have  lost  more  weight,  originally  had  less Firmicutes   spp. bacteria,   more   specifically   from   families Lachnospiraceae and Desulfovibrionaceae. These  preliminary  results  show  that  the  ability  for  diet-induced  weight  loss  could  be associated   with   microbiota   composition.   Whether   certain   bacterial   taxa   represent facilitating or  resilience  factor  for  weight  loss  is  yet  to  be  determined  in  future experiments.",
publisher = "COST (European Cooperation in Science and Technology), NutRedox COST Action CA 16112, Universidade Lusófona",
journal = "Lisbon, Portugal: NutRedox COST (European Cooperation in Science and Technology) Action CA 16112 Abstract Book",
title = "Gut Microbiota Composition Influences the Extent of Weight Loss After Hypocaloric Diet in Obese Male Adolescents",
pages = "36",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_3994"
}

Đorđević, A., Vujković Cvijin, I. I., Lešović, S. J., Gligorovska, L., Bursać, B., Vojnović-Milutinović, D.,& Matić, G.. (2019). Gut Microbiota Composition Influences the Extent of Weight Loss After Hypocaloric Diet in Obese Male Adolescents. in Lisbon, Portugal: NutRedox COST (European Cooperation in Science and Technology) Action CA 16112 Abstract Book
COST (European Cooperation in Science and Technology), NutRedox COST Action CA 16112., 36.
https://hdl.handle.net/21.15107/rcub_ibiss_3994

Đorđević A, Vujković Cvijin II, Lešović SJ, Gligorovska L, Bursać B, Vojnović-Milutinović D, Matić G. Gut Microbiota Composition Influences the Extent of Weight Loss After Hypocaloric Diet in Obese Male Adolescents. in Lisbon, Portugal: NutRedox COST (European Cooperation in Science and Technology) Action CA 16112 Abstract Book. 2019;:36.
https://hdl.handle.net/21.15107/rcub_ibiss_3994 .

Đorđević, Ana, Vujković Cvijin, Ivan I., Lešović, Snežana J., Gligorovska, Ljupka, Bursać, Biljana, Vojnović-Milutinović, Danijela, Matić, Gordana, "Gut Microbiota Composition Influences the Extent of Weight Loss After Hypocaloric Diet in Obese Male Adolescents" in Lisbon, Portugal: NutRedox COST (European Cooperation in Science and Technology) Action CA 16112 Abstract Book (2019):36,
https://hdl.handle.net/21.15107/rcub_ibiss_3994 .