TY  - JOUR
AU  - Saičić, Zorica
AU  - Radojičić, Ratko M.
AU  - Spasić, Snežana D.
AU  - Jovanović, Tamara B.
AU  - Simić-Krstić, Jovana B.
PY  - 2004
PY  - 2004
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/549
AB  - The C3 clone of B-16 mouse melanoma was cultured for 1, 6 and 9 days and analyzed. The changes which are not directly linked to melanogenesis in the B-16 / C3 cultures during their maturation were characterized. Early (1 day) confluent (6 days) and old (9 days) cell cultures are distinguished by their leucine aminopeptidase (LAP) and α-naphthyl acetate esterase (ANAE) isoenzyme patterns. Both quantitative and qualitative changes in LAP and ANAE isoenzyme can be observed during culture maturation. There is an increase in the activity of the enzyme copper, zinc-containing superoxide-dismutase (CuZn SOD). The increaase in the CuZn SOD enzyme activity might be related to B-16/C3 cell melanogenesis and / or to differentiation.
AB  - C3 klonovi B-16 melanoma miša su gajeni u kulturi 1, 6 i 9 dana i potom analizirani. Izvršena je karakterizacija promena B-16/C3 ćelijskih kultura tokom njihove maturacije koje nisu direktno povezane sa melanogenezom. Pokazano je da se kulture u početnoj fazi (1 dan), konfluentnoj fazi (6 dana) i kasnoj fazi (9 dana) ćelijskog rasta razlikuju na osnovu izoenzimskih spektara leucin-aminopeptidaze i alfa-naftil-acetat-esteraze. Tokom razvitka ćelijskih kultura B-16/C3 zapažene su kvantitativne i kvalitativne promene leucin-aminopeptidaze i alfa-naftil-acetat-esteraze u njihovim izoenzimskim spektrima. Utvrđeno je da postoji porast aktivnosti bakar-cink superoksid-dismutaze tokom starenja kulture. Porast aktivnosti bakar-cink superoksid-dismutaze može biti povezan sa melanogenezom i/ili diferencijacijom B-16/C3 ćelija.
T2  - Journal of the Serbian Chemical Society
T1  - Aktivnost superoksid-dismutaze tokom maturacije kulture ćelija b-16 melanoma miša
T1  - Superoxide dismutase activity as a function of culture aging of B-16 mouse melanoma cells
IS  - 12
VL  - 69
SP  - 1005
EP  - 1011
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_549
ER  - 

@article{
author = "Saičić, Zorica and Radojičić, Ratko M. and Spasić, Snežana D. and Jovanović, Tamara B. and Simić-Krstić, Jovana B.",
year = "2004, 2004",
abstract = "The C3 clone of B-16 mouse melanoma was cultured for 1, 6 and 9 days and analyzed. The changes which are not directly linked to melanogenesis in the B-16 / C3 cultures during their maturation were characterized. Early (1 day) confluent (6 days) and old (9 days) cell cultures are distinguished by their leucine aminopeptidase (LAP) and α-naphthyl acetate esterase (ANAE) isoenzyme patterns. Both quantitative and qualitative changes in LAP and ANAE isoenzyme can be observed during culture maturation. There is an increase in the activity of the enzyme copper, zinc-containing superoxide-dismutase (CuZn SOD). The increaase in the CuZn SOD enzyme activity might be related to B-16/C3 cell melanogenesis and / or to differentiation., C3 klonovi B-16 melanoma miša su gajeni u kulturi 1, 6 i 9 dana i potom analizirani. Izvršena je karakterizacija promena B-16/C3 ćelijskih kultura tokom njihove maturacije koje nisu direktno povezane sa melanogenezom. Pokazano je da se kulture u početnoj fazi (1 dan), konfluentnoj fazi (6 dana) i kasnoj fazi (9 dana) ćelijskog rasta razlikuju na osnovu izoenzimskih spektara leucin-aminopeptidaze i alfa-naftil-acetat-esteraze. Tokom razvitka ćelijskih kultura B-16/C3 zapažene su kvantitativne i kvalitativne promene leucin-aminopeptidaze i alfa-naftil-acetat-esteraze u njihovim izoenzimskim spektrima. Utvrđeno je da postoji porast aktivnosti bakar-cink superoksid-dismutaze tokom starenja kulture. Porast aktivnosti bakar-cink superoksid-dismutaze može biti povezan sa melanogenezom i/ili diferencijacijom B-16/C3 ćelija.",
journal = "Journal of the Serbian Chemical Society",
title = "Aktivnost superoksid-dismutaze tokom maturacije kulture ćelija b-16 melanoma miša, Superoxide dismutase activity as a function of culture aging of B-16 mouse melanoma cells",
number = "12",
volume = "69",
pages = "1005-1011",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_549"
}

Saičić, Z., Radojičić, R. M., Spasić, S. D., Jovanović, T. B.,& Simić-Krstić, J. B.. (2004). Aktivnost superoksid-dismutaze tokom maturacije kulture ćelija b-16 melanoma miša. in Journal of the Serbian Chemical Society, 69(12), 1005-1011.
https://hdl.handle.net/21.15107/rcub_ibiss_549

Saičić Z, Radojičić RM, Spasić SD, Jovanović TB, Simić-Krstić JB. Aktivnost superoksid-dismutaze tokom maturacije kulture ćelija b-16 melanoma miša. in Journal of the Serbian Chemical Society. 2004;69(12):1005-1011.
https://hdl.handle.net/21.15107/rcub_ibiss_549 .

Saičić, Zorica, Radojičić, Ratko M., Spasić, Snežana D., Jovanović, Tamara B., Simić-Krstić, Jovana B., "Aktivnost superoksid-dismutaze tokom maturacije kulture ćelija b-16 melanoma miša" in Journal of the Serbian Chemical Society, 69, no. 12 (2004):1005-1011,
https://hdl.handle.net/21.15107/rcub_ibiss_549 .