TY  - JOUR
AU  - Glamočlija, Jasmina
AU  - Marin, Petar D.
AU  - Brkić, Dejan D.
AU  - Soković, Marina
AU  - Vukojević, Jelena B.
AU  - Jovanović, Dragutin
AU  - Bulajić, Nina
AU  - Kataranovski, Dragan S.
PY  - 2007
PY  - 2007
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/540
AB  - The in vivo evaluation of antifungal activity of the Lavandula angustifolia essential oil was made on two-month old male Wistar rats. We examined the therapeutic potency against experimentally induced dermatomycoses in rats using the most frequent dermatomycetes, Trichophyton mentagrophytes. The therapeutic efficacy of 1% solution of essential oil as well as commercial preparation-bifonazole, was evaluated. During the 13-day observation period the oil-treated animals were cured completely.
AB  - Infekcije ljudi uzrokovane gljivama su u znatnom porastu u poslednjih 10 godina, posebno kod imunokompromitovanih pacijenata. Čak 10% infekcija kod hospitalizovanih pacijenata izazvano je gljivama. S obzirom da je pojava rezistencije na komercijalne fungicide učestala, javlja se potreba za novim alternativnim antifungalnim agensima. Prirodni produkti dobijaju sve veći značaj u tretmanu infektivnih oboljenja zbog svog netoksičnog karaktera visoke biodegradibilnosti i efikasnosti. Etarska ulja izolovana iz biljaka pokazuju veoma dobru antimikrobnu aktivnost. Eksperimentalna dermatomikoza kod Wistar pacova u ovom radu izazvana je dermatomicetom Trichophyton mentagrophytes. Prvi simptomi pojavili su se nakon 5 dana od inokulacije. Tretman etarskim uljem vrste Lavandula angustifolia, 1% rastvorom počeo je odmah nakon pojave prvih simptoma. Poboljšanje simptoma primećeno je nakon dva dana tretmana, a posle 13 dana od početka tretmana životinje su u potpunosti izlečene, na SDA podlogama nije bilo zabeleženo prisustvo patogena. Bifonazol je doveo do izlečenja nakon 15 dana tretmana. Etarsko ulje Lavandula angustifolia pokazalo je izuzetno jak antifungalni potencijal u tretmanu eksperimentalno indukovane dermatomikoze kod pacova, bolje od komercijalnog mikotika, bifonazola, koji je korišćen kao pozitivna kontrola.
T2  - Zbornik Matice srpske za prirodne nauke
T1  - Eksperimentalno indukovana dermatomikoza kod pacova i tretman etarskim uljem Lavadula angustifolia
T1  - Experimentally induced dermatomycoses at rats and treatment with Lavandula angustifolia essential oil
IS  - 113
VL  - null
SP  - 249
EP  - 254
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_540
ER  - 

@article{
author = "Glamočlija, Jasmina and Marin, Petar D. and Brkić, Dejan D. and Soković, Marina and Vukojević, Jelena B. and Jovanović, Dragutin and Bulajić, Nina and Kataranovski, Dragan S.",
year = "2007, 2007",
abstract = "The in vivo evaluation of antifungal activity of the Lavandula angustifolia essential oil was made on two-month old male Wistar rats. We examined the therapeutic potency against experimentally induced dermatomycoses in rats using the most frequent dermatomycetes, Trichophyton mentagrophytes. The therapeutic efficacy of 1% solution of essential oil as well as commercial preparation-bifonazole, was evaluated. During the 13-day observation period the oil-treated animals were cured completely., Infekcije ljudi uzrokovane gljivama su u znatnom porastu u poslednjih 10 godina, posebno kod imunokompromitovanih pacijenata. Čak 10% infekcija kod hospitalizovanih pacijenata izazvano je gljivama. S obzirom da je pojava rezistencije na komercijalne fungicide učestala, javlja se potreba za novim alternativnim antifungalnim agensima. Prirodni produkti dobijaju sve veći značaj u tretmanu infektivnih oboljenja zbog svog netoksičnog karaktera visoke biodegradibilnosti i efikasnosti. Etarska ulja izolovana iz biljaka pokazuju veoma dobru antimikrobnu aktivnost. Eksperimentalna dermatomikoza kod Wistar pacova u ovom radu izazvana je dermatomicetom Trichophyton mentagrophytes. Prvi simptomi pojavili su se nakon 5 dana od inokulacije. Tretman etarskim uljem vrste Lavandula angustifolia, 1% rastvorom počeo je odmah nakon pojave prvih simptoma. Poboljšanje simptoma primećeno je nakon dva dana tretmana, a posle 13 dana od početka tretmana životinje su u potpunosti izlečene, na SDA podlogama nije bilo zabeleženo prisustvo patogena. Bifonazol je doveo do izlečenja nakon 15 dana tretmana. Etarsko ulje Lavandula angustifolia pokazalo je izuzetno jak antifungalni potencijal u tretmanu eksperimentalno indukovane dermatomikoze kod pacova, bolje od komercijalnog mikotika, bifonazola, koji je korišćen kao pozitivna kontrola.",
journal = "Zbornik Matice srpske za prirodne nauke",
title = "Eksperimentalno indukovana dermatomikoza kod pacova i tretman etarskim uljem Lavadula angustifolia, Experimentally induced dermatomycoses at rats and treatment with Lavandula angustifolia essential oil",
number = "113",
volume = "null",
pages = "249-254",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_540"
}

Glamočlija, J., Marin, P. D., Brkić, D. D., Soković, M., Vukojević, J. B., Jovanović, D., Bulajić, N.,& Kataranovski, D. S.. (2007). Eksperimentalno indukovana dermatomikoza kod pacova i tretman etarskim uljem Lavadula angustifolia. in Zbornik Matice srpske za prirodne nauke, null(113), 249-254.
https://hdl.handle.net/21.15107/rcub_ibiss_540

Glamočlija J, Marin PD, Brkić DD, Soković M, Vukojević JB, Jovanović D, Bulajić N, Kataranovski DS. Eksperimentalno indukovana dermatomikoza kod pacova i tretman etarskim uljem Lavadula angustifolia. in Zbornik Matice srpske za prirodne nauke. 2007;null(113):249-254.
https://hdl.handle.net/21.15107/rcub_ibiss_540 .

Glamočlija, Jasmina, Marin, Petar D., Brkić, Dejan D., Soković, Marina, Vukojević, Jelena B., Jovanović, Dragutin, Bulajić, Nina, Kataranovski, Dragan S., "Eksperimentalno indukovana dermatomikoza kod pacova i tretman etarskim uljem Lavadula angustifolia" in Zbornik Matice srpske za prirodne nauke, null, no. 113 (2007):249-254,
https://hdl.handle.net/21.15107/rcub_ibiss_540 .

TY  - JOUR
AU  - Marin, Petar D
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
AU  - Brkić, Dejan D
AU  - Vukojević, Jelena B.
AU  - Jovanović, Dragutin
AU  - Bulajić, Nina
AU  - Kataranovski, Dragan S.
PY  - 2006
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1632
AB  - The in vivo evaluation of toxicological and antifungal activity of the Mentha x piperita L. essential oils and menthol was made on 2-month-old male Wistar rats. We examined the therapeutic potency against experimentally induced dermatomycoses in rats using the most frequent dermatomycetes, Trichophyton mentagrophytes, T. rubrum, and T. tonsurans. The therapeutic efficacy of 1% solution of essential oil and menthol, as well as commercial preparation bifonazole, was evaluated. During the 36-day observation period, the oil-treated animals were cured completely.
T2  - Pharmaceutical Biology
T1  - Antifungal activity of the essential oil of Mentha x piperita
IS  - 7
VL  - 44
EP  - 515
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1632
ER  - 

@article{
author = "Marin, Petar D and Glamočlija, Jasmina and Soković, Marina and Brkić, Dejan D and Vukojević, Jelena B. and Jovanović, Dragutin and Bulajić, Nina and Kataranovski, Dragan S.",
year = "2006",
abstract = "The in vivo evaluation of toxicological and antifungal activity of the Mentha x piperita L. essential oils and menthol was made on 2-month-old male Wistar rats. We examined the therapeutic potency against experimentally induced dermatomycoses in rats using the most frequent dermatomycetes, Trichophyton mentagrophytes, T. rubrum, and T. tonsurans. The therapeutic efficacy of 1% solution of essential oil and menthol, as well as commercial preparation bifonazole, was evaluated. During the 36-day observation period, the oil-treated animals were cured completely.",
journal = "Pharmaceutical Biology",
title = "Antifungal activity of the essential oil of Mentha x piperita",
number = "7",
volume = "44",
pages = "515",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1632"
}

Marin, P. D., Glamočlija, J., Soković, M., Brkić, D. D., Vukojević, J. B., Jovanović, D., Bulajić, N.,& Kataranovski, D. S.. (2006). Antifungal activity of the essential oil of Mentha x piperita. in Pharmaceutical Biology, 44(7).
https://hdl.handle.net/21.15107/rcub_ibiss_1632

Marin PD, Glamočlija J, Soković M, Brkić DD, Vukojević JB, Jovanović D, Bulajić N, Kataranovski DS. Antifungal activity of the essential oil of Mentha x piperita. in Pharmaceutical Biology. 2006;44(7):null-515.
https://hdl.handle.net/21.15107/rcub_ibiss_1632 .

Marin, Petar D, Glamočlija, Jasmina, Soković, Marina, Brkić, Dejan D, Vukojević, Jelena B., Jovanović, Dragutin, Bulajić, Nina, Kataranovski, Dragan S., "Antifungal activity of the essential oil of Mentha x piperita" in Pharmaceutical Biology, 44, no. 7 (2006),
https://hdl.handle.net/21.15107/rcub_ibiss_1632 .