TY  - JOUR
AU  - Mitrović, Marko
AU  - Tatalović, Nikola
AU  - Nikolić-Kokić, Aleksandra
AU  - Ciraj-Bjelac, Olivera
AU  - Krstić, Nikola
AU  - Oreščanin Dušić, Zorana
AU  - Krstić, Dragana
AU  - Jovanović, Zoran
AU  - Blagojević, Duško
AU  - Lazarević-Macanović, Mirjana
PY  - 2018
UR  - http://www.doiserbia.nb.rs/Article.aspx?ID=0354-46641800029M
UR  - http://www.serbiosoc.org.rs/arch/index.php/abs/article/view/2841
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3226
AB  - In recent years, computed tomography (CT) has become very common in veterinary medicine. It is well known that testicles are organs with high radiosensitivity and their function can be impaired even after exposure to low radiation doses. In this work, we calculated the absorbed radiation doses after CT was performed with different voltage/current levels and correlated it with the activity of antioxidant enzymes in rabbit testicles. Two hours after CT, the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were increased in the testicles of animals that received an absorbed dose of 29.2 mGy. The same changes, along with elevated glutathione reductase (GR) activity, were observed after 7 days in animals that received the highest absorbed dose (46.3 mGy). It would appear that absorbed doses above 27.8 mGy provoked the antioxidant reaction but the time scale of the reaction was dose-dependent. Examination of the obtained results revealed that the main denominator of CT influence was a higher current. Our results suggest that CT influences the antioxidant status in rabbit testicles. The changes in antioxidant enzyme activities were dose- and time-dependent and influenced by the applied current.
T2  - Archives of Biological Sciences
T1  - Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles
IS  - 4
VL  - 70
DO  - 10.2298/ABS180413029M
SP  - 675
EP  - 680
ER  - 

@article{
author = "Mitrović, Marko and Tatalović, Nikola and Nikolić-Kokić, Aleksandra and Ciraj-Bjelac, Olivera and Krstić, Nikola and Oreščanin Dušić, Zorana and Krstić, Dragana and Jovanović, Zoran and Blagojević, Duško and Lazarević-Macanović, Mirjana",
year = "2018",
abstract = "In recent years, computed tomography (CT) has become very common in veterinary medicine. It is well known that testicles are organs with high radiosensitivity and their function can be impaired even after exposure to low radiation doses. In this work, we calculated the absorbed radiation doses after CT was performed with different voltage/current levels and correlated it with the activity of antioxidant enzymes in rabbit testicles. Two hours after CT, the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were increased in the testicles of animals that received an absorbed dose of 29.2 mGy. The same changes, along with elevated glutathione reductase (GR) activity, were observed after 7 days in animals that received the highest absorbed dose (46.3 mGy). It would appear that absorbed doses above 27.8 mGy provoked the antioxidant reaction but the time scale of the reaction was dose-dependent. Examination of the obtained results revealed that the main denominator of CT influence was a higher current. Our results suggest that CT influences the antioxidant status in rabbit testicles. The changes in antioxidant enzyme activities were dose- and time-dependent and influenced by the applied current.",
journal = "Archives of Biological Sciences",
title = "Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles",
number = "4",
volume = "70",
doi = "10.2298/ABS180413029M",
pages = "675-680"
}

Mitrović, M., Tatalović, N., Nikolić-Kokić, A., Ciraj-Bjelac, O., Krstić, N., Oreščanin Dušić, Z., Krstić, D., Jovanović, Z., Blagojević, D.,& Lazarević-Macanović, M.. (2018). Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles. in Archives of Biological Sciences, 70(4), 675-680.
https://doi.org/10.2298/ABS180413029M

Mitrović M, Tatalović N, Nikolić-Kokić A, Ciraj-Bjelac O, Krstić N, Oreščanin Dušić Z, Krstić D, Jovanović Z, Blagojević D, Lazarević-Macanović M. Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles. in Archives of Biological Sciences. 2018;70(4):675-680.
doi:10.2298/ABS180413029M .

Mitrović, Marko, Tatalović, Nikola, Nikolić-Kokić, Aleksandra, Ciraj-Bjelac, Olivera, Krstić, Nikola, Oreščanin Dušić, Zorana, Krstić, Dragana, Jovanović, Zoran, Blagojević, Duško, Lazarević-Macanović, Mirjana, "Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles" in Archives of Biological Sciences, 70, no. 4 (2018):675-680,
https://doi.org/10.2298/ABS180413029M . .