TY  - JOUR
AU  - Monje, Alberto
AU  - Insua, Angel
AU  - Rakić, Mia
AU  - Nart, Jose
AU  - Moyano-Cuevas, Jose Luis
AU  - Wang, Hom-Lay
PY  - 2018
UR  - http://doi.wiley.com/10.1002/JPER.18-0081
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3210
AB  - BACKGROUND Lack of consensus on the clinical parameters of peri-implantitis may complicate accurate diagnosis of the disorder. Furthermore, the lack of reliable estimates of the diagnostic capacity of the clinical endpoints precludes the definition of an effective treatment protocol for peri-implantitis. The present canine study assesses the diagnostic accuracy of the clinical parameters for monitoring the peri-implant tissues in a controlled ligature-induced peri-implantitis model followed by a spontaneous progression phase. METHODS Six beagle dogs were followed-up on during three episodes of ligature-induced peri-implantitis and a further episode of spontaneous progression. Probing depth (PD), bleeding on probing (BOP), mucosal recession (MR), and suppuration (SUP) were recorded at four sites per implant and at four study timepoints. Moreover, the implant mucosal index (IMI) was calculated at implant level. Marginal bone loss (MBL) was determined using computed tomography at four sites per implant. A linear regression model was used to estimate clinical and radiological parameters during peri-implantitis progression. RESULTS Progressive peri-implant bone loss is characterized by an increase in PD, more profuse BOP, MR, and SUP in advanced cases (p < 0.001). However, even in the presence of severe bone loss, SUP was not a common finding, with an incidence of approximately 10% at the last timepoint. These clinical parameters were significantly correlated to MBL at most of the timepoints. The IMI, in turn, showed a positive correlation to MBL and the peri-implant inflammatory signs (r = 0.39; p < 0.001), with a tendency to exhibit higher scores during ligature-induced peri-implantitis, followed by a slight decrease during the spontaneous progression period. CONCLUSION The clinical features of peri-implantitis and spontaneous progression of the disorder may facilitate an accurate monitoring of peri-implant pathologic bone loss.
T2  - Journal of Periodontology
T1  - Estimation of the diagnostic accuracy of clinical parameters for monitoring peri-implantitis progression: An experimental canine study.
IS  - 12
VL  - 89
DO  - 10.1002/JPER.18-0081
SP  - 1442
EP  - 1451
ER  - 

@article{
author = "Monje, Alberto and Insua, Angel and Rakić, Mia and Nart, Jose and Moyano-Cuevas, Jose Luis and Wang, Hom-Lay",
year = "2018",
abstract = "BACKGROUND Lack of consensus on the clinical parameters of peri-implantitis may complicate accurate diagnosis of the disorder. Furthermore, the lack of reliable estimates of the diagnostic capacity of the clinical endpoints precludes the definition of an effective treatment protocol for peri-implantitis. The present canine study assesses the diagnostic accuracy of the clinical parameters for monitoring the peri-implant tissues in a controlled ligature-induced peri-implantitis model followed by a spontaneous progression phase. METHODS Six beagle dogs were followed-up on during three episodes of ligature-induced peri-implantitis and a further episode of spontaneous progression. Probing depth (PD), bleeding on probing (BOP), mucosal recession (MR), and suppuration (SUP) were recorded at four sites per implant and at four study timepoints. Moreover, the implant mucosal index (IMI) was calculated at implant level. Marginal bone loss (MBL) was determined using computed tomography at four sites per implant. A linear regression model was used to estimate clinical and radiological parameters during peri-implantitis progression. RESULTS Progressive peri-implant bone loss is characterized by an increase in PD, more profuse BOP, MR, and SUP in advanced cases (p < 0.001). However, even in the presence of severe bone loss, SUP was not a common finding, with an incidence of approximately 10% at the last timepoint. These clinical parameters were significantly correlated to MBL at most of the timepoints. The IMI, in turn, showed a positive correlation to MBL and the peri-implant inflammatory signs (r = 0.39; p < 0.001), with a tendency to exhibit higher scores during ligature-induced peri-implantitis, followed by a slight decrease during the spontaneous progression period. CONCLUSION The clinical features of peri-implantitis and spontaneous progression of the disorder may facilitate an accurate monitoring of peri-implant pathologic bone loss.",
journal = "Journal of Periodontology",
title = "Estimation of the diagnostic accuracy of clinical parameters for monitoring peri-implantitis progression: An experimental canine study.",
number = "12",
volume = "89",
doi = "10.1002/JPER.18-0081",
pages = "1442-1451"
}

Monje, A., Insua, A., Rakić, M., Nart, J., Moyano-Cuevas, J. L.,& Wang, H.. (2018). Estimation of the diagnostic accuracy of clinical parameters for monitoring peri-implantitis progression: An experimental canine study.. in Journal of Periodontology, 89(12), 1442-1451.
https://doi.org/10.1002/JPER.18-0081

Monje A, Insua A, Rakić M, Nart J, Moyano-Cuevas JL, Wang H. Estimation of the diagnostic accuracy of clinical parameters for monitoring peri-implantitis progression: An experimental canine study.. in Journal of Periodontology. 2018;89(12):1442-1451.
doi:10.1002/JPER.18-0081 .

Monje, Alberto, Insua, Angel, Rakić, Mia, Nart, Jose, Moyano-Cuevas, Jose Luis, Wang, Hom-Lay, "Estimation of the diagnostic accuracy of clinical parameters for monitoring peri-implantitis progression: An experimental canine study." in Journal of Periodontology, 89, no. 12 (2018):1442-1451,
https://doi.org/10.1002/JPER.18-0081 . .