Arenas, Conxita

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  • Arenas, Conxita (5)
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Author's Bibliography

Rate of change for the thermal adapted inversions in Drosophila subobscura.

Živanović, Goran; Arenas, Conxita; Mestres, Francesc

(2019)

TY  - JOUR
AU  - Živanović, Goran
AU  - Arenas, Conxita
AU  - Mestres, Francesc
PY  - 2019
UR  - http://link.springer.com/10.1007/s10709-019-00078-y
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3511
AB  - The changes of chromosomal inversion polymorphism composition of Drosophila subobscura in samples from Apatin (Serbia) were studied in a 24-years interval (1994-2018). The variation was significant for all autosomes and directional, increasing the inversions considered as 'warm', whereas those reported as 'cold' decreased. Furthermore, the Chromosomal Thermal Index (CTI), which allows studying the thermal adaptation of the whole karyotype increased significantly in that period of time. These results were in agreement with the indicators of global warming in Apatin: a trend to increase of the mean, maximum and minimum (this latter even significant) temperatures, and an erratic pattern of rainfall (also usual in global warming). The deviations from the Wright-Fisher model of genetic drift were used to consider the possible effect of migration or selection as evolutionary factors responsible for the change in inversion frequencies. To quantify approximately the rate of change in the frequencies, for each kind of inversions ('cold', 'warm' and 'non-thermal adapted'), the difference in frequency between the Apatin samples obtained in 1994 and 2018 was computed and then it was divided by the number of years elapsed. This rate was always higher (from twice as many as thirty times more depending on the autosome) for thermal adapted inversions ('cold' or 'warm') than the 'non-thermal' adapted. From this study, it could be concluded that the chromosomal inversions of D. subobscura could change (in composition and frequencies) in a predictable direction and a rather 'rapid' rhythm to adapt to the global warming scenario.
T2  - Genetica
T1  - Rate of change for the thermal adapted inversions in Drosophila subobscura.
DO  - 10.1007/s10709-019-00078-y
ER  - 
@article{
author = "Živanović, Goran and Arenas, Conxita and Mestres, Francesc",
year = "2019",
abstract = "The changes of chromosomal inversion polymorphism composition of Drosophila subobscura in samples from Apatin (Serbia) were studied in a 24-years interval (1994-2018). The variation was significant for all autosomes and directional, increasing the inversions considered as 'warm', whereas those reported as 'cold' decreased. Furthermore, the Chromosomal Thermal Index (CTI), which allows studying the thermal adaptation of the whole karyotype increased significantly in that period of time. These results were in agreement with the indicators of global warming in Apatin: a trend to increase of the mean, maximum and minimum (this latter even significant) temperatures, and an erratic pattern of rainfall (also usual in global warming). The deviations from the Wright-Fisher model of genetic drift were used to consider the possible effect of migration or selection as evolutionary factors responsible for the change in inversion frequencies. To quantify approximately the rate of change in the frequencies, for each kind of inversions ('cold', 'warm' and 'non-thermal adapted'), the difference in frequency between the Apatin samples obtained in 1994 and 2018 was computed and then it was divided by the number of years elapsed. This rate was always higher (from twice as many as thirty times more depending on the autosome) for thermal adapted inversions ('cold' or 'warm') than the 'non-thermal' adapted. From this study, it could be concluded that the chromosomal inversions of D. subobscura could change (in composition and frequencies) in a predictable direction and a rather 'rapid' rhythm to adapt to the global warming scenario.",
journal = "Genetica",
title = "Rate of change for the thermal adapted inversions in Drosophila subobscura.",
doi = "10.1007/s10709-019-00078-y"
}
Živanović, G., Arenas, C.,& Mestres, F.. (2019). Rate of change for the thermal adapted inversions in Drosophila subobscura.. in Genetica.
https://doi.org/10.1007/s10709-019-00078-y
Živanović G, Arenas C, Mestres F. Rate of change for the thermal adapted inversions in Drosophila subobscura.. in Genetica. 2019;.
doi:10.1007/s10709-019-00078-y .
Živanović, Goran, Arenas, Conxita, Mestres, Francesc, "Rate of change for the thermal adapted inversions in Drosophila subobscura." in Genetica (2019),
https://doi.org/10.1007/s10709-019-00078-y . .
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Chromosomal Thermal Index: a comprehensive way to integrate the thermal adaptation of Drosophila subobscura whole karyotype.

Arenas, Conxita; Živanović, Goran; Mestres, Francesc

(Canadian Science Publishing, 2018)

TY  - JOUR
AU  - Arenas, Conxita
AU  - Živanović, Goran
AU  - Mestres, Francesc
PY  - 2018
UR  - http://www.nrcresearchpress.com/doi/10.1139/gen-2017-0124
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3001
AB  - Drosophila has demonstrated to be an excellent model to study the adaptation of organisms to global warming, with inversion chromosomal polymorphism having a key role in this adaptation. Here, we introduce a new index (Chromosomal Thermal Index or CTI) to quantify the thermal adaptation of a population according to its composition of "warm" and "cold" adapted inversions. This index is intuitive, has good statistical properties, and can be used to hypothesis on the effect of global warming on natural populations. We show the usefulness of CTI using data from European populations of D. subobscura, sampled in different years. Out of 15 comparisons over time, nine showed significant increase of CTI, in accordance with global warming expectations. Although large regions of the genome outside inversions contain thermal adaptation genes, our results show that the total amount of warm or cold inversions in populations seems to be directly involved in thermal adaptation, whereas the interactions between the inversions content of homologous and non-homologous chromosomes are not relevant.
PB  - Canadian Science Publishing
T2  - Genome
T1  - Chromosomal Thermal Index: a comprehensive way to integrate the thermal adaptation of Drosophila subobscura whole karyotype.
IS  - 2
VL  - 61
DO  - 10.1139/gen-2017-0124
SP  - 73
EP  - 78
ER  - 
@article{
author = "Arenas, Conxita and Živanović, Goran and Mestres, Francesc",
year = "2018",
abstract = "Drosophila has demonstrated to be an excellent model to study the adaptation of organisms to global warming, with inversion chromosomal polymorphism having a key role in this adaptation. Here, we introduce a new index (Chromosomal Thermal Index or CTI) to quantify the thermal adaptation of a population according to its composition of "warm" and "cold" adapted inversions. This index is intuitive, has good statistical properties, and can be used to hypothesis on the effect of global warming on natural populations. We show the usefulness of CTI using data from European populations of D. subobscura, sampled in different years. Out of 15 comparisons over time, nine showed significant increase of CTI, in accordance with global warming expectations. Although large regions of the genome outside inversions contain thermal adaptation genes, our results show that the total amount of warm or cold inversions in populations seems to be directly involved in thermal adaptation, whereas the interactions between the inversions content of homologous and non-homologous chromosomes are not relevant.",
publisher = "Canadian Science Publishing",
journal = "Genome",
title = "Chromosomal Thermal Index: a comprehensive way to integrate the thermal adaptation of Drosophila subobscura whole karyotype.",
number = "2",
volume = "61",
doi = "10.1139/gen-2017-0124",
pages = "73-78"
}
Arenas, C., Živanović, G.,& Mestres, F.. (2018). Chromosomal Thermal Index: a comprehensive way to integrate the thermal adaptation of Drosophila subobscura whole karyotype.. in Genome
Canadian Science Publishing., 61(2), 73-78.
https://doi.org/10.1139/gen-2017-0124
Arenas C, Živanović G, Mestres F. Chromosomal Thermal Index: a comprehensive way to integrate the thermal adaptation of Drosophila subobscura whole karyotype.. in Genome. 2018;61(2):73-78.
doi:10.1139/gen-2017-0124 .
Arenas, Conxita, Živanović, Goran, Mestres, Francesc, "Chromosomal Thermal Index: a comprehensive way to integrate the thermal adaptation of Drosophila subobscura whole karyotype." in Genome, 61, no. 2 (2018):73-78,
https://doi.org/10.1139/gen-2017-0124 . .
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Medium-term changes in Drosophila subobscura chromosomal inversion polymorphism: a possible relation with global warming?

Živanović, Goran; Arenas, Conxita; Mestres, Francesc

(2015)

TY  - JOUR
AU  - Živanović, Goran
AU  - Arenas, Conxita
AU  - Mestres, Francesc
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1944
T2  - Journal of Genetics
T1  - Medium-term changes in Drosophila subobscura chromosomal inversion
 polymorphism: a possible relation with global warming?
IS  - 2
VL  - 94
SP  - 343
EP  - 346
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1944
ER  - 
@article{
author = "Živanović, Goran and Arenas, Conxita and Mestres, Francesc",
year = "2015",
journal = "Journal of Genetics",
title = "Medium-term changes in Drosophila subobscura chromosomal inversion
 polymorphism: a possible relation with global warming?",
number = "2",
volume = "94",
pages = "343-346",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1944"
}
Živanović, G., Arenas, C.,& Mestres, F.. (2015). Medium-term changes in Drosophila subobscura chromosomal inversion
 polymorphism: a possible relation with global warming?. in Journal of Genetics, 94(2), 343-346.
https://hdl.handle.net/21.15107/rcub_ibiss_1944
Živanović G, Arenas C, Mestres F. Medium-term changes in Drosophila subobscura chromosomal inversion
 polymorphism: a possible relation with global warming?. in Journal of Genetics. 2015;94(2):343-346.
https://hdl.handle.net/21.15107/rcub_ibiss_1944 .
Živanović, Goran, Arenas, Conxita, Mestres, Francesc, "Medium-term changes in Drosophila subobscura chromosomal inversion
 polymorphism: a possible relation with global warming?" in Journal of Genetics, 94, no. 2 (2015):343-346,
https://hdl.handle.net/21.15107/rcub_ibiss_1944 .
7

Inbreeding and thermal adaptation in Drosophila subobscura

Živanović, Goran; Arenas, Conxita; Mestres, Francesc

(2014)

TY  - JOUR
AU  - Živanović, Goran
AU  - Arenas, Conxita
AU  - Mestres, Francesc
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2161
AB  - Using a well-adapted Drosophila subobscura population (Avala, Serbia), a
   drastic experiment of inbreeding was carried out to assess whether the
   expected level of homozygosity could be reached or if other evolutionary
   forces affected the process. In general, no significant changes of
   inversion (or arrangement) frequencies were detected after 12
   brother-sister mating generations. Furthermore, no significant
   differences were obtained between observed and expected (under the
   inbreeding model) karyotypic frequencies. Thus, these results seemed to
   indicate that the main evolutionary factor in the experiment was
   inbreeding. However, in the G(12) generation, complete chromosomal
   fixation was reached only in two out of the eight final inbred lines. In
   these lines, the chromosomal compositions were difficult to interpret,
   but they could be likely a consequence of adaptation to particular
   laboratory conditions (constant 18 degrees C, food, light period, etc.).
   Finally, in a second experiment, the inbred lines presented higher
   fertility at 18 degrees C than at 13 degrees C. Also, there was a
   significant line effect on fertility: inbred line number 6 (A(1), J(1),
   U(1) under bar+(2) under bar; U(1) under bar+(2) under bar+(6) under
   bar, E-8, and O (3) under bar (+(4) under bar+(7) under bar)) presented
   the highest values, which maybe the result of an adaptation to
   laboratory conditions. Thus, the results obtained in our experiments
   reflect the adaptive potential of D. subobscura inversions.
T2  - Genome
T1  - Inbreeding and thermal adaptation in Drosophila subobscura
IS  - 9
VL  - 57
DO  - 10.1139/gen-2014-0149
SP  - 481
EP  - 488
ER  - 
@article{
author = "Živanović, Goran and Arenas, Conxita and Mestres, Francesc",
year = "2014",
abstract = "Using a well-adapted Drosophila subobscura population (Avala, Serbia), a
   drastic experiment of inbreeding was carried out to assess whether the
   expected level of homozygosity could be reached or if other evolutionary
   forces affected the process. In general, no significant changes of
   inversion (or arrangement) frequencies were detected after 12
   brother-sister mating generations. Furthermore, no significant
   differences were obtained between observed and expected (under the
   inbreeding model) karyotypic frequencies. Thus, these results seemed to
   indicate that the main evolutionary factor in the experiment was
   inbreeding. However, in the G(12) generation, complete chromosomal
   fixation was reached only in two out of the eight final inbred lines. In
   these lines, the chromosomal compositions were difficult to interpret,
   but they could be likely a consequence of adaptation to particular
   laboratory conditions (constant 18 degrees C, food, light period, etc.).
   Finally, in a second experiment, the inbred lines presented higher
   fertility at 18 degrees C than at 13 degrees C. Also, there was a
   significant line effect on fertility: inbred line number 6 (A(1), J(1),
   U(1) under bar+(2) under bar; U(1) under bar+(2) under bar+(6) under
   bar, E-8, and O (3) under bar (+(4) under bar+(7) under bar)) presented
   the highest values, which maybe the result of an adaptation to
   laboratory conditions. Thus, the results obtained in our experiments
   reflect the adaptive potential of D. subobscura inversions.",
journal = "Genome",
title = "Inbreeding and thermal adaptation in Drosophila subobscura",
number = "9",
volume = "57",
doi = "10.1139/gen-2014-0149",
pages = "481-488"
}
Živanović, G., Arenas, C.,& Mestres, F.. (2014). Inbreeding and thermal adaptation in Drosophila subobscura. in Genome, 57(9), 481-488.
https://doi.org/10.1139/gen-2014-0149
Živanović G, Arenas C, Mestres F. Inbreeding and thermal adaptation in Drosophila subobscura. in Genome. 2014;57(9):481-488.
doi:10.1139/gen-2014-0149 .
Živanović, Goran, Arenas, Conxita, Mestres, Francesc, "Inbreeding and thermal adaptation in Drosophila subobscura" in Genome, 57, no. 9 (2014):481-488,
https://doi.org/10.1139/gen-2014-0149 . .
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Short- and Long-Term Changes in Chromosomal Inversion Polymorphism and Global Warming: Drosophila Subobscura From the Balkans

Živanović, Goran; Arenas, Conxita; Mestres, Francesc

(2012)

TY  - JOUR
AU  - Živanović, Goran
AU  - Arenas, Conxita
AU  - Mestres, Francesc
PY  - 2012
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1214
AB  - The chromosomal inversion polymorphism of Drosophila subobscura is adaptive to environmental changes. The population of Petnica, Serbia, was chosen to analyze short- and long-term changes in this polymorphism. Short-term changes were studied in the samples collected in May, June, and August of 1995. The inversion polymorphism varied over these months, although various interpretations are possible. To analyze long-term changes, samples obtained in May 1995 and May 2010 were compared. The frequency of the "cold" adapted inversions (A(st), J(st), U-st, E-st, and O-st) decreased and that of the "warm" adapted inversions (A(2), J(1), U1+2, and O3+4) increased, from 1995 to 2010. These changes are consistent with the general increase in temperature recorded in Petnica for the same period. Finally, the possible response of chromosomal polymorphism to global warming was analyzed at the regional level (Balkan peninsula). This polymorphism depends on the ecological conditions of the populations, and the changes observed appear to be consistent with global warming expectations. Natural selection seems to be the main mechanism responsible for the evolution of this chromosomal polymorphism.
T2  - Israel Journal of Ecology & Evolution
T1  - Short- and Long-Term Changes in Chromosomal Inversion Polymorphism and Global Warming: Drosophila Subobscura From the Balkans
IS  - 4
VL  - 58
EP  - 311
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1214
ER  - 
@article{
author = "Živanović, Goran and Arenas, Conxita and Mestres, Francesc",
year = "2012",
abstract = "The chromosomal inversion polymorphism of Drosophila subobscura is adaptive to environmental changes. The population of Petnica, Serbia, was chosen to analyze short- and long-term changes in this polymorphism. Short-term changes were studied in the samples collected in May, June, and August of 1995. The inversion polymorphism varied over these months, although various interpretations are possible. To analyze long-term changes, samples obtained in May 1995 and May 2010 were compared. The frequency of the "cold" adapted inversions (A(st), J(st), U-st, E-st, and O-st) decreased and that of the "warm" adapted inversions (A(2), J(1), U1+2, and O3+4) increased, from 1995 to 2010. These changes are consistent with the general increase in temperature recorded in Petnica for the same period. Finally, the possible response of chromosomal polymorphism to global warming was analyzed at the regional level (Balkan peninsula). This polymorphism depends on the ecological conditions of the populations, and the changes observed appear to be consistent with global warming expectations. Natural selection seems to be the main mechanism responsible for the evolution of this chromosomal polymorphism.",
journal = "Israel Journal of Ecology & Evolution",
title = "Short- and Long-Term Changes in Chromosomal Inversion Polymorphism and Global Warming: Drosophila Subobscura From the Balkans",
number = "4",
volume = "58",
pages = "311",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1214"
}
Živanović, G., Arenas, C.,& Mestres, F.. (2012). Short- and Long-Term Changes in Chromosomal Inversion Polymorphism and Global Warming: Drosophila Subobscura From the Balkans. in Israel Journal of Ecology & Evolution, 58(4).
https://hdl.handle.net/21.15107/rcub_ibiss_1214
Živanović G, Arenas C, Mestres F. Short- and Long-Term Changes in Chromosomal Inversion Polymorphism and Global Warming: Drosophila Subobscura From the Balkans. in Israel Journal of Ecology & Evolution. 2012;58(4):null-311.
https://hdl.handle.net/21.15107/rcub_ibiss_1214 .
Živanović, Goran, Arenas, Conxita, Mestres, Francesc, "Short- and Long-Term Changes in Chromosomal Inversion Polymorphism and Global Warming: Drosophila Subobscura From the Balkans" in Israel Journal of Ecology & Evolution, 58, no. 4 (2012),
https://hdl.handle.net/21.15107/rcub_ibiss_1214 .