TY  - JOUR
AU  - Bertéli, Míria Benetati Delgado
AU  - Barros, Lillian
AU  - Reis, Filipa S.
AU  - Ferreira, Isabel C. F. R.
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
AU  - Valle, Juliana Silveira
AU  - Linde, Giani Andrea
AU  - Ruiz, Suelen Pereira
AU  - Colauto, Nelson Barros
PY  - 2021
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4301
AB  - Lentinus crinitus (L.) Fr. (Basidiomycota: Polyporales) is a wild mushroom with several biotechnological
applications; however, there are few studies on its chemical composition and antimicrobial activity.
Therefore, this study aims to evaluate the chemical composition, cytotoxicity, and antimicrobial activity of
L. crinitus basidiocarp. For that, its nutritional value (AOAC procedures) and its composition in some
hydrophilic and lipophilic compounds (chromatographic techniques) were assessed. Moreover, the
potential hepatotoxic effects were evaluated using a primary cell culture obtained from porcine liver, and
its growth inhibitory capacity was also evaluated against four human tumour cell lines (spectrophotometric
assays). The antimicrobial activity was evaluated by microdilution against eight bacteria and fungi.
The basidiocarp has a high content of carbohydrates and, therefore, a relatively high energetic value. It is
also rich in soluble sugars, β-tocopherol, phenolic acids, mainly p-hydroxybenzoic acid, and organic
acids, mainly malic acid. L. crinitus did not show cytotoxicity in non-tumour cells, but it did not inhibit the
growth of human tumour cell lines either. The basidiocarp has a wide antimicrobial activity, inhibiting the
growth of different species of bacteria and fungi. It showed minimum bactericidal and fungicidal concentration values similar to or lower than those verified by commercial antibiotics or food additives used as preservatives. The antimicrobial activity was more evident against Listeria monocytogenes, Salmonella enterica, and Penicillium ochrochloron, followed by Aspergillus ochraceus and Trichoderma viride, when compared to the controls. The results obtained in this study showed that L. crinitus basidiocarp has great potential to be used by the industry without toxicity risks.
PB  - The Royal Society of Chemistry
T2  - Food & Function
T1  - Antimicrobial activity, chemical composition and cytotoxicity of Lentinus crinitus basidiocarp
DO  - 10.1039/d1fo00656h
ER  - 

@article{
author = "Bertéli, Míria Benetati Delgado and Barros, Lillian and Reis, Filipa S. and Ferreira, Isabel C. F. R. and Glamočlija, Jasmina and Soković, Marina and Valle, Juliana Silveira and Linde, Giani Andrea and Ruiz, Suelen Pereira and Colauto, Nelson Barros",
year = "2021",
abstract = "Lentinus crinitus (L.) Fr. (Basidiomycota: Polyporales) is a wild mushroom with several biotechnological
applications; however, there are few studies on its chemical composition and antimicrobial activity.
Therefore, this study aims to evaluate the chemical composition, cytotoxicity, and antimicrobial activity of
L. crinitus basidiocarp. For that, its nutritional value (AOAC procedures) and its composition in some
hydrophilic and lipophilic compounds (chromatographic techniques) were assessed. Moreover, the
potential hepatotoxic effects were evaluated using a primary cell culture obtained from porcine liver, and
its growth inhibitory capacity was also evaluated against four human tumour cell lines (spectrophotometric
assays). The antimicrobial activity was evaluated by microdilution against eight bacteria and fungi.
The basidiocarp has a high content of carbohydrates and, therefore, a relatively high energetic value. It is
also rich in soluble sugars, β-tocopherol, phenolic acids, mainly p-hydroxybenzoic acid, and organic
acids, mainly malic acid. L. crinitus did not show cytotoxicity in non-tumour cells, but it did not inhibit the
growth of human tumour cell lines either. The basidiocarp has a wide antimicrobial activity, inhibiting the
growth of different species of bacteria and fungi. It showed minimum bactericidal and fungicidal concentration values similar to or lower than those verified by commercial antibiotics or food additives used as preservatives. The antimicrobial activity was more evident against Listeria monocytogenes, Salmonella enterica, and Penicillium ochrochloron, followed by Aspergillus ochraceus and Trichoderma viride, when compared to the controls. The results obtained in this study showed that L. crinitus basidiocarp has great potential to be used by the industry without toxicity risks.",
publisher = "The Royal Society of Chemistry",
journal = "Food & Function",
title = "Antimicrobial activity, chemical composition and cytotoxicity of Lentinus crinitus basidiocarp",
doi = "10.1039/d1fo00656h"
}

Bertéli, M. B. D., Barros, L., Reis, F. S., Ferreira, I. C. F. R., Glamočlija, J., Soković, M., Valle, J. S., Linde, G. A., Ruiz, S. P.,& Colauto, N. B.. (2021). Antimicrobial activity, chemical composition and cytotoxicity of Lentinus crinitus basidiocarp. in Food & Function
The Royal Society of Chemistry..
https://doi.org/10.1039/d1fo00656h

Bertéli MBD, Barros L, Reis FS, Ferreira ICFR, Glamočlija J, Soković M, Valle JS, Linde GA, Ruiz SP, Colauto NB. Antimicrobial activity, chemical composition and cytotoxicity of Lentinus crinitus basidiocarp. in Food & Function. 2021;.
doi:10.1039/d1fo00656h .

Bertéli, Míria Benetati Delgado, Barros, Lillian, Reis, Filipa S., Ferreira, Isabel C. F. R., Glamočlija, Jasmina, Soković, Marina, Valle, Juliana Silveira, Linde, Giani Andrea, Ruiz, Suelen Pereira, Colauto, Nelson Barros, "Antimicrobial activity, chemical composition and cytotoxicity of Lentinus crinitus basidiocarp" in Food & Function (2021),
https://doi.org/10.1039/d1fo00656h . .