TY  - JOUR
AU  - Milic, Sonja
AU  - Pristov, Jelena Bogdanovic
AU  - Mutavdzic, Dragosav
AU  - Savic, Aleksandar
AU  - Spasić, Mihajlo
AU  - Spasojevic, Ivan
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1971
AB  - Herein we compared antioxidative activities (AA) of 25 free L-amino
   acids (FAA) against Fenton system-mediated hydroxyl radical (HO center
   dot) production in aqueous solution, and examined the relation between
   AA and a set of physicochemical properties. The tank order according -to
   AA was: Tip > notleucine > Phe, Lett > Ile > His
   >3,4-dihydrOxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydtoxyproline
   > alpha-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp.
   Sulfur-containing FAA generated different secondary reactive products,
   which were discriminated by the means of electron paramagnetic resonance
   spin-trapping spectroscopy. AA showed a general positive correlation
   with hydrophobicity. However, when taken separately, uncharged FAA
   exhibited strong positive correlation of AA with hydrophobicity whereas
   charged FAA showed negative or no significant correlation depending on
   the scale applied. A general strong negative correlation was found
   between AA and polarity. Steric parameters and hydration numbers
   correlated positively with AA of rtoripolar side-chain FAA. In addition)
   a decrease of temperature which promotes hydrophobic hydration resulted
   in increased AA. This implies that HO-provoked oxidation of FAA is
   strongly affected by hydrophobic hydration. Our findings are important
   for the understanding of oxidation processes in natural and waste
   waters.
T2  - Environmental Science & Technology
T1  - The Relationship of Physicochemical Properties to the Antioxidative
 Activity of Free Amino Acids in Fenton System
IS  - 7
VL  - 49
DO  - 10.1021/es5053396
SP  - 4245
EP  - 4254
ER  - 

@article{
author = "Milic, Sonja and Pristov, Jelena Bogdanovic and Mutavdzic, Dragosav and Savic, Aleksandar and Spasić, Mihajlo and Spasojevic, Ivan",
year = "2015",
abstract = "Herein we compared antioxidative activities (AA) of 25 free L-amino
   acids (FAA) against Fenton system-mediated hydroxyl radical (HO center
   dot) production in aqueous solution, and examined the relation between
   AA and a set of physicochemical properties. The tank order according -to
   AA was: Tip > notleucine > Phe, Lett > Ile > His
   >3,4-dihydrOxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydtoxyproline
   > alpha-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp.
   Sulfur-containing FAA generated different secondary reactive products,
   which were discriminated by the means of electron paramagnetic resonance
   spin-trapping spectroscopy. AA showed a general positive correlation
   with hydrophobicity. However, when taken separately, uncharged FAA
   exhibited strong positive correlation of AA with hydrophobicity whereas
   charged FAA showed negative or no significant correlation depending on
   the scale applied. A general strong negative correlation was found
   between AA and polarity. Steric parameters and hydration numbers
   correlated positively with AA of rtoripolar side-chain FAA. In addition)
   a decrease of temperature which promotes hydrophobic hydration resulted
   in increased AA. This implies that HO-provoked oxidation of FAA is
   strongly affected by hydrophobic hydration. Our findings are important
   for the understanding of oxidation processes in natural and waste
   waters.",
journal = "Environmental Science & Technology",
title = "The Relationship of Physicochemical Properties to the Antioxidative
 Activity of Free Amino Acids in Fenton System",
number = "7",
volume = "49",
doi = "10.1021/es5053396",
pages = "4245-4254"
}

Milic, S., Pristov, J. B., Mutavdzic, D., Savic, A., Spasić, M.,& Spasojevic, I.. (2015). The Relationship of Physicochemical Properties to the Antioxidative
 Activity of Free Amino Acids in Fenton System. in Environmental Science & Technology, 49(7), 4245-4254.
https://doi.org/10.1021/es5053396

Milic S, Pristov JB, Mutavdzic D, Savic A, Spasić M, Spasojevic I. The Relationship of Physicochemical Properties to the Antioxidative
 Activity of Free Amino Acids in Fenton System. in Environmental Science & Technology. 2015;49(7):4245-4254.
doi:10.1021/es5053396 .

Milic, Sonja, Pristov, Jelena Bogdanovic, Mutavdzic, Dragosav, Savic, Aleksandar, Spasić, Mihajlo, Spasojevic, Ivan, "The Relationship of Physicochemical Properties to the Antioxidative
 Activity of Free Amino Acids in Fenton System" in Environmental Science & Technology, 49, no. 7 (2015):4245-4254,
https://doi.org/10.1021/es5053396 . .