TY  - JOUR
AU  - Đurašević, Siniša
AU  - Pejić, Snežana
AU  - Grigorov, Ilijana
AU  - Nikolić, Gorana
AU  - Mitić-Ćulafić, Dragana
AU  - Dragićević, Milan
AU  - Đorđević, Jelena
AU  - Todorović Vukotić, Nevena
AU  - Đorđević, Neda
AU  - Todorović, Ana
AU  - Drakulić, Dunja
AU  - Veljković, Filip
AU  - Pajović, Snežana B.
AU  - Todorović, Zoran
PY  - 2021
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4289
AB  - Thioacetamide (TAA) is widely used to study liver toxicity accompanied by oxidative stress, inflammation, cell necrosis, fibrosis, cholestasis, and hepatocellular carcinoma. As an efficient free radical’s scavenger, C60 fullerene is considered a potential liver-protective agent in chemically-induced liver injury. In the present work, we examined the hepatoprotective effects of two C60 doses dissolved in virgin olive oil against TAA-induced hepatotoxicity in rats. We showed that TAA-induced increase in liver oxidative stress, judged by the changes in the activities of SOD, CAT, GPx, GR, GST, the content of GSH and 4-HNE, and expression of HO-1, MnSOD, and CuZnSOD, was more effectively ameliorated with a lower C60 dose. Improvement in liver antioxidative status caused by C60 was accompanied by a decrease in liver HMGB1 expression and an increase in nuclear Nrf2/NF-κB p65 ratio, suggesting a reduction in inflammation, necrosis and fibrosis. These results were in accordance with liver histology analysis, liver comet assay, and changes in serum levels of ALT, AST, and AP. The changes observed in gut microbiome support detrimental effects of TAA and hepatoprotective effects of low C60 dose. Less protective effects of a higher C60 dose could be a consequence of its enhanced aggregation and related pro-oxidant role.
PB  - MDPI
T2  - Antioxidants
T1  - Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes
IS  - 6
VL  - 10
DO  - 10.3390/antiox10060911
SP  - 911
ER  - 

@article{
author = "Đurašević, Siniša and Pejić, Snežana and Grigorov, Ilijana and Nikolić, Gorana and Mitić-Ćulafić, Dragana and Dragićević, Milan and Đorđević, Jelena and Todorović Vukotić, Nevena and Đorđević, Neda and Todorović, Ana and Drakulić, Dunja and Veljković, Filip and Pajović, Snežana B. and Todorović, Zoran",
year = "2021",
abstract = "Thioacetamide (TAA) is widely used to study liver toxicity accompanied by oxidative stress, inflammation, cell necrosis, fibrosis, cholestasis, and hepatocellular carcinoma. As an efficient free radical’s scavenger, C60 fullerene is considered a potential liver-protective agent in chemically-induced liver injury. In the present work, we examined the hepatoprotective effects of two C60 doses dissolved in virgin olive oil against TAA-induced hepatotoxicity in rats. We showed that TAA-induced increase in liver oxidative stress, judged by the changes in the activities of SOD, CAT, GPx, GR, GST, the content of GSH and 4-HNE, and expression of HO-1, MnSOD, and CuZnSOD, was more effectively ameliorated with a lower C60 dose. Improvement in liver antioxidative status caused by C60 was accompanied by a decrease in liver HMGB1 expression and an increase in nuclear Nrf2/NF-κB p65 ratio, suggesting a reduction in inflammation, necrosis and fibrosis. These results were in accordance with liver histology analysis, liver comet assay, and changes in serum levels of ALT, AST, and AP. The changes observed in gut microbiome support detrimental effects of TAA and hepatoprotective effects of low C60 dose. Less protective effects of a higher C60 dose could be a consequence of its enhanced aggregation and related pro-oxidant role.",
publisher = "MDPI",
journal = "Antioxidants",
title = "Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes",
number = "6",
volume = "10",
doi = "10.3390/antiox10060911",
pages = "911"
}

Đurašević, S., Pejić, S., Grigorov, I., Nikolić, G., Mitić-Ćulafić, D., Dragićević, M., Đorđević, J., Todorović Vukotić, N., Đorđević, N., Todorović, A., Drakulić, D., Veljković, F., Pajović, S. B.,& Todorović, Z.. (2021). Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes. in Antioxidants
MDPI., 10(6), 911.
https://doi.org/10.3390/antiox10060911

Đurašević S, Pejić S, Grigorov I, Nikolić G, Mitić-Ćulafić D, Dragićević M, Đorđević J, Todorović Vukotić N, Đorđević N, Todorović A, Drakulić D, Veljković F, Pajović SB, Todorović Z. Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes. in Antioxidants. 2021;10(6):911.
doi:10.3390/antiox10060911 .

Đurašević, Siniša, Pejić, Snežana, Grigorov, Ilijana, Nikolić, Gorana, Mitić-Ćulafić, Dragana, Dragićević, Milan, Đorđević, Jelena, Todorović Vukotić, Nevena, Đorđević, Neda, Todorović, Ana, Drakulić, Dunja, Veljković, Filip, Pajović, Snežana B., Todorović, Zoran, "Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes" in Antioxidants, 10, no. 6 (2021):911,
https://doi.org/10.3390/antiox10060911 . .

TY  - JOUR
AU  - Gavrilović, Branka
AU  - Despotović, Svetlana
AU  - Radovanović, Tijana
AU  - Gavrić, Jelena
AU  - Borković Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Ognjanović, Branka I.
AU  - Simić, Snežana B.
AU  - Pajović, Snežana B.
AU  - Saičić, Zorica
PY  - 2011
PY  - 2011
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/292
AB  - We investigated the biochemical and ultrastructural changes in the liver of the freshwater fish, European perch (Perca fluviatilis), in response to Aphanizomenon flos-aquae bloom in the Gruža Reservoir, Serbia. The activities of total manganese- and copper zinc-containing superoxide dismutase (Tot SOD, Mn-SOD, Cu/Zn-SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and biotransformation phase II enzyme glutathione-S-transferase (GST), as well as concentrations of total glutathione (GSH) and sulfhydryl (-SH) groups were examined before and during the bloom period. Mn-SOD activity was significantly higher, while the activities of Cu/Zn-SOD, CAT and GSH-Px and the concentration of the -SH groups were significantly lower during the bloom. The ultrastructure of the liver revealed necrotic and apoptotic damage to the hepatocytes during the bloom period. Our work represents the first study to report the influences of an Aphanizomenon flos-aquae bloom in the Gruža Reservoir on antioxidant biomarkers and on histopathological alterations in the liver of the freshwater fish European perch (Perca fluviatilis).
T2  - Archives of Biological Sciences
T1  - Biochemical and ultrastructural changes in the liver of European perch (Perca fluviatilis L.) in response to cyanobacterial bloom in the Gruža reservoir
IS  - 4
VL  - 63
DO  - 10.2298/ABS1104979P
SP  - 979
EP  - 989
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_292
ER  - 

@article{
author = "Gavrilović, Branka and Despotović, Svetlana and Radovanović, Tijana and Gavrić, Jelena and Borković Mitić, Slavica and Pavlović, Slađan and Ognjanović, Branka I. and Simić, Snežana B. and Pajović, Snežana B. and Saičić, Zorica",
year = "2011, 2011",
abstract = "We investigated the biochemical and ultrastructural changes in the liver of the freshwater fish, European perch (Perca fluviatilis), in response to Aphanizomenon flos-aquae bloom in the Gruža Reservoir, Serbia. The activities of total manganese- and copper zinc-containing superoxide dismutase (Tot SOD, Mn-SOD, Cu/Zn-SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and biotransformation phase II enzyme glutathione-S-transferase (GST), as well as concentrations of total glutathione (GSH) and sulfhydryl (-SH) groups were examined before and during the bloom period. Mn-SOD activity was significantly higher, while the activities of Cu/Zn-SOD, CAT and GSH-Px and the concentration of the -SH groups were significantly lower during the bloom. The ultrastructure of the liver revealed necrotic and apoptotic damage to the hepatocytes during the bloom period. Our work represents the first study to report the influences of an Aphanizomenon flos-aquae bloom in the Gruža Reservoir on antioxidant biomarkers and on histopathological alterations in the liver of the freshwater fish European perch (Perca fluviatilis).",
journal = "Archives of Biological Sciences",
title = "Biochemical and ultrastructural changes in the liver of European perch (Perca fluviatilis L.) in response to cyanobacterial bloom in the Gruža reservoir",
number = "4",
volume = "63",
doi = "10.2298/ABS1104979P",
pages = "979-989",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_292"
}

Gavrilović, B., Despotović, S., Radovanović, T., Gavrić, J., Borković Mitić, S., Pavlović, S., Ognjanović, B. I., Simić, S. B., Pajović, S. B.,& Saičić, Z.. (2011). Biochemical and ultrastructural changes in the liver of European perch (Perca fluviatilis L.) in response to cyanobacterial bloom in the Gruža reservoir. in Archives of Biological Sciences, 63(4), 979-989.
https://doi.org/10.2298/ABS1104979P
https://hdl.handle.net/21.15107/rcub_ibiss_292

Gavrilović B, Despotović S, Radovanović T, Gavrić J, Borković Mitić S, Pavlović S, Ognjanović BI, Simić SB, Pajović SB, Saičić Z. Biochemical and ultrastructural changes in the liver of European perch (Perca fluviatilis L.) in response to cyanobacterial bloom in the Gruža reservoir. in Archives of Biological Sciences. 2011;63(4):979-989.
doi:10.2298/ABS1104979P
https://hdl.handle.net/21.15107/rcub_ibiss_292 .

Gavrilović, Branka, Despotović, Svetlana, Radovanović, Tijana, Gavrić, Jelena, Borković Mitić, Slavica, Pavlović, Slađan, Ognjanović, Branka I., Simić, Snežana B., Pajović, Snežana B., Saičić, Zorica, "Biochemical and ultrastructural changes in the liver of European perch (Perca fluviatilis L.) in response to cyanobacterial bloom in the Gruža reservoir" in Archives of Biological Sciences, 63, no. 4 (2011):979-989,
https://doi.org/10.2298/ABS1104979P .,
https://hdl.handle.net/21.15107/rcub_ibiss_292 .

TY  - CONF
AU  - Borković-Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Radovanović, Tijana
AU  - Gavrilović, Branka
AU  - Despotović, Svetlana
AU  - Gavrić, Jelena
AU  - Paunović, Momir
AU  - Pajović, Snežana
AU  - Saičić, Zorica
PY  - 2011
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5941
AB  - U nаšoj studiji ispitivali smo koncentraciju vitamina E i SH grupa u digestivnoj
žlezdi i škrgаmа slаtkovodne školjke Unio tumidus nа četiri lokаlitetа (Jаmenа, Sremskа
Mitrovicа, Šаbаc i Ostružnicа) nа reci Sаvi.
Kod slatkovodne školjke U. tumidus koncentracija vitamina E bila je statistički
značajno veća na lokalitetu Šabac i u digestivnoj žlezdi i škrgama u odnosu na druge
ispitivane lokalitete. Koncentracija SH grupa kod slаtkovodne školjke U. tumidus bila je
statistički značajno veća u digestivnoj žlezdi u poređenju sa škrgama na sva četiri
lokaliteta, a najveće vrednosti koncentracije SH grupa su zabeležene na lokalitetima
Šabac i Ostružnica. Dobijeni rezultаti u nаšoj studiji pokаzuju veliku specifičnost u
odnosu nа tkivo i lokаlitet, ukаzujući nа rаzličite metаboličke аktivnosti i rаznovrstаn
uticаj sredine. Naši podaci ukаzuju dа vаrijаcije u koncentraciji vitamina E i SH grupa
kod U. tumidus, takođe mogu biti korišćene zа molekularno fiziološki biomonitoring
životne sredine.
Nаša studija predstаvljа prvi obimаn izveštаj o koncentraciju vitamina E i SH
grupa kаo relevаntnih biohemijskih biomаrkera oksidаcionog stresа kod slаtkovodne
školjke U. tumidus nа rаzličitim ispitivanim lokаlitetimа nа reci Sаvi i obezbeđuje
osnovu zа budućа proučаvаnjа kojа će uzeti u obzir nаše pаrаmetre kаo potencijаlne
biohemijske biomаrkere zа molekularno fiziološki biomonitoring osnovnih sredinskih
uslovа i nekih аntropogenih uticаjа.
PB  - Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju
C3  - Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia
T1  - Koncentracija vitamina e i sh grupa kao biomarkera oksidacionog stresa u digestivnoj žlezdi i škrgama kod školjke Unio tumidus u reci Savi
SP  - 72
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5941
ER  - 

@conference{
author = "Borković-Mitić, Slavica and Pavlović, Slađan and Radovanović, Tijana and Gavrilović, Branka and Despotović, Svetlana and Gavrić, Jelena and Paunović, Momir and Pajović, Snežana and Saičić, Zorica",
year = "2011",
abstract = "U nаšoj studiji ispitivali smo koncentraciju vitamina E i SH grupa u digestivnoj
žlezdi i škrgаmа slаtkovodne školjke Unio tumidus nа četiri lokаlitetа (Jаmenа, Sremskа
Mitrovicа, Šаbаc i Ostružnicа) nа reci Sаvi.
Kod slatkovodne školjke U. tumidus koncentracija vitamina E bila je statistički
značajno veća na lokalitetu Šabac i u digestivnoj žlezdi i škrgama u odnosu na druge
ispitivane lokalitete. Koncentracija SH grupa kod slаtkovodne školjke U. tumidus bila je
statistički značajno veća u digestivnoj žlezdi u poređenju sa škrgama na sva četiri
lokaliteta, a najveće vrednosti koncentracije SH grupa su zabeležene na lokalitetima
Šabac i Ostružnica. Dobijeni rezultаti u nаšoj studiji pokаzuju veliku specifičnost u
odnosu nа tkivo i lokаlitet, ukаzujući nа rаzličite metаboličke аktivnosti i rаznovrstаn
uticаj sredine. Naši podaci ukаzuju dа vаrijаcije u koncentraciji vitamina E i SH grupa
kod U. tumidus, takođe mogu biti korišćene zа molekularno fiziološki biomonitoring
životne sredine.
Nаša studija predstаvljа prvi obimаn izveštаj o koncentraciju vitamina E i SH
grupa kаo relevаntnih biohemijskih biomаrkera oksidаcionog stresа kod slаtkovodne
školjke U. tumidus nа rаzličitim ispitivanim lokаlitetimа nа reci Sаvi i obezbeđuje
osnovu zа budućа proučаvаnjа kojа će uzeti u obzir nаše pаrаmetre kаo potencijаlne
biohemijske biomаrkere zа molekularno fiziološki biomonitoring osnovnih sredinskih
uslovа i nekih аntropogenih uticаjа.",
publisher = "Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju",
journal = "Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia",
title = "Koncentracija vitamina e i sh grupa kao biomarkera oksidacionog stresa u digestivnoj žlezdi i škrgama kod školjke Unio tumidus u reci Savi",
pages = "72",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5941"
}

Borković-Mitić, S., Pavlović, S., Radovanović, T., Gavrilović, B., Despotović, S., Gavrić, J., Paunović, M., Pajović, S.,& Saičić, Z.. (2011). Koncentracija vitamina e i sh grupa kao biomarkera oksidacionog stresa u digestivnoj žlezdi i škrgama kod školjke Unio tumidus u reci Savi. in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia
Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju., 72.
https://hdl.handle.net/21.15107/rcub_ibiss_5941

Borković-Mitić S, Pavlović S, Radovanović T, Gavrilović B, Despotović S, Gavrić J, Paunović M, Pajović S, Saičić Z. Koncentracija vitamina e i sh grupa kao biomarkera oksidacionog stresa u digestivnoj žlezdi i škrgama kod školjke Unio tumidus u reci Savi. in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia. 2011;:72.
https://hdl.handle.net/21.15107/rcub_ibiss_5941 .

Borković-Mitić, Slavica, Pavlović, Slađan, Radovanović, Tijana, Gavrilović, Branka, Despotović, Svetlana, Gavrić, Jelena, Paunović, Momir, Pajović, Snežana, Saičić, Zorica, "Koncentracija vitamina e i sh grupa kao biomarkera oksidacionog stresa u digestivnoj žlezdi i škrgama kod školjke Unio tumidus u reci Savi" in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia (2011):72,
https://hdl.handle.net/21.15107/rcub_ibiss_5941 .

TY  - CONF
AU  - Radovanović, Tijana
AU  - Gavrilović, Branka
AU  - Despotović, Svetlana
AU  - Gavrić, Jelena
AU  - Borković-Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Predrag, Cakić
AU  - Pajović, Snežana
AU  - Saičić, Zorica
PY  - 2011
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5943
AB  - U našoj studiji određivali smo sezonski zavisnu promenu u koncentraciji
vitamina E i SH grupa u škrgama, bubregu i crevu rečne mrene (Barbus barbus) iz
Dunava, koja predstavlja bentosnu ribu široke geografske distribucije. Istraživanja su
izvedena u prigradskom području Beograda, između Višnjice i Grocke, u prolećnoj i
letnjoj sezoni. Koncentracije ispitivanih parametara merene su standardnim
spektrofotometrijskim metodama.
Rezultati dobijeni za koncentraciju SH grupa u u škrgama, bubregu i crevu
mrene pokazuju statistički značajno povećanje u letnjoj sezoni u poređenju sa prolećnom
sezonom. Koncentracija vitamina E pokazuje statistički značajno smanjenje u letnjoj
sezoni u odnosu na proleće i ovaj trend zabeležen je u svim ispitivanim tkivima. Naša
studija predstavlja prvu procenu koncentracije vitamina E i SH grupa u škrgama,
bubregu i crevu rečne mrene u srpskom delu Dunava.
Zaključuje se da je sezonska fluktuacija ispitivanih komponenti sistema zaštite
od oksidacionih oštećenja u korelaciji sa sezonskim temperaturnim varijacijama.
PB  - Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju
C3  - Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia
T1  - Koncentracija vitamina E i SH grupa u nekim tkivima rečne mrene Barbus barbus iz reke Dunav
SP  - 75
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5943
ER  - 

@conference{
author = "Radovanović, Tijana and Gavrilović, Branka and Despotović, Svetlana and Gavrić, Jelena and Borković-Mitić, Slavica and Pavlović, Slađan and Predrag, Cakić and Pajović, Snežana and Saičić, Zorica",
year = "2011",
abstract = "U našoj studiji određivali smo sezonski zavisnu promenu u koncentraciji
vitamina E i SH grupa u škrgama, bubregu i crevu rečne mrene (Barbus barbus) iz
Dunava, koja predstavlja bentosnu ribu široke geografske distribucije. Istraživanja su
izvedena u prigradskom području Beograda, između Višnjice i Grocke, u prolećnoj i
letnjoj sezoni. Koncentracije ispitivanih parametara merene su standardnim
spektrofotometrijskim metodama.
Rezultati dobijeni za koncentraciju SH grupa u u škrgama, bubregu i crevu
mrene pokazuju statistički značajno povećanje u letnjoj sezoni u poređenju sa prolećnom
sezonom. Koncentracija vitamina E pokazuje statistički značajno smanjenje u letnjoj
sezoni u odnosu na proleće i ovaj trend zabeležen je u svim ispitivanim tkivima. Naša
studija predstavlja prvu procenu koncentracije vitamina E i SH grupa u škrgama,
bubregu i crevu rečne mrene u srpskom delu Dunava.
Zaključuje se da je sezonska fluktuacija ispitivanih komponenti sistema zaštite
od oksidacionih oštećenja u korelaciji sa sezonskim temperaturnim varijacijama.",
publisher = "Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju",
journal = "Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia",
title = "Koncentracija vitamina E i SH grupa u nekim tkivima rečne mrene Barbus barbus iz reke Dunav",
pages = "75",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5943"
}

Radovanović, T., Gavrilović, B., Despotović, S., Gavrić, J., Borković-Mitić, S., Pavlović, S., Predrag, C., Pajović, S.,& Saičić, Z.. (2011). Koncentracija vitamina E i SH grupa u nekim tkivima rečne mrene Barbus barbus iz reke Dunav. in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia
Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju., 75.
https://hdl.handle.net/21.15107/rcub_ibiss_5943

Radovanović T, Gavrilović B, Despotović S, Gavrić J, Borković-Mitić S, Pavlović S, Predrag C, Pajović S, Saičić Z. Koncentracija vitamina E i SH grupa u nekim tkivima rečne mrene Barbus barbus iz reke Dunav. in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia. 2011;:75.
https://hdl.handle.net/21.15107/rcub_ibiss_5943 .

Radovanović, Tijana, Gavrilović, Branka, Despotović, Svetlana, Gavrić, Jelena, Borković-Mitić, Slavica, Pavlović, Slađan, Predrag, Cakić, Pajović, Snežana, Saičić, Zorica, "Koncentracija vitamina E i SH grupa u nekim tkivima rečne mrene Barbus barbus iz reke Dunav" in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia (2011):75,
https://hdl.handle.net/21.15107/rcub_ibiss_5943 .

TY  - CONF
AU  - Gavrilović, Branka
AU  - Despotović, Svetlana
AU  - Gavrić, Jelena
AU  - Radovanović, Tijana
AU  - Borković-Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Simić, Snežana
AU  - Ognjanović, Branka
AU  - Pajović, Snežana
AU  - Saičić, Zorica
PY  - 2011
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5938
AB  - U našoj studiji istraživali smo promene aktivnosti enzima zaštite od oksidacionih oštećenja: ukupne superoksid-dismutaze (Uk SOD), bakar, cink sadržavajuće superoksid-dismutaze (CuZnSOD), mangan sadržavajuće superoksiddismutaze (MnSOD) i katalaze (CAT) u škrgama i mišiću slatkovodne ribe grgeča (Perca fluviatilis) kao odgovor na cvetanje cijanobakterije Aphanizomenon flos-aquae u Gružanskom jezeru. Takođe, ispitivana je koncentracija ukupnih proteina, kao i elektroforetska analiza proteina i SOD. Svi parametri određivani su tokom dva perioda, pre i za vreme cvetanja. Aktivnosti Uk SOD i MnSOD bile su niže i u škrgama i u mišiću, dok je aktivnost CuZnSOD pokazala niže vrednosti u mišiću za vreme cvetanja u odnosu na period pre cvetanja. Aktivnost CAT bila je značajno veća u oba ispitivana tkiva tokom cvetanja. U mišiću je zabeleženo statistički značajno povećanje koncentracije ukupnih proteina za vreme cvetanja, dok je elektroforetska analiza proteina ukazala na razlike u profilu proteina u škrgama i mišiću između dva ispitivana perioda. Elektroforetski profil enzima SOD pokazao je tipičan distribucioni obrazac SOD izoformi u oba tkiva. Naš rad predstavlja prvu studiju o uticaju cvetanja cijanobakterija na aktivnost enzima zaštite od oksidacionih oštećenja superoksid-dismutaze i katalaze u škrgama i mišiću slatkovodne ribe grgeča (Perca fluviatilis) iz Gružanskog jezera i ukazuje da cvetanje Aphanizomenon flos-aquae indukuje oksidacioni stres u ispitivanim tkivima. Ovo istraživanje daje osnovu za molekularno fiziološki biomonitoring uticaja cijanobakterija na različite slatkovodne organizme.
PB  - Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju
C3  - Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia
T1  - Promene aktivnosti superoksid-dismutaze i katalaze u nekim tkivima slatkovodne ribe grgeča (Perca fluviatilis) kao odgovor na cvetanje cijanobakterija u gružanskom jezeru
SP  - 41
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5938
ER  - 

@conference{
author = "Gavrilović, Branka and Despotović, Svetlana and Gavrić, Jelena and Radovanović, Tijana and Borković-Mitić, Slavica and Pavlović, Slađan and Simić, Snežana and Ognjanović, Branka and Pajović, Snežana and Saičić, Zorica",
year = "2011",
abstract = "U našoj studiji istraživali smo promene aktivnosti enzima zaštite od oksidacionih oštećenja: ukupne superoksid-dismutaze (Uk SOD), bakar, cink sadržavajuće superoksid-dismutaze (CuZnSOD), mangan sadržavajuće superoksiddismutaze (MnSOD) i katalaze (CAT) u škrgama i mišiću slatkovodne ribe grgeča (Perca fluviatilis) kao odgovor na cvetanje cijanobakterije Aphanizomenon flos-aquae u Gružanskom jezeru. Takođe, ispitivana je koncentracija ukupnih proteina, kao i elektroforetska analiza proteina i SOD. Svi parametri određivani su tokom dva perioda, pre i za vreme cvetanja. Aktivnosti Uk SOD i MnSOD bile su niže i u škrgama i u mišiću, dok je aktivnost CuZnSOD pokazala niže vrednosti u mišiću za vreme cvetanja u odnosu na period pre cvetanja. Aktivnost CAT bila je značajno veća u oba ispitivana tkiva tokom cvetanja. U mišiću je zabeleženo statistički značajno povećanje koncentracije ukupnih proteina za vreme cvetanja, dok je elektroforetska analiza proteina ukazala na razlike u profilu proteina u škrgama i mišiću između dva ispitivana perioda. Elektroforetski profil enzima SOD pokazao je tipičan distribucioni obrazac SOD izoformi u oba tkiva. Naš rad predstavlja prvu studiju o uticaju cvetanja cijanobakterija na aktivnost enzima zaštite od oksidacionih oštećenja superoksid-dismutaze i katalaze u škrgama i mišiću slatkovodne ribe grgeča (Perca fluviatilis) iz Gružanskog jezera i ukazuje da cvetanje Aphanizomenon flos-aquae indukuje oksidacioni stres u ispitivanim tkivima. Ovo istraživanje daje osnovu za molekularno fiziološki biomonitoring uticaja cijanobakterija na različite slatkovodne organizme.",
publisher = "Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju",
journal = "Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia",
title = "Promene aktivnosti superoksid-dismutaze i katalaze u nekim tkivima slatkovodne ribe grgeča (Perca fluviatilis) kao odgovor na cvetanje cijanobakterija u gružanskom jezeru",
pages = "41",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5938"
}

Gavrilović, B., Despotović, S., Gavrić, J., Radovanović, T., Borković-Mitić, S., Pavlović, S., Simić, S., Ognjanović, B., Pajović, S.,& Saičić, Z.. (2011). Promene aktivnosti superoksid-dismutaze i katalaze u nekim tkivima slatkovodne ribe grgeča (Perca fluviatilis) kao odgovor na cvetanje cijanobakterija u gružanskom jezeru. in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia
Beograd: Srpsko društvo za mitohondrijalnu i slobodno-radikalsku fiziologiju., 41.
https://hdl.handle.net/21.15107/rcub_ibiss_5938

Gavrilović B, Despotović S, Gavrić J, Radovanović T, Borković-Mitić S, Pavlović S, Simić S, Ognjanović B, Pajović S, Saičić Z. Promene aktivnosti superoksid-dismutaze i katalaze u nekim tkivima slatkovodne ribe grgeča (Perca fluviatilis) kao odgovor na cvetanje cijanobakterija u gružanskom jezeru. in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia. 2011;:41.
https://hdl.handle.net/21.15107/rcub_ibiss_5938 .

Gavrilović, Branka, Despotović, Svetlana, Gavrić, Jelena, Radovanović, Tijana, Borković-Mitić, Slavica, Pavlović, Slađan, Simić, Snežana, Ognjanović, Branka, Pajović, Snežana, Saičić, Zorica, "Promene aktivnosti superoksid-dismutaze i katalaze u nekim tkivima slatkovodne ribe grgeča (Perca fluviatilis) kao odgovor na cvetanje cijanobakterija u gružanskom jezeru" in Knjiga sažetaka: Prvi Kongres Mitohondrije i slobodni radikala - perspektive; 2011 Sep 24; Belgrade, Serbia (2011):41,
https://hdl.handle.net/21.15107/rcub_ibiss_5938 .

TY  - CONF
AU  - Despotović, Svetlana
AU  - Gavrilović, Branka
AU  - Radovanović, Tijana
AU  - Gavrić, Jelena
AU  - Borković-Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Paunović, Momir
AU  - Pajović, Snežana
AU  - Saičić, Zorica
PY  - 2010
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5949
AB  - Data are presented in this study on the tissue glutathione (GSH) content and on the activity on the main enzymes involved in GSH metabolism ( glutathione peroxidase - GSH-Px, glutathione reductase - GR and phase II biotransfor­ mation enzyme glutathione-S-transferase - GST) in the whole body of fresh­ water snail, Viviparus acerosus of two different age groups - young and adults from the Danube River. The obtained results show, that there was no differences in content of GSH in both investigating groups of snails. We observed that the activity of GR was significantly lower in adults in comparison to young groups. The activity of GST was markedly higher in adults in respect to the young snails. Moreover, GSH-Px activity did not change in different age groups, this possible indicating no variation in organic peroxide production and/or metabolism during ageing process. Ageing seems to affect the activity of GSH related enzymes and, in particular, the activities of GR and phase II biotransformation enzyme GST. Our work represents the first study of its kind and these data indicate that, in age­ ing freshwater snails, Viviparus acerosus from the Danube river the increased susceptibility to oxidative stress is partly related in alteration in glutathione me­ tabolism.
PB  - Belgrade: University of Belgrade, Faculty of Biology
C3  - Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia
T1  - Age related differences in glutathione metabolism in freshwater snail, Viviparus acerosus from the Danube river
SP  - 97
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5949
ER  - 

@conference{
author = "Despotović, Svetlana and Gavrilović, Branka and Radovanović, Tijana and Gavrić, Jelena and Borković-Mitić, Slavica and Pavlović, Slađan and Paunović, Momir and Pajović, Snežana and Saičić, Zorica",
year = "2010",
abstract = "Data are presented in this study on the tissue glutathione (GSH) content and on the activity on the main enzymes involved in GSH metabolism ( glutathione peroxidase - GSH-Px, glutathione reductase - GR and phase II biotransfor­ mation enzyme glutathione-S-transferase - GST) in the whole body of fresh­ water snail, Viviparus acerosus of two different age groups - young and adults from the Danube River. The obtained results show, that there was no differences in content of GSH in both investigating groups of snails. We observed that the activity of GR was significantly lower in adults in comparison to young groups. The activity of GST was markedly higher in adults in respect to the young snails. Moreover, GSH-Px activity did not change in different age groups, this possible indicating no variation in organic peroxide production and/or metabolism during ageing process. Ageing seems to affect the activity of GSH related enzymes and, in particular, the activities of GR and phase II biotransformation enzyme GST. Our work represents the first study of its kind and these data indicate that, in age­ ing freshwater snails, Viviparus acerosus from the Danube river the increased susceptibility to oxidative stress is partly related in alteration in glutathione me­ tabolism.",
publisher = "Belgrade: University of Belgrade, Faculty of Biology",
journal = "Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia",
title = "Age related differences in glutathione metabolism in freshwater snail, Viviparus acerosus from the Danube river",
pages = "97",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5949"
}

Despotović, S., Gavrilović, B., Radovanović, T., Gavrić, J., Borković-Mitić, S., Pavlović, S., Paunović, M., Pajović, S.,& Saičić, Z.. (2010). Age related differences in glutathione metabolism in freshwater snail, Viviparus acerosus from the Danube river. in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia
Belgrade: University of Belgrade, Faculty of Biology., 97.
https://hdl.handle.net/21.15107/rcub_ibiss_5949

Despotović S, Gavrilović B, Radovanović T, Gavrić J, Borković-Mitić S, Pavlović S, Paunović M, Pajović S, Saičić Z. Age related differences in glutathione metabolism in freshwater snail, Viviparus acerosus from the Danube river. in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia. 2010;:97.
https://hdl.handle.net/21.15107/rcub_ibiss_5949 .

Despotović, Svetlana, Gavrilović, Branka, Radovanović, Tijana, Gavrić, Jelena, Borković-Mitić, Slavica, Pavlović, Slađan, Paunović, Momir, Pajović, Snežana, Saičić, Zorica, "Age related differences in glutathione metabolism in freshwater snail, Viviparus acerosus from the Danube river" in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia (2010):97,
https://hdl.handle.net/21.15107/rcub_ibiss_5949 .

TY  - CONF
AU  - Gavrilović, Branka
AU  - Despotović, Svetlana
AU  - Radovanović, Tijana
AU  - Gavrić, Jelena
AU  - Borković-Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Ognjanović, Branka
AU  - Pajović, Snežana
AU  - Saičić, Zorica
PY  - 2010
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5946
AB  - We investigated alterations of antioxidant defence system (ADS) in the liver of freshwater fish, European perch (Perea fluviatilis) as response to toxic Apha­ nizomenon flos-aquae bloom in the Gruza Reservoir. Activities of total, manga­ nese, copper zinc containing superoxide dismutase (Tot SOD, Mn SOD, CuZn SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR), phase II biotransformation enzyme glutathione S-transferase (GST), con­ centrations of total glutathione (GSH) and sulphydryl (-SH) groups were mea­ sured before and during bloom period. Histopathological examinations were studied using electron microscopy. Activities of CuZn SOD, CAT and GSH-Px and concentration of -SH groups were significantly lower, while Mn SOD activ­ ity was significantly higher during bloom period. No differences were observed for Tot SOD, GR and GST activities, as well as for GSH concentration. Electron microscopy showed alterations in hepatocytes, which results in damage of cells. Our work represents the first study of its kind and suggest on influence of toxic Aphanizomenon flos-aquae bloom in the Gruza Reservoir on ADS and on histo­ pathological changes in the liver of Perea fiuviatilis indicating on necrotic and apopototic damages of hepatocytes.
PB  - Belgrade: University of Belgrade, Faculty of Biology
C3  - Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia
T1  - Antioxidant defence responses to toxic cyanobacterial bloom in the liver of freshwater fish, Perca fluviatilis from the Gruža reservoir
SP  - 112
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5946
ER  - 

@conference{
author = "Gavrilović, Branka and Despotović, Svetlana and Radovanović, Tijana and Gavrić, Jelena and Borković-Mitić, Slavica and Pavlović, Slađan and Ognjanović, Branka and Pajović, Snežana and Saičić, Zorica",
year = "2010",
abstract = "We investigated alterations of antioxidant defence system (ADS) in the liver of freshwater fish, European perch (Perea fluviatilis) as response to toxic Apha­ nizomenon flos-aquae bloom in the Gruza Reservoir. Activities of total, manga­ nese, copper zinc containing superoxide dismutase (Tot SOD, Mn SOD, CuZn SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR), phase II biotransformation enzyme glutathione S-transferase (GST), con­ centrations of total glutathione (GSH) and sulphydryl (-SH) groups were mea­ sured before and during bloom period. Histopathological examinations were studied using electron microscopy. Activities of CuZn SOD, CAT and GSH-Px and concentration of -SH groups were significantly lower, while Mn SOD activ­ ity was significantly higher during bloom period. No differences were observed for Tot SOD, GR and GST activities, as well as for GSH concentration. Electron microscopy showed alterations in hepatocytes, which results in damage of cells. Our work represents the first study of its kind and suggest on influence of toxic Aphanizomenon flos-aquae bloom in the Gruza Reservoir on ADS and on histo­ pathological changes in the liver of Perea fiuviatilis indicating on necrotic and apopototic damages of hepatocytes.",
publisher = "Belgrade: University of Belgrade, Faculty of Biology",
journal = "Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia",
title = "Antioxidant defence responses to toxic cyanobacterial bloom in the liver of freshwater fish, Perca fluviatilis from the Gruža reservoir",
pages = "112",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5946"
}

Gavrilović, B., Despotović, S., Radovanović, T., Gavrić, J., Borković-Mitić, S., Pavlović, S., Ognjanović, B., Pajović, S.,& Saičić, Z.. (2010). Antioxidant defence responses to toxic cyanobacterial bloom in the liver of freshwater fish, Perca fluviatilis from the Gruža reservoir. in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia
Belgrade: University of Belgrade, Faculty of Biology., 112.
https://hdl.handle.net/21.15107/rcub_ibiss_5946

Gavrilović B, Despotović S, Radovanović T, Gavrić J, Borković-Mitić S, Pavlović S, Ognjanović B, Pajović S, Saičić Z. Antioxidant defence responses to toxic cyanobacterial bloom in the liver of freshwater fish, Perca fluviatilis from the Gruža reservoir. in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia. 2010;:112.
https://hdl.handle.net/21.15107/rcub_ibiss_5946 .

Gavrilović, Branka, Despotović, Svetlana, Radovanović, Tijana, Gavrić, Jelena, Borković-Mitić, Slavica, Pavlović, Slađan, Ognjanović, Branka, Pajović, Snežana, Saičić, Zorica, "Antioxidant defence responses to toxic cyanobacterial bloom in the liver of freshwater fish, Perca fluviatilis from the Gruža reservoir" in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia (2010):112,
https://hdl.handle.net/21.15107/rcub_ibiss_5946 .

TY  - CONF
AU  - Borković-Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Radovanović, Tijana
AU  - Gavrilović, Branka
AU  - Despotović, Svetlana
AU  - Gavrić, Jelena
AU  - Paunović, Momir
AU  - Pajović, Snežana
AU  - Saičić, Zorica
PY  - 2010
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5945
AB  - In the present study we have used the activity of aantioxidative defence enzymes: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and the activity of glutathione S-transferase (GST), an enzyme of the phase II biotransformation process to evaluate their utility as biological toll for pollution monitoring in the Sava River. We also determined total protein content, as well as protein and SOD electrophoretic profiles in the digestive gland and the gills of the freshwater bivalve anodonta woodiana. Obtained results indicate a significant influence of tissue specifity of the all investigated enzyme activities. The activities of SOD, CAT, GSH-Px and phase II biotransformation enzyme GST were significantly higher in the digestive gland in respect to the gills, whereas GR activity exhibited higher levels in the gills. This was most likely a reflection of different metabolic activities and different responses to environmental conditions of the examined tissues. Our study also suggest, that the variation of SOD expression pattern in Anodonta woodiana could be used as a tool for the environmental monitoring. Our wo bivalve Anodonta woodiana friom the Sava Riverrk represents a first study of this kind and showed that the antioxidant defence enzymes can be considered as a potential biomarkers of the freshwater
PB  - Belgrade: University of Belgrade, Faculty of Biology
C3  - Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia
T1  - Antioxidant defence enzyme activities in some tissues of the freshwater bivalve Anodonta woodiana from the Sava river
SP  - 95
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5945
ER  - 

@conference{
author = "Borković-Mitić, Slavica and Pavlović, Slađan and Radovanović, Tijana and Gavrilović, Branka and Despotović, Svetlana and Gavrić, Jelena and Paunović, Momir and Pajović, Snežana and Saičić, Zorica",
year = "2010",
abstract = "In the present study we have used the activity of aantioxidative defence enzymes: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and the activity of glutathione S-transferase (GST), an enzyme of the phase II biotransformation process to evaluate their utility as biological toll for pollution monitoring in the Sava River. We also determined total protein content, as well as protein and SOD electrophoretic profiles in the digestive gland and the gills of the freshwater bivalve anodonta woodiana. Obtained results indicate a significant influence of tissue specifity of the all investigated enzyme activities. The activities of SOD, CAT, GSH-Px and phase II biotransformation enzyme GST were significantly higher in the digestive gland in respect to the gills, whereas GR activity exhibited higher levels in the gills. This was most likely a reflection of different metabolic activities and different responses to environmental conditions of the examined tissues. Our study also suggest, that the variation of SOD expression pattern in Anodonta woodiana could be used as a tool for the environmental monitoring. Our wo bivalve Anodonta woodiana friom the Sava Riverrk represents a first study of this kind and showed that the antioxidant defence enzymes can be considered as a potential biomarkers of the freshwater",
publisher = "Belgrade: University of Belgrade, Faculty of Biology",
journal = "Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia",
title = "Antioxidant defence enzyme activities in some tissues of the freshwater bivalve Anodonta woodiana from the Sava river",
pages = "95",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5945"
}

Borković-Mitić, S., Pavlović, S., Radovanović, T., Gavrilović, B., Despotović, S., Gavrić, J., Paunović, M., Pajović, S.,& Saičić, Z.. (2010). Antioxidant defence enzyme activities in some tissues of the freshwater bivalve Anodonta woodiana from the Sava river. in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia
Belgrade: University of Belgrade, Faculty of Biology., 95.
https://hdl.handle.net/21.15107/rcub_ibiss_5945

Borković-Mitić S, Pavlović S, Radovanović T, Gavrilović B, Despotović S, Gavrić J, Paunović M, Pajović S, Saičić Z. Antioxidant defence enzyme activities in some tissues of the freshwater bivalve Anodonta woodiana from the Sava river. in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia. 2010;:95.
https://hdl.handle.net/21.15107/rcub_ibiss_5945 .

Borković-Mitić, Slavica, Pavlović, Slađan, Radovanović, Tijana, Gavrilović, Branka, Despotović, Svetlana, Gavrić, Jelena, Paunović, Momir, Pajović, Snežana, Saičić, Zorica, "Antioxidant defence enzyme activities in some tissues of the freshwater bivalve Anodonta woodiana from the Sava river" in Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia (2010):95,
https://hdl.handle.net/21.15107/rcub_ibiss_5945 .

TY  - JOUR
AU  - Gavrilović, Branka
AU  - Borković Mitić, Slavica
AU  - Radovanović, Tijana
AU  - Pavlović, Slađan
AU  - Stojanović, Bojana D.
AU  - Paunović, Momir
AU  - Cakić, Predrag D.
AU  - Radojičić, Ratko M.
AU  - Pajović, Snežana B.
AU  - Saičić, Zorica
PY  - 2007
PY  - 2007
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/158
AB  - We investigated activities of glutathione peroxidase (GSH-Px), glutathione reductase (GR), and the phase II biotransformation enzyme glutathione-S-transferase (GST) in the foot of three freshwater mussel species: Unio pictorum (Up), Unio tumidus (Ut), and Sinanodonta woodiana (Sw) from the Sava River. Specific and total GSH-Px activity was lower in Sw than in Up and Ut. Total GR activity was higher in Up than in Sw. Specific GST activity was higher in Up than in Ut. Total GST activity was higher in Up than in Ut and Sw. Electrophoretic analysis of proteins shows species specifities between the investigated mussel species. Our study represents the first comprehensive report of the investigated glutathione-dependent enzyme activities in the foot of three freshwater mussel species from the Sava River, Serbia. .
AB  - Određivali smo aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u stopalu tri vrste slatkovodnih školjki: Unio pictorum (Up), Unio tumidus (Ut) i Sinanodonta woodiana (Sw) iz reke Save. Specifična i ukupna aktivnost GSH-Px je bila manja kod Sw u odnosu na Up i Ut. Ukupna aktivnost GR je bila veća kod Up u poređenju sa Sw. Specifična aktivnost GST je bila veća kod Up u odnosu na Ut. Ukupna aktivnost GST je bila veća kod Up u poređenju sa Ut i Sw. Elektroforetska analiza proteina pokazuje specifičnost za vrstu kod ispitivanih školjki. Naša studija predstavlja prvi obiman izveštaj o aktivnosti glutation zavisnih enzima u stopalima tri vrste slatkovodnih školjaka iz reke Save. .
PB  - Serbian Biological Society
T2  - Archives of Biological Sciences
T1  - Aktivnost glutation zavisnih enzima u stopalu tri vrste slatkovodnih školjki iz reke Save, Srbija
T1  - Glutathione dependent enzyme activities in the foot of three freshwater mussel species in the Sava river, Serbia
IS  - 3
VL  - 59
DO  - 10.2298/ABS0703169P
SP  - 169
EP  - 175
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_158
ER  - 

@article{
author = "Gavrilović, Branka and Borković Mitić, Slavica and Radovanović, Tijana and Pavlović, Slađan and Stojanović, Bojana D. and Paunović, Momir and Cakić, Predrag D. and Radojičić, Ratko M. and Pajović, Snežana B. and Saičić, Zorica",
year = "2007, 2007",
abstract = "We investigated activities of glutathione peroxidase (GSH-Px), glutathione reductase (GR), and the phase II biotransformation enzyme glutathione-S-transferase (GST) in the foot of three freshwater mussel species: Unio pictorum (Up), Unio tumidus (Ut), and Sinanodonta woodiana (Sw) from the Sava River. Specific and total GSH-Px activity was lower in Sw than in Up and Ut. Total GR activity was higher in Up than in Sw. Specific GST activity was higher in Up than in Ut. Total GST activity was higher in Up than in Ut and Sw. Electrophoretic analysis of proteins shows species specifities between the investigated mussel species. Our study represents the first comprehensive report of the investigated glutathione-dependent enzyme activities in the foot of three freshwater mussel species from the Sava River, Serbia. ., Određivali smo aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u stopalu tri vrste slatkovodnih školjki: Unio pictorum (Up), Unio tumidus (Ut) i Sinanodonta woodiana (Sw) iz reke Save. Specifična i ukupna aktivnost GSH-Px je bila manja kod Sw u odnosu na Up i Ut. Ukupna aktivnost GR je bila veća kod Up u poređenju sa Sw. Specifična aktivnost GST je bila veća kod Up u odnosu na Ut. Ukupna aktivnost GST je bila veća kod Up u poređenju sa Ut i Sw. Elektroforetska analiza proteina pokazuje specifičnost za vrstu kod ispitivanih školjki. Naša studija predstavlja prvi obiman izveštaj o aktivnosti glutation zavisnih enzima u stopalima tri vrste slatkovodnih školjaka iz reke Save. .",
publisher = "Serbian Biological Society",
journal = "Archives of Biological Sciences",
title = "Aktivnost glutation zavisnih enzima u stopalu tri vrste slatkovodnih školjki iz reke Save, Srbija, Glutathione dependent enzyme activities in the foot of three freshwater mussel species in the Sava river, Serbia",
number = "3",
volume = "59",
doi = "10.2298/ABS0703169P",
pages = "169-175",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_158"
}

Gavrilović, B., Borković Mitić, S., Radovanović, T., Pavlović, S., Stojanović, B. D., Paunović, M., Cakić, P. D., Radojičić, R. M., Pajović, S. B.,& Saičić, Z.. (2007). Aktivnost glutation zavisnih enzima u stopalu tri vrste slatkovodnih školjki iz reke Save, Srbija. in Archives of Biological Sciences
Serbian Biological Society., 59(3), 169-175.
https://doi.org/10.2298/ABS0703169P
https://hdl.handle.net/21.15107/rcub_ibiss_158

Gavrilović B, Borković Mitić S, Radovanović T, Pavlović S, Stojanović BD, Paunović M, Cakić PD, Radojičić RM, Pajović SB, Saičić Z. Aktivnost glutation zavisnih enzima u stopalu tri vrste slatkovodnih školjki iz reke Save, Srbija. in Archives of Biological Sciences. 2007;59(3):169-175.
doi:10.2298/ABS0703169P
https://hdl.handle.net/21.15107/rcub_ibiss_158 .

Gavrilović, Branka, Borković Mitić, Slavica, Radovanović, Tijana, Pavlović, Slađan, Stojanović, Bojana D., Paunović, Momir, Cakić, Predrag D., Radojičić, Ratko M., Pajović, Snežana B., Saičić, Zorica, "Aktivnost glutation zavisnih enzima u stopalu tri vrste slatkovodnih školjki iz reke Save, Srbija" in Archives of Biological Sciences, 59, no. 3 (2007):169-175,
https://doi.org/10.2298/ABS0703169P .,
https://hdl.handle.net/21.15107/rcub_ibiss_158 .

TY  - JOUR
AU  - Gavrilović, Branka
AU  - Borković Mitić, Slavica
AU  - Radovanović, Tijana
AU  - Pavlović, Slađan
AU  - Stojanović, Bojana D.
AU  - Paunović, Momir
AU  - Cakić, Predrag D.
AU  - Pajović, Snežana B.
AU  - Saičić, Zorica
PY  - 2007
PY  - 2007
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/152
PB  - Serbian Biological Society
T2  - Archives of Biological Sciences
T1  - Activities of superoxide dismutase and catalase in the foot of three freshwater mussel species
IS  - 2
VL  - 59
DO  - 10.2298/ABS0702001P
SP  - 17
EP  - 19
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_152
ER  - 

@article{
author = "Gavrilović, Branka and Borković Mitić, Slavica and Radovanović, Tijana and Pavlović, Slađan and Stojanović, Bojana D. and Paunović, Momir and Cakić, Predrag D. and Pajović, Snežana B. and Saičić, Zorica",
year = "2007, 2007",
publisher = "Serbian Biological Society",
journal = "Archives of Biological Sciences",
title = "Activities of superoxide dismutase and catalase in the foot of three freshwater mussel species",
number = "2",
volume = "59",
doi = "10.2298/ABS0702001P",
pages = "17-19",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_152"
}

Gavrilović, B., Borković Mitić, S., Radovanović, T., Pavlović, S., Stojanović, B. D., Paunović, M., Cakić, P. D., Pajović, S. B.,& Saičić, Z.. (2007). Activities of superoxide dismutase and catalase in the foot of three freshwater mussel species. in Archives of Biological Sciences
Serbian Biological Society., 59(2), 17-19.
https://doi.org/10.2298/ABS0702001P
https://hdl.handle.net/21.15107/rcub_ibiss_152

Gavrilović B, Borković Mitić S, Radovanović T, Pavlović S, Stojanović BD, Paunović M, Cakić PD, Pajović SB, Saičić Z. Activities of superoxide dismutase and catalase in the foot of three freshwater mussel species. in Archives of Biological Sciences. 2007;59(2):17-19.
doi:10.2298/ABS0702001P
https://hdl.handle.net/21.15107/rcub_ibiss_152 .

Gavrilović, Branka, Borković Mitić, Slavica, Radovanović, Tijana, Pavlović, Slađan, Stojanović, Bojana D., Paunović, Momir, Cakić, Predrag D., Pajović, Snežana B., Saičić, Zorica, "Activities of superoxide dismutase and catalase in the foot of three freshwater mussel species" in Archives of Biological Sciences, 59, no. 2 (2007):17-19,
https://doi.org/10.2298/ABS0702001P .,
https://hdl.handle.net/21.15107/rcub_ibiss_152 .

TY  - JOUR
AU  - Despotović, Svetlana
AU  - Gavrilović, Branka
AU  - Radovanović, Tijana
AU  - Borković Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Milošević, S.M.
AU  - Đikanović, Vesna
AU  - Cakić, Predrag D.
AU  - Pajović, Snežana B.
AU  - Saičić, Zorica
PY  - 2007
PY  - 2007
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/174
PB  - Belgrade: Serbian Biological Society
T2  - Archives of Biological Sciences
T1  - Glutathione redox status in some tissues and the intestinal parasite Pomphorhynchus laevis (Acanthocephala) from barbel (Barbus barbus)(Pisces) from the Danube river
IS  - 4
VL  - 59
DO  - 10.2298/ABS0704057D
SP  - 57
EP  - 58
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_174
ER  - 

@article{
author = "Despotović, Svetlana and Gavrilović, Branka and Radovanović, Tijana and Borković Mitić, Slavica and Pavlović, Slađan and Milošević, S.M. and Đikanović, Vesna and Cakić, Predrag D. and Pajović, Snežana B. and Saičić, Zorica",
year = "2007, 2007",
publisher = "Belgrade: Serbian Biological Society",
journal = "Archives of Biological Sciences",
title = "Glutathione redox status in some tissues and the intestinal parasite Pomphorhynchus laevis (Acanthocephala) from barbel (Barbus barbus)(Pisces) from the Danube river",
number = "4",
volume = "59",
doi = "10.2298/ABS0704057D",
pages = "57-58",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_174"
}

Despotović, S., Gavrilović, B., Radovanović, T., Borković Mitić, S., Pavlović, S., Milošević, S.M., Đikanović, V., Cakić, P. D., Pajović, S. B.,& Saičić, Z.. (2007). Glutathione redox status in some tissues and the intestinal parasite Pomphorhynchus laevis (Acanthocephala) from barbel (Barbus barbus)(Pisces) from the Danube river. in Archives of Biological Sciences
Belgrade: Serbian Biological Society., 59(4), 57-58.
https://doi.org/10.2298/ABS0704057D
https://hdl.handle.net/21.15107/rcub_ibiss_174

Despotović S, Gavrilović B, Radovanović T, Borković Mitić S, Pavlović S, Milošević S, Đikanović V, Cakić PD, Pajović SB, Saičić Z. Glutathione redox status in some tissues and the intestinal parasite Pomphorhynchus laevis (Acanthocephala) from barbel (Barbus barbus)(Pisces) from the Danube river. in Archives of Biological Sciences. 2007;59(4):57-58.
doi:10.2298/ABS0704057D
https://hdl.handle.net/21.15107/rcub_ibiss_174 .

Despotović, Svetlana, Gavrilović, Branka, Radovanović, Tijana, Borković Mitić, Slavica, Pavlović, Slađan, Milošević, S.M., Đikanović, Vesna, Cakić, Predrag D., Pajović, Snežana B., Saičić, Zorica, "Glutathione redox status in some tissues and the intestinal parasite Pomphorhynchus laevis (Acanthocephala) from barbel (Barbus barbus)(Pisces) from the Danube river" in Archives of Biological Sciences, 59, no. 4 (2007):57-58,
https://doi.org/10.2298/ABS0704057D .,
https://hdl.handle.net/21.15107/rcub_ibiss_174 .

TY  - JOUR
AU  - Borković Mitić, Slavica
AU  - Pavlović, Slađan
AU  - Radovanović, Tijana
AU  - Milošević, Slaviša M.
AU  - Pajović, Snežana B.
AU  - Žikić, Radoslav V.
AU  - Petrović, Vojislav M.
AU  - Saičić, Zorica
PY  - 2006
PY  - 2006
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/322
AB  - We investigated the activities of glutathione peroxidase (GSH-Px) glutathione reductase (GR) and phase II biotransformation enzyme glutathione-S-transferase (GST) in the hepatopancreas, the gills and muscle of Noble crayfish (Astacus astacus-AST), Stone crayfish (Austropotamobius torrentium-AUS) and Spynicheek crayfish (Orconectes limosus-ORC) from the South Morava River, Krajkovačka River and Serbian part of the Danube. Specific GSH-Px activity was lower in the hepatopancreas of AUS than in ORC and in the muscle of AST than in AUS and ORC. We obtained differences of total GSH-Px activity in the muscle between AST and AUS and between AST and ORC. Specific and total GR activity was higher in the hepatopancreas of AST than in other species. Specific and total activity of GR in the gills and in the muscle of crayfish species was higher in AUS then in AST and ORC. The specific and total GST activity was lower in the hepatopancreas of AST and ORC than in AUS. Specific and total GST activity in the gills was higher in AUS than in AST. The lowest specific and total GST activity was detected in the muscle of ORC compared to the AST and AUS. Our results show that specific and total enzyme activities of GSH-Px, GR and GST have species and tissue specifics between crayfish species and represent biomarkers of environmental influences on these organisms.
AB  - Određivali smo aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u hepatopankreasu, škrgama i mišiću rečnog raka (Astacus astacus-AST), raka kamenjara (Austropotamobius torrentium-AUS) i američkog raka (Orconectes limosus-ORC) iz Južne Morave, Krajkovačke reke i Dunava. Specifična aktivnost GSH-Px je manja u hepatopankreasu kod AUS nego kod ORC, kao i u mišiću AST u poređenju sa AUS i ORC. Postoji razlika u aktivnosti između ukupne GSH-Px u mišiću kod AST i AUS, kao i između AST i ORC. Specifična i totalna aktivnost GR je veća u hepatopankreasu kod AST nego kod druge dve vrste, dok je u škrgama i mišiću rakova veća kod AUS nego kod AST i ORC. Specifična i totalna aktivnost GST je manja u hepatopankreasu kod AST i ORC u poređenju sa AUS, a u škrgama je veća kod AUS nego kod AST. Najmanja specifična i totalna GST aktivnost je u mišiću kod ORC u poređenju sa AST i AUS. Specifična i ukupna aktivnost GSH-Px, GR i GST pokazuje veliku specifičnost za vrstu i tkivo između ispitivanih vrsta rakova i predstavlja biomarker uticaja sredine na ove organizme.
T2  - Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica
T1  - Aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u tkivima nekih slatkovodnih rakova
T1  - Glutathione peroxidase (GSH-Px), glutathione reductase (GR) and phase II biotransformation enzyme glutathione-S-transferase (GST) activities in tissues of some freshwater crayfish species
IS  - 3
VL  - 42
SP  - 211
EP  - 217
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_322
ER  - 

@article{
author = "Borković Mitić, Slavica and Pavlović, Slađan and Radovanović, Tijana and Milošević, Slaviša M. and Pajović, Snežana B. and Žikić, Radoslav V. and Petrović, Vojislav M. and Saičić, Zorica",
year = "2006, 2006",
abstract = "We investigated the activities of glutathione peroxidase (GSH-Px) glutathione reductase (GR) and phase II biotransformation enzyme glutathione-S-transferase (GST) in the hepatopancreas, the gills and muscle of Noble crayfish (Astacus astacus-AST), Stone crayfish (Austropotamobius torrentium-AUS) and Spynicheek crayfish (Orconectes limosus-ORC) from the South Morava River, Krajkovačka River and Serbian part of the Danube. Specific GSH-Px activity was lower in the hepatopancreas of AUS than in ORC and in the muscle of AST than in AUS and ORC. We obtained differences of total GSH-Px activity in the muscle between AST and AUS and between AST and ORC. Specific and total GR activity was higher in the hepatopancreas of AST than in other species. Specific and total activity of GR in the gills and in the muscle of crayfish species was higher in AUS then in AST and ORC. The specific and total GST activity was lower in the hepatopancreas of AST and ORC than in AUS. Specific and total GST activity in the gills was higher in AUS than in AST. The lowest specific and total GST activity was detected in the muscle of ORC compared to the AST and AUS. Our results show that specific and total enzyme activities of GSH-Px, GR and GST have species and tissue specifics between crayfish species and represent biomarkers of environmental influences on these organisms., Određivali smo aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u hepatopankreasu, škrgama i mišiću rečnog raka (Astacus astacus-AST), raka kamenjara (Austropotamobius torrentium-AUS) i američkog raka (Orconectes limosus-ORC) iz Južne Morave, Krajkovačke reke i Dunava. Specifična aktivnost GSH-Px je manja u hepatopankreasu kod AUS nego kod ORC, kao i u mišiću AST u poređenju sa AUS i ORC. Postoji razlika u aktivnosti između ukupne GSH-Px u mišiću kod AST i AUS, kao i između AST i ORC. Specifična i totalna aktivnost GR je veća u hepatopankreasu kod AST nego kod druge dve vrste, dok je u škrgama i mišiću rakova veća kod AUS nego kod AST i ORC. Specifična i totalna aktivnost GST je manja u hepatopankreasu kod AST i ORC u poređenju sa AUS, a u škrgama je veća kod AUS nego kod AST. Najmanja specifična i totalna GST aktivnost je u mišiću kod ORC u poređenju sa AST i AUS. Specifična i ukupna aktivnost GSH-Px, GR i GST pokazuje veliku specifičnost za vrstu i tkivo između ispitivanih vrsta rakova i predstavlja biomarker uticaja sredine na ove organizme.",
journal = "Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica",
title = "Aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u tkivima nekih slatkovodnih rakova, Glutathione peroxidase (GSH-Px), glutathione reductase (GR) and phase II biotransformation enzyme glutathione-S-transferase (GST) activities in tissues of some freshwater crayfish species",
number = "3",
volume = "42",
pages = "211-217",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_322"
}

Borković Mitić, S., Pavlović, S., Radovanović, T., Milošević, S. M., Pajović, S. B., Žikić, R. V., Petrović, V. M.,& Saičić, Z.. (2006). Aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u tkivima nekih slatkovodnih rakova. in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica, 42(3), 211-217.
https://hdl.handle.net/21.15107/rcub_ibiss_322

Borković Mitić S, Pavlović S, Radovanović T, Milošević SM, Pajović SB, Žikić RV, Petrović VM, Saičić Z. Aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u tkivima nekih slatkovodnih rakova. in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica. 2006;42(3):211-217.
https://hdl.handle.net/21.15107/rcub_ibiss_322 .

Borković Mitić, Slavica, Pavlović, Slađan, Radovanović, Tijana, Milošević, Slaviša M., Pajović, Snežana B., Žikić, Radoslav V., Petrović, Vojislav M., Saičić, Zorica, "Aktivnost glutation-peroksidaze (GSH-Px), glutation-reduktaze (GR) i enzima faze II biotransformacije glutation-S-transferaze (GST) u tkivima nekih slatkovodnih rakova" in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica, 42, no. 3 (2006):211-217,
https://hdl.handle.net/21.15107/rcub_ibiss_322 .