TY  - JOUR
AU  - Pitta, Eleni
AU  - Tsolaki, Evangelia
AU  - Geronikaki, Athina
AU  - Petrović, Jovana
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
AU  - Crespan, Emmanuele
AU  - Maga, Giovanni
AU  - Bhunia, Shome S.
AU  - Saxena, Anil K.
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2088
AB  - As a part of our ongoing research in the development of new
   antimicrobials, herein, we report the synthesis of ten compounds which
   combine three bioactive moieties: thiazole, adamantane and
   4-thiazolidinone. Evaluation of their antibacterial activity revealed
   that the newly synthesized compounds exhibited remarkable growth
   inhibition of a wide spectrum of Gram-positive bacteria, Gram-negative
   bacteria and fungi. The majority of the compounds displayed greater
   antibacterial activity than the reference drugs (ampicillin and
   streptomycin), while the antifungal activity was significantly higher
   than that of the reference drugs bifonazole and ketoconazole.
   Additionally, the title compounds were screened for HIV-1 reverse
   transcriptase inhibitory activity, showing no significant activity.
   Moreover, docking studies were performed in order to explore possible
   binding modes at the MurB protein of S. aureus.
T2  - Medchemcomm
T1  - 4-Thiazolidinone derivatives as potent antimicrobial agents:
 microwave-assisted synthesis, biological evaluation and docking studies
IS  - 2
VL  - 6
DO  - 10.1039/c4md00399c
SP  - 319
EP  - 326
ER  - 

@article{
author = "Pitta, Eleni and Tsolaki, Evangelia and Geronikaki, Athina and Petrović, Jovana and Glamočlija, Jasmina and Soković, Marina and Crespan, Emmanuele and Maga, Giovanni and Bhunia, Shome S. and Saxena, Anil K.",
year = "2015",
abstract = "As a part of our ongoing research in the development of new
   antimicrobials, herein, we report the synthesis of ten compounds which
   combine three bioactive moieties: thiazole, adamantane and
   4-thiazolidinone. Evaluation of their antibacterial activity revealed
   that the newly synthesized compounds exhibited remarkable growth
   inhibition of a wide spectrum of Gram-positive bacteria, Gram-negative
   bacteria and fungi. The majority of the compounds displayed greater
   antibacterial activity than the reference drugs (ampicillin and
   streptomycin), while the antifungal activity was significantly higher
   than that of the reference drugs bifonazole and ketoconazole.
   Additionally, the title compounds were screened for HIV-1 reverse
   transcriptase inhibitory activity, showing no significant activity.
   Moreover, docking studies were performed in order to explore possible
   binding modes at the MurB protein of S. aureus.",
journal = "Medchemcomm",
title = "4-Thiazolidinone derivatives as potent antimicrobial agents:
 microwave-assisted synthesis, biological evaluation and docking studies",
number = "2",
volume = "6",
doi = "10.1039/c4md00399c",
pages = "319-326"
}

Pitta, E., Tsolaki, E., Geronikaki, A., Petrović, J., Glamočlija, J., Soković, M., Crespan, E., Maga, G., Bhunia, S. S.,& Saxena, A. K.. (2015). 4-Thiazolidinone derivatives as potent antimicrobial agents:
 microwave-assisted synthesis, biological evaluation and docking studies. in Medchemcomm, 6(2), 319-326.
https://doi.org/10.1039/c4md00399c

Pitta E, Tsolaki E, Geronikaki A, Petrović J, Glamočlija J, Soković M, Crespan E, Maga G, Bhunia SS, Saxena AK. 4-Thiazolidinone derivatives as potent antimicrobial agents:
 microwave-assisted synthesis, biological evaluation and docking studies. in Medchemcomm. 2015;6(2):319-326.
doi:10.1039/c4md00399c .

Pitta, Eleni, Tsolaki, Evangelia, Geronikaki, Athina, Petrović, Jovana, Glamočlija, Jasmina, Soković, Marina, Crespan, Emmanuele, Maga, Giovanni, Bhunia, Shome S., Saxena, Anil K., "4-Thiazolidinone derivatives as potent antimicrobial agents:
 microwave-assisted synthesis, biological evaluation and docking studies" in Medchemcomm, 6, no. 2 (2015):319-326,
https://doi.org/10.1039/c4md00399c . .