TY  - JOUR
AU  - Krizak, Strahinja
AU  - Nikoic, Ljiljana
AU  - Stanic, Marina
AU  - Zizic, Milan
AU  - Zakrzewska, Joanna
AU  - Zivic, Miroslav
AU  - Todorović, Nataša
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1977
AB  - We describe here whole-cell currents of droplets prepared from the
   apical region of growing Phycomyces blakesleeanus sporangiophores.
   Whole-cell current recordings revealed the osmotically activated,
   outwardly rectifying, fast inactivating instantaneous current (ORIC)
   with biophysical properties closely resembling volume-regulated anionic
   current (VRAC). ORIC is activated under conditions of osmotically
   induced swelling and shows strong selectivity for anions over cations.
   In addition, ORIC shows voltage and time-dependent inactivation at
   positive potentials and recovery from inactivation at negative
   potentials. ORIC is blocked by anthracene-9-carboxylic acid, an anion
   channel blocker, in a voltage-dependent manner. This is the first report
   of the presence of VRAC-like current in an organism outside the chordate
   lineage. (C) 2015 Institut Pasteur. Published by Elsevier Masson SAS.
   All rights reserved.
T2  - Research in Microbiology
T1  - Osmotic swelling activates a novel anionic current with VRAC-like
 properties in a cytoplasmic droplet membrane from Phycomyces
 blakesleeanus sporangiophores
IS  - 3
VL  - 166
DO  - 10.1016/j.resmic.2015.02.004
SP  - 162
EP  - 173
ER  - 

@article{
author = "Krizak, Strahinja and Nikoic, Ljiljana and Stanic, Marina and Zizic, Milan and Zakrzewska, Joanna and Zivic, Miroslav and Todorović, Nataša",
year = "2015",
abstract = "We describe here whole-cell currents of droplets prepared from the
   apical region of growing Phycomyces blakesleeanus sporangiophores.
   Whole-cell current recordings revealed the osmotically activated,
   outwardly rectifying, fast inactivating instantaneous current (ORIC)
   with biophysical properties closely resembling volume-regulated anionic
   current (VRAC). ORIC is activated under conditions of osmotically
   induced swelling and shows strong selectivity for anions over cations.
   In addition, ORIC shows voltage and time-dependent inactivation at
   positive potentials and recovery from inactivation at negative
   potentials. ORIC is blocked by anthracene-9-carboxylic acid, an anion
   channel blocker, in a voltage-dependent manner. This is the first report
   of the presence of VRAC-like current in an organism outside the chordate
   lineage. (C) 2015 Institut Pasteur. Published by Elsevier Masson SAS.
   All rights reserved.",
journal = "Research in Microbiology",
title = "Osmotic swelling activates a novel anionic current with VRAC-like
 properties in a cytoplasmic droplet membrane from Phycomyces
 blakesleeanus sporangiophores",
number = "3",
volume = "166",
doi = "10.1016/j.resmic.2015.02.004",
pages = "162-173"
}

Krizak, S., Nikoic, L., Stanic, M., Zizic, M., Zakrzewska, J., Zivic, M.,& Todorović, N.. (2015). Osmotic swelling activates a novel anionic current with VRAC-like
 properties in a cytoplasmic droplet membrane from Phycomyces
 blakesleeanus sporangiophores. in Research in Microbiology, 166(3), 162-173.
https://doi.org/10.1016/j.resmic.2015.02.004

Krizak S, Nikoic L, Stanic M, Zizic M, Zakrzewska J, Zivic M, Todorović N. Osmotic swelling activates a novel anionic current with VRAC-like
 properties in a cytoplasmic droplet membrane from Phycomyces
 blakesleeanus sporangiophores. in Research in Microbiology. 2015;166(3):162-173.
doi:10.1016/j.resmic.2015.02.004 .

Krizak, Strahinja, Nikoic, Ljiljana, Stanic, Marina, Zizic, Milan, Zakrzewska, Joanna, Zivic, Miroslav, Todorović, Nataša, "Osmotic swelling activates a novel anionic current with VRAC-like
 properties in a cytoplasmic droplet membrane from Phycomyces
 blakesleeanus sporangiophores" in Research in Microbiology, 166, no. 3 (2015):162-173,
https://doi.org/10.1016/j.resmic.2015.02.004 . .