TY  - JOUR
AU  - Brčić Karačonji, Irena
AU  - Jurica, Karlo
AU  - Gašić, Uroš
AU  - Dramićanin, Aleksandra
AU  - Tešić, Živoslav
AU  - Milojković Opsenica, Dušanka
PY  - 2022
UR  - https://www.mdpi.com/2223-7747/11/1/25
UR  - http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC8747429
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4758
AB  - The strawberry tree (Arbutus unedo L., Ericaceae family) is an evergreen Mediterranean shrub whose leaves and fruits are used in traditional medicine due to their antioxidant, antimicrobial, antidiabetic, diuretic, and antiproliferative properties. The health benefits are mainly attributed to the presence of phenolic compounds. The aim of this study was to compare the phenolic profiles, total phenolic content (TPC), and radical scavenging activity (RSA) of A. unedo leaves and fruits collected at two locations in Croatia. Phenolic profiles were identified using an ultra-high-performance liquid chromatograph (UHPLC) coupled with a hybrid mass spectrometer (LTQ Orbitrap MS). TPC was determined by Folin-Ciocalteu's assay, while RSA was investigated using DPPH reagent. A total of 64 phenolics (60 and 42 compounds in leaves and fruits, respectively) were identified. Hyperoside and flavan-3-ols were predominant compounds in leaves, while gallocatechin and catechin were the major compounds found in fruits. To the authors' knowledge, 16 and 5 phenolics in leaves and fruits, respectively, were reported for the first time. Principal component analysis (PCA) showed that UHPLC-LTQ Orbitrap MS could be used to identify which phenolics were able to discriminate samples regarding plant tissue and geographical origin. TPC in leaves and fruits were in the ranges of 67.07-104.74 and 16.78-25.86 mg gallic acid equivalents (GAE)/g dried weight (dw), respectively. RSA for leaves and fruits were in the ranges of 408.92-430.98 and 74.30-104.04 μmol Trolox equivalents (TE)/g dw, respectively. The number of identified phenolics was lower in fruits compared to leaves. Such a large number of bioactive phenolics identified and the strong antioxidant activity pointed to A. unedo as a promising health-promoting plant and natural food preservative.
PB  - Basel: MDPI
T2  - Plants (Basel, Switzerland)
T1  - Comparative Study on the Phenolic Fingerprint and Antioxidant Activity of Strawberry Tree (Arbutus unedo L.) Leaves and Fruits.
IS  - 1
VL  - 11
DO  - 10.3390/plants11010025
SP  - 25
ER  - 

@article{
author = "Brčić Karačonji, Irena and Jurica, Karlo and Gašić, Uroš and Dramićanin, Aleksandra and Tešić, Živoslav and Milojković Opsenica, Dušanka",
year = "2022",
abstract = "The strawberry tree (Arbutus unedo L., Ericaceae family) is an evergreen Mediterranean shrub whose leaves and fruits are used in traditional medicine due to their antioxidant, antimicrobial, antidiabetic, diuretic, and antiproliferative properties. The health benefits are mainly attributed to the presence of phenolic compounds. The aim of this study was to compare the phenolic profiles, total phenolic content (TPC), and radical scavenging activity (RSA) of A. unedo leaves and fruits collected at two locations in Croatia. Phenolic profiles were identified using an ultra-high-performance liquid chromatograph (UHPLC) coupled with a hybrid mass spectrometer (LTQ Orbitrap MS). TPC was determined by Folin-Ciocalteu's assay, while RSA was investigated using DPPH reagent. A total of 64 phenolics (60 and 42 compounds in leaves and fruits, respectively) were identified. Hyperoside and flavan-3-ols were predominant compounds in leaves, while gallocatechin and catechin were the major compounds found in fruits. To the authors' knowledge, 16 and 5 phenolics in leaves and fruits, respectively, were reported for the first time. Principal component analysis (PCA) showed that UHPLC-LTQ Orbitrap MS could be used to identify which phenolics were able to discriminate samples regarding plant tissue and geographical origin. TPC in leaves and fruits were in the ranges of 67.07-104.74 and 16.78-25.86 mg gallic acid equivalents (GAE)/g dried weight (dw), respectively. RSA for leaves and fruits were in the ranges of 408.92-430.98 and 74.30-104.04 μmol Trolox equivalents (TE)/g dw, respectively. The number of identified phenolics was lower in fruits compared to leaves. Such a large number of bioactive phenolics identified and the strong antioxidant activity pointed to A. unedo as a promising health-promoting plant and natural food preservative.",
publisher = "Basel: MDPI",
journal = "Plants (Basel, Switzerland)",
title = "Comparative Study on the Phenolic Fingerprint and Antioxidant Activity of Strawberry Tree (Arbutus unedo L.) Leaves and Fruits.",
number = "1",
volume = "11",
doi = "10.3390/plants11010025",
pages = "25"
}

Brčić Karačonji, I., Jurica, K., Gašić, U., Dramićanin, A., Tešić, Ž.,& Milojković Opsenica, D.. (2022). Comparative Study on the Phenolic Fingerprint and Antioxidant Activity of Strawberry Tree (Arbutus unedo L.) Leaves and Fruits.. in Plants (Basel, Switzerland)
Basel: MDPI., 11(1), 25.
https://doi.org/10.3390/plants11010025

Brčić Karačonji I, Jurica K, Gašić U, Dramićanin A, Tešić Ž, Milojković Opsenica D. Comparative Study on the Phenolic Fingerprint and Antioxidant Activity of Strawberry Tree (Arbutus unedo L.) Leaves and Fruits.. in Plants (Basel, Switzerland). 2022;11(1):25.
doi:10.3390/plants11010025 .

Brčić Karačonji, Irena, Jurica, Karlo, Gašić, Uroš, Dramićanin, Aleksandra, Tešić, Živoslav, Milojković Opsenica, Dušanka, "Comparative Study on the Phenolic Fingerprint and Antioxidant Activity of Strawberry Tree (Arbutus unedo L.) Leaves and Fruits." in Plants (Basel, Switzerland), 11, no. 1 (2022):25,
https://doi.org/10.3390/plants11010025 . .

TY  - JOUR
AU  - Jurič, Andreja
AU  - Gašić, Uroš
AU  - Brčić Karačonji, Irena
AU  - Jurica, Karlo
AU  - Milojković-Opsenica, Dušanka
PY  - 2020
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3688
AB  - Despite of the many beneficial health effects of strawberry tree (Arbutus unedo L.) honey due to its strong antioxidant activity derived mostly from polyphenols, a detailed phenolic profile has not been previously studied. The aims of this study were to identify the phenolic compounds, determine the total phenolic content (TPC) and evaluate the radical scavenging activity (RSA) of strawberry tree honey from south Croatia. Fifty-two polyphenolics (twenty-seven phenolic acids and twenty-five flavonoids) were identified using ultra-high-performance liquid chromatograph (UHPLC) coupled to a hybrid mass spectrometer (LTQ Orbitrap MS). Our overall results point to higher TPC (1038 mg gallic acid equivalents per kg of honey) and stronger RSA (3.32 mmol Trolox equivalents per kg of honey) compared to other monofloral honeys. Due to the presence of large quantities of polyphenolic compounds, strawberry tree honey may have great potential as a health promoting food. Line
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - The phenolic profile of strawberry tree (Arbutus unedo L.) honey
IS  - 8
VL  - 85
DO  - 10.2298/JSC191217018J
SP  - 1011
EP  - 1019
ER  - 

@article{
author = "Jurič, Andreja and Gašić, Uroš and Brčić Karačonji, Irena and Jurica, Karlo and Milojković-Opsenica, Dušanka",
year = "2020",
abstract = "Despite of the many beneficial health effects of strawberry tree (Arbutus unedo L.) honey due to its strong antioxidant activity derived mostly from polyphenols, a detailed phenolic profile has not been previously studied. The aims of this study were to identify the phenolic compounds, determine the total phenolic content (TPC) and evaluate the radical scavenging activity (RSA) of strawberry tree honey from south Croatia. Fifty-two polyphenolics (twenty-seven phenolic acids and twenty-five flavonoids) were identified using ultra-high-performance liquid chromatograph (UHPLC) coupled to a hybrid mass spectrometer (LTQ Orbitrap MS). Our overall results point to higher TPC (1038 mg gallic acid equivalents per kg of honey) and stronger RSA (3.32 mmol Trolox equivalents per kg of honey) compared to other monofloral honeys. Due to the presence of large quantities of polyphenolic compounds, strawberry tree honey may have great potential as a health promoting food. Line",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "The phenolic profile of strawberry tree (Arbutus unedo L.) honey",
number = "8",
volume = "85",
doi = "10.2298/JSC191217018J",
pages = "1011-1019"
}

Jurič, A., Gašić, U., Brčić Karačonji, I., Jurica, K.,& Milojković-Opsenica, D.. (2020). The phenolic profile of strawberry tree (Arbutus unedo L.) honey. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 85(8), 1011-1019.
https://doi.org/10.2298/JSC191217018J

Jurič A, Gašić U, Brčić Karačonji I, Jurica K, Milojković-Opsenica D. The phenolic profile of strawberry tree (Arbutus unedo L.) honey. in Journal of the Serbian Chemical Society. 2020;85(8):1011-1019.
doi:10.2298/JSC191217018J .

Jurič, Andreja, Gašić, Uroš, Brčić Karačonji, Irena, Jurica, Karlo, Milojković-Opsenica, Dušanka, "The phenolic profile of strawberry tree (Arbutus unedo L.) honey" in Journal of the Serbian Chemical Society, 85, no. 8 (2020):1011-1019,
https://doi.org/10.2298/JSC191217018J . .